BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 22242187)

  • 1. Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors.
    Tagne JB; Gupta S; Gower AC; Shen SS; Varma S; Lakshminarayanan M; Cao Y; Spira A; Volkert TL; Ramirez MI
    PLoS One; 2012; 7(1):e29907. PubMed ID: 22242187
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcription factor and microRNA interactions in lung cells: an inhibitory link between NK2 homeobox 1, miR-200c and the developmental and oncogenic factors Nfib and Myb.
    Tagne JB; Mohtar OR; Campbell JD; Lakshminarayanan M; Huang J; Hinds AC; Lu J; Ramirez MI
    Respir Res; 2015 Feb; 16(1):22. PubMed ID: 25763778
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation.
    Varma S; Cao Y; Tagne JB; Lakshminarayanan M; Li J; Friedman TB; Morell RJ; Warburton D; Kotton DN; Ramirez MI
    J Biol Chem; 2012 Oct; 287(44):37282-95. PubMed ID: 22955271
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.
    Maeda Y; Tsuchiya T; Hao H; Tompkins DH; Xu Y; Mucenski ML; Du L; Keiser AR; Fukazawa T; Naomoto Y; Nagayasu T; Whitsett JA
    J Clin Invest; 2012 Dec; 122(12):4388-400. PubMed ID: 23143308
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thyroid transcription factor-1-regulated microRNA-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells.
    Griesing S; Kajino T; Tai MC; Liu Z; Nakatochi M; Shimada Y; Suzuki M; Takahashi T
    Cancer Sci; 2017 Jul; 108(7):1394-1404. PubMed ID: 28474808
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target.
    Watanabe H; Francis JM; Woo MS; Etemad B; Lin W; Fries DF; Peng S; Snyder EL; Tata PR; Izzo F; Schinzel AC; Cho J; Hammerman PS; Verhaak RG; Hahn WC; Rajagopal J; Jacks T; Meyerson M
    Genes Dev; 2013 Jan; 27(2):197-210. PubMed ID: 23322301
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppression of lung adenocarcinoma progression by Nkx2-1.
    Winslow MM; Dayton TL; Verhaak RG; Kim-Kiselak C; Snyder EL; Feldser DM; Hubbard DD; DuPage MJ; Whittaker CA; Hoersch S; Yoon S; Crowley D; Bronson RT; Chiang DY; Meyerson M; Jacks T
    Nature; 2011 May; 473(7345):101-4. PubMed ID: 21471965
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
    Snyder EL; Watanabe H; Magendantz M; Hoersch S; Chen TA; Wang DG; Crowley D; Whittaker CA; Meyerson M; Kimura S; Jacks T
    Mol Cell; 2013 Apr; 50(2):185-99. PubMed ID: 23523371
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas.
    Tsai LH; Chen PM; Cheng YW; Chen CY; Sheu GT; Wu TC; Lee H
    Oncogene; 2014 Jul; 33(29):3851-60. PubMed ID: 23995788
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparative analysis of TTF-1 binding DNA regions in small-cell lung cancer and non-small-cell lung cancer.
    Hokari S; Tamura Y; Kaneda A; Katsura A; Morikawa M; Murai F; Ehata S; Tsutsumi S; Ishikawa Y; Aburatani H; Kikuchi T; Miyazono K; Koinuma D
    Mol Oncol; 2020 Feb; 14(2):277-293. PubMed ID: 31782890
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Homeobox Transcription Factor NKX2-1 Promotes
    Harada M; Sakai S; Ohhata T; Kitagawa K; Mikamo M; Nishimoto K; Uchida C; Niida H; Kotake Y; Sugimura H; Suda T; Kitagawa M
    Mol Cancer Res; 2017 Oct; 15(10):1388-1397. PubMed ID: 28634225
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Integrative Genomics Implicates EGFR as a Downstream Mediator in NKX2-1 Amplified Non-Small Cell Lung Cancer.
    Clarke N; Biscocho J; Kwei KA; Davidson JM; Sridhar S; Gong X; Pollack JR
    PLoS One; 2015; 10(11):e0142061. PubMed ID: 26556242
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transforming growth factor-beta inhibits pulmonary surfactant protein B gene transcription through SMAD3 interactions with NKX2.1 and HNF-3 transcription factors.
    Li C; Zhu NL; Tan RC; Ballard PL; Derynck R; Minoo P
    J Biol Chem; 2002 Oct; 277(41):38399-408. PubMed ID: 12161428
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells.
    D'Almeida O; Mothar O; Bondzie EA; Lieumo Y; Tagne L; Gupta S; Volkert T; Levine S; Tagne JB
    BMC Cancer; 2019 Feb; 19(1):136. PubMed ID: 30744585
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic transactivation of the differentiation-dependent lung gene Clara cell secretory protein (secretoglobin 1a1) by the basic region leucine zipper factor CCAAT/enhancer-binding protein alpha and the homeodomain factor Nkx2.1/thyroid transcription factor-1.
    Cassel TN; Berg T; Suske G; Nord M
    J Biol Chem; 2002 Oct; 277(40):36970-7. PubMed ID: 12161423
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CRISPRi-mediated functional analysis of NKX2-1-binding sites in the lung.
    Stuart WD; Fink-Baldauf IM; Tomoshige K; Guo M; Maeda Y
    Commun Biol; 2021 May; 4(1):568. PubMed ID: 33980985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.
    Minoo P; Hu L; Xing Y; Zhu NL; Chen H; Li M; Borok Z; Li C
    Mol Cell Biol; 2007 Mar; 27(6):2155-65. PubMed ID: 17220277
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NKX2.1 regulates transcription of the gene for human bone morphogenetic protein-4 in lung epithelial cells.
    Zhu NL; Li C; Xiao J; Minoo P
    Gene; 2004 Feb; 327(1):25-36. PubMed ID: 14960358
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The complexity of thyroid transcription factor 1 with both pro- and anti-oncogenic activities.
    Mu D
    J Biol Chem; 2013 Aug; 288(35):24992-25000. PubMed ID: 23818522
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1).
    Runkle EA; Rice SJ; Qi J; Masser D; Antonetti DA; Winslow MM; Mu D
    J Biol Chem; 2012 Aug; 287(34):28790-801. PubMed ID: 22761434
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.