These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 22245152)

  • 1. Hypoxia-induced SM22α in A549 cells activates the IGF1R/PI3K/Akt pathway, conferring cellular resistance against chemo- and radiation therapy.
    Kim TR; Cho EW; Paik SG; Kim IG
    FEBS Lett; 2012 Feb; 586(4):303-9. PubMed ID: 22245152
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SM22alpha inhibits cell proliferation and protects against anticancer drugs and gamma-radiation in HepG2 cells: involvement of metallothioneins.
    Kim TR; Moon JH; Lee HM; Cho EW; Paik SG; Kim IG
    FEBS Lett; 2009 Oct; 583(20):3356-62. PubMed ID: 19796641
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia-inducible transgelin 2 selects epithelial-to-mesenchymal transition and γ-radiation-resistant subtypes by focal adhesion kinase-associated insulin-like growth factor 1 receptor activation in non-small-cell lung cancer cells.
    Kim IG; Lee JH; Kim SY; Hwang HM; Kim TR; Cho EW
    Cancer Sci; 2018 Nov; 109(11):3519-3531. PubMed ID: 30191639
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SM22α-induced activation of p16INK4a/retinoblastoma pathway promotes cellular senescence caused by a subclinical dose of γ-radiation and doxorubicin in HepG2 cells.
    Kim TR; Lee HM; Lee SY; Kim EJ; Kim KC; Paik SG; Cho EW; Kim IG
    Biochem Biophys Res Commun; 2010 Sep; 400(1):100-5. PubMed ID: 20705054
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway.
    Lee YC; Lin HH; Hsu CH; Wang CJ; Chiang TA; Chen JH
    Eur J Pharmacol; 2010 Apr; 632(1-3):23-32. PubMed ID: 20097193
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Upregulated expression of periostin by hypoxia in non-small-cell lung cancer cells promotes cell survival via the Akt/PKB pathway.
    Ouyang G; Liu M; Ruan K; Song G; Mao Y; Bao S
    Cancer Lett; 2009 Aug; 281(2):213-9. PubMed ID: 19328625
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene.
    Song X; Liu X; Chi W; Liu Y; Wei L; Wang X; Yu J
    Cancer Chemother Pharmacol; 2006 Dec; 58(6):776-84. PubMed ID: 16532342
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The PI3-K/AKT-pathway and radiation resistance mechanisms in non-small cell lung cancer.
    Schuurbiers OC; Kaanders JH; van der Heijden HF; Dekhuijzen RP; Oyen WJ; Bussink J
    J Thorac Oncol; 2009 Jun; 4(6):761-7. PubMed ID: 19404218
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The small-molecule CDK inhibitor, SNS-032, enhances cellular radiosensitivity in quiescent and hypoxic non-small cell lung cancer cells.
    Kodym E; Kodym R; Reis AE; Habib AA; Story MD; Saha D
    Lung Cancer; 2009 Oct; 66(1):37-47. PubMed ID: 19193471
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphatidylinositol 3-kinase/Akt pathway is involved in transforming growth factor-beta1-induced phenotypic modulation of 10T1/2 cells to smooth muscle cells.
    Lien SC; Usami S; Chien S; Chiu JJ
    Cell Signal; 2006 Aug; 18(8):1270-8. PubMed ID: 16310342
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Andrographolide down-regulates hypoxia-inducible factor-1α in human non-small cell lung cancer A549 cells.
    Lin HH; Tsai CW; Chou FP; Wang CJ; Hsuan SW; Wang CK; Chen JH
    Toxicol Appl Pharmacol; 2011 Feb; 250(3):336-45. PubMed ID: 21134392
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells.
    Schnitzer SE; Weigert A; Zhou J; Brüne B
    Mol Cancer Res; 2009 Mar; 7(3):393-401. PubMed ID: 19240180
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interruption of mitochondrial complex IV activity and cytochrome c expression activated O₂·⁻-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R-PI3K-Akt and IGF-1R-PLC γ-PKC pathways.
    Jiang YY; Huang H; Wang HJ; Wu D; Yang R; Tashiro S; Onodera S; Ikejima T
    Eur J Pharmacol; 2011 Oct; 668(1-2):78-87. PubMed ID: 21703257
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhanced antitumor efficacy by blocking activation of the phosphatidylinositol 3-kinase/Akt pathway during anti-angiogenesis therapy.
    Zhao YW; Jin L; Li ZM; Zhao CJ; Wei YQ; Yang HS
    Cancer Sci; 2011 Aug; 102(8):1469-75. PubMed ID: 21561530
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia induces an autocrine-paracrine survival pathway via platelet-derived growth factor (PDGF)-B/PDGF-beta receptor/phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells.
    Zhang SX; Gozal D; Sachleben LR; Rane M; Klein JB; Gozal E
    FASEB J; 2003 Sep; 17(12):1709-11. PubMed ID: 12958184
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Silencing miR-21 sensitizes non-small cell lung cancer A549 cells to ionizing radiation through inhibition of PI3K/Akt.
    Ma Y; Xia H; Liu Y; Li M
    Biomed Res Int; 2014; 2014():617868. PubMed ID: 24804226
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.
    Li CM; Narayanan R; Lu Y; Hurh E; Coss CC; Barrett CM; Miller DD; Dalton JT
    Int J Oncol; 2010 Oct; 37(4):1023-30. PubMed ID: 20811725
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The PI3K/Akt/mTOR pathway mediates retinal progenitor cell survival under hypoxic and superoxide stress.
    Sanghera KP; Mathalone N; Baigi R; Panov E; Wang D; Zhao X; Hsu H; Wang H; Tropepe V; Ward M; Boyd SR
    Mol Cell Neurosci; 2011 Jun; 47(2):145-53. PubMed ID: 21463685
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A synthetic naringenin derivative, 5-hydroxy-7,4'-diacetyloxyflavanone-N-phenyl hydrazone (N101-43), induces apoptosis through up-regulation of Fas/FasL expression and inhibition of PI3K/Akt signaling pathways in non-small-cell lung cancer cells.
    Bak Y; Kim H; Kang JW; Lee DH; Kim MS; Park YS; Kim JH; Jung KY; Lim Y; Hong J; Yoon DY
    J Agric Food Chem; 2011 Sep; 59(18):10286-97. PubMed ID: 21877710
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Formononetin induces cell cycle arrest of human breast cancer cells via IGF1/PI3K/Akt pathways in vitro and in vivo.
    Chen J; Zeng J; Xin M; Huang W; Chen X
    Horm Metab Res; 2011 Sep; 43(10):681-6. PubMed ID: 21932171
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.