BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 22242859)

  • 1. Development of FXR, PXR and CAR agonists and antagonists for treatment of liver disorders.
    Fiorucci S; Zampella A; Distrutti E
    Curr Top Med Chem; 2012; 12(6):605-24. PubMed ID: 22242859
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
    Wagner M; Halilbasic E; Marschall HU; Zollner G; Fickert P; Langner C; Zatloukal K; Denk H; Trauner M
    Hepatology; 2005 Aug; 42(2):420-30. PubMed ID: 15986414
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Marine sponge steroids as nuclear receptor ligands.
    Fiorucci S; Distrutti E; Bifulco G; D'Auria MV; Zampella A
    Trends Pharmacol Sci; 2012 Nov; 33(11):591-601. PubMed ID: 23000093
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.
    Guo GL; Lambert G; Negishi M; Ward JM; Brewer HB; Kliewer SA; Gonzalez FJ; Sinal CJ
    J Biol Chem; 2003 Nov; 278(46):45062-71. PubMed ID: 12923173
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Farnesoid X receptor: from medicinal chemistry to clinical applications.
    Fiorucci S; Mencarelli A; Distrutti E; Zampella A
    Future Med Chem; 2012 May; 4(7):877-91. PubMed ID: 22571613
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The decrease in farnesoid X receptor, pregnane X receptor and constitutive androstane receptor in the liver after intestinal ischemia-reperfusion.
    Ogura J; Terada Y; Tsujimoto T; Koizumi T; Kuwayama K; Maruyama H; Fujikawa A; Takaya A; Kobayashi M; Itagaki S; Takahashi N; Hirano T; Yamaguchi H; Iseki K
    J Pharm Pharm Sci; 2012; 15(5):616-31. PubMed ID: 23331901
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Farnesoid X receptor agonists in biliary tract disease.
    Fiorucci S; Baldelli F
    Curr Opin Gastroenterol; 2009 May; 25(3):252-9. PubMed ID: 19300246
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FXR and PXR: potential therapeutic targets in cholestasis.
    Jonker JW; Liddle C; Downes M
    J Steroid Biochem Mol Biol; 2012 Jul; 130(3-5):147-58. PubMed ID: 21801835
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pregnane X receptor is a target of farnesoid X receptor.
    Jung D; Mangelsdorf DJ; Meyer UA
    J Biol Chem; 2006 Jul; 281(28):19081-91. PubMed ID: 16682417
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR).
    Chang TK; Waxman DJ
    Drug Metab Rev; 2006; 38(1-2):51-73. PubMed ID: 16684648
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors.
    Ricketts ML; Boekschoten MV; Kreeft AJ; Hooiveld GJ; Moen CJ; Müller M; Frants RR; Kasanmoentalib S; Post SM; Princen HM; Porter JG; Katan MB; Hofker MH; Moore DD
    Mol Endocrinol; 2007 Jul; 21(7):1603-16. PubMed ID: 17456796
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists.
    De Marino S; Festa C; Sepe V; Zampella A
    Handb Exp Pharmacol; 2019; 256():137-165. PubMed ID: 31201554
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier.
    Whyte-Allman SK; Hoque MT; Jenabian MA; Routy JP; Bendayan R
    J Pharmacol Exp Ther; 2017 Dec; 363(3):324-335. PubMed ID: 28970358
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders.
    Fiorucci S; Sepe V; Biagioli M; Fiorillo B; Rapacciuolo P; Distrutti E; Zampella A
    Biochem Pharmacol; 2023 Oct; 216():115776. PubMed ID: 37659739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting farnesoid X receptor for liver and metabolic disorders.
    Fiorucci S; Rizzo G; Donini A; Distrutti E; Santucci L
    Trends Mol Med; 2007 Jul; 13(7):298-309. PubMed ID: 17588816
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro.
    Gao X; Fu T; Wang C; Ning C; Liu K; Liu Z; Sun H; Ma X; Huo X; Yang X; Zou M; Meng Q
    Toxicol Appl Pharmacol; 2018 Jun; 348():105-116. PubMed ID: 29660435
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis.
    Renga B; Mencarelli A; D'Amore C; Cipriani S; D'Auria MV; Sepe V; Chini MG; Monti MC; Bifulco G; Zampella A; Fiorucci S
    PLoS One; 2012; 7(1):e30443. PubMed ID: 22291955
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species.
    Krasowski MD; Ai N; Hagey LR; Kollitz EM; Kullman SW; Reschly EJ; Ekins S
    BMC Biochem; 2011 Feb; 12():5. PubMed ID: 21291553
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bile acid promotes liver regeneration via farnesoid X receptor signaling pathways in rats.
    Ding L; Yang Y; Qu Y; Yang T; Wang K; Liu W; Xia W
    Mol Med Rep; 2015 Jun; 11(6):4431-7. PubMed ID: 25634785
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei.
    Sepe V; Ummarino R; D'Auria MV; Chini MG; Bifulco G; Renga B; D'Amore C; Debitus C; Fiorucci S; Zampella A
    J Med Chem; 2012 Jan; 55(1):84-93. PubMed ID: 22126372
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.