637 related articles for article (PubMed ID: 22243403)
1. Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.
Kumar VP; Thomas LM; Bobyk KD; Andi B; Cook PF; West AH
Biochemistry; 2012 Jan; 51(4):857-66. PubMed ID: 22243403
[TBL] [Abstract][Full Text] [Related]
2. A proposed proton shuttle mechanism for saccharopine dehydrogenase from Saccharomyces cerevisiae.
Xu H; Alguindigue SS; West AH; Cook PF
Biochemistry; 2007 Jan; 46(3):871-82. PubMed ID: 17223709
[TBL] [Abstract][Full Text] [Related]
3. The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.
Bobyk KD; Kim SG; Kumar VP; Kim SK; West AH; Cook PF
Arch Biochem Biophys; 2011 Sep; 513(2):71-80. PubMed ID: 21798231
[TBL] [Abstract][Full Text] [Related]
4. Chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae.
Vashishtha AK; West AH; Cook PF
Biochemistry; 2009 Jun; 48(25):5899-907. PubMed ID: 19449898
[TBL] [Abstract][Full Text] [Related]
5. Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.
Kumar VP; West AH; Cook PF
Arch Biochem Biophys; 2012 Jun; 522(1):57-61. PubMed ID: 22521736
[TBL] [Abstract][Full Text] [Related]
6. Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.
Xu H; West AH; Cook PF
Biochemistry; 2006 Oct; 45(39):12156-66. PubMed ID: 17002315
[TBL] [Abstract][Full Text] [Related]
7. Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis.
Vashishtha AK; West AH; Cook PF
Arch Biochem Biophys; 2015 Oct; 584():98-106. PubMed ID: 26342457
[TBL] [Abstract][Full Text] [Related]
8. Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.
Ekanayake DK; Andi B; Bobyk KD; West AH; Cook PF
J Biol Chem; 2010 Jul; 285(27):20756-68. PubMed ID: 20427272
[TBL] [Abstract][Full Text] [Related]
9. Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
Lin Y; West AH; Cook PF
Biochemistry; 2009 Aug; 48(30):7305-12. PubMed ID: 19530703
[TBL] [Abstract][Full Text] [Related]
10. Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction.
Ekanayake DK; West AH; Cook PF
Arch Biochem Biophys; 2011 Oct; 514(1-2):8-15. PubMed ID: 21819960
[TBL] [Abstract][Full Text] [Related]
11. Evidence for an induced conformational change in the catalytic mechanism of homoisocitrate dehydrogenase for Saccharomyces cerevisiae: Characterization of the D271N mutant enzyme.
Hsu C; West AH; Cook PF
Arch Biochem Biophys; 2015 Oct; 584():20-7. PubMed ID: 26325079
[TBL] [Abstract][Full Text] [Related]
12. Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
Lin Y; Volkman J; Nicholas KM; Yamamoto T; Eguchi T; Nimmo SL; West AH; Cook PF
Biochemistry; 2008 Apr; 47(13):4169-80. PubMed ID: 18321070
[TBL] [Abstract][Full Text] [Related]
13. A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme.
Karsten WE; Liu D; Rao GS; Harris BG; Cook PF
Biochemistry; 2005 Mar; 44(9):3626-35. PubMed ID: 15736972
[TBL] [Abstract][Full Text] [Related]
14. Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme.
Bohren KM; Grimshaw CE; Lai CJ; Harrison DH; Ringe D; Petsko GA; Gabbay KH
Biochemistry; 1994 Mar; 33(8):2021-32. PubMed ID: 8117659
[TBL] [Abstract][Full Text] [Related]
15. Structural studies of the final enzyme in the alpha-aminoadipate pathway-saccharopine dehydrogenase from Saccharomyces cerevisiae.
Burk DL; Hwang J; Kwok E; Marrone L; Goodfellow V; Dmitrienko GI; Berghuis AM
J Mol Biol; 2007 Oct; 373(3):745-54. PubMed ID: 17854830
[TBL] [Abstract][Full Text] [Related]
16. Roles of tyrosine 158 and lysine 165 in the catalytic mechanism of InhA, the enoyl-ACP reductase from Mycobacterium tuberculosis.
Parikh S; Moynihan DP; Xiao G; Tonge PJ
Biochemistry; 1999 Oct; 38(41):13623-34. PubMed ID: 10521269
[TBL] [Abstract][Full Text] [Related]
17. Crystal structure of saccharopine reductase from Magnaporthe grisea, an enzyme of the alpha-aminoadipate pathway of lysine biosynthesis.
Johansson E; Steffens JJ; Lindqvist Y; Schneider G
Structure; 2000 Oct; 8(10):1037-47. PubMed ID: 11080625
[TBL] [Abstract][Full Text] [Related]
18. Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae.
Xu H; West AH; Cook PF
Biochemistry; 2007 Jun; 46(25):7625-36. PubMed ID: 17542618
[TBL] [Abstract][Full Text] [Related]
19. Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae.
Qian J; West AH; Cook PF
Biochemistry; 2006 Oct; 45(39):12136-43. PubMed ID: 17002313
[TBL] [Abstract][Full Text] [Related]
20. Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae.
Andi B; Xu H; Cook PF; West AH
Biochemistry; 2007 Nov; 46(44):12512-21. PubMed ID: 17939687
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
