217 related articles for article (PubMed ID: 22248819)
1. DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease.
Olkhanud PB; Mughal M; Ayukawa K; Malchinkhuu E; Bodogai M; Feldman N; Rothman S; Lee JH; Chigurupati S; Okun E; Nagashima K; Mattson MP; Biragyn A
Vaccine; 2012 Feb; 30(9):1650-8. PubMed ID: 22248819
[TBL] [Abstract][Full Text] [Related]
2. Prototype Alzheimer's disease vaccine using the immunodominant B cell epitope from beta-amyloid and promiscuous T cell epitope pan HLA DR-binding peptide.
Agadjanyan MG; Ghochikyan A; Petrushina I; Vasilevko V; Movsesyan N; Mkrtichyan M; Saing T; Cribbs DH
J Immunol; 2005 Feb; 174(3):1580-6. PubMed ID: 15661919
[TBL] [Abstract][Full Text] [Related]
3. Strikingly reduced amyloid burden and improved behavioral performance in Alzheimer's disease mice immunized with recombinant chimeric vaccines by hexavalent foldable Aβ₁₋₁₅ fused to toxin-derived carrier proteins.
Yu YZ; Wang WB; Chen A; Chang Q; Liu S; Zhao M; Wang S; Qiu WY; Pang XB; Xu Q; Sun ZW
J Alzheimers Dis; 2014; 41(1):243-60. PubMed ID: 24625800
[TBL] [Abstract][Full Text] [Related]
4. Low concentrations of anti-Aβ antibodies generated in Tg2576 mice by DNA epitope vaccine fused with 3C3d molecular adjuvant do not affect AD pathology.
Movsesyan N; Davtyan H; Mkrtichyan M; Petrushina I; Tiraturyan T; Ross T; Agadjanyan MG; Ghochikyan A; Cribbs DH
Hum Gene Ther; 2010 Nov; 21(11):1569-76. PubMed ID: 20528468
[TBL] [Abstract][Full Text] [Related]
5. Effective DNA epitope chimeric vaccines for Alzheimer's disease using a toxin-derived carrier protein as a molecular adjuvant.
Yu YZ; Wang S; Bai JY; Zhao M; Chen A; Wang WB; Chang Q; Liu S; Qiu WY; Pang XB; Xu Q; Sun ZW
Clin Immunol; 2013 Oct; 149(1):11-24. PubMed ID: 23886550
[TBL] [Abstract][Full Text] [Related]
6. Prophylactic Vaccine Based on Pyroglutamate-3 Amyloid β Generates Strong Antibody Response and Rescues Cognitive Decline in Alzheimer's Disease Model Mice.
Li G; Hu ZW; Chen PG; Sun ZY; Chen YX; Zhao YF; Li YM
ACS Chem Neurosci; 2017 Mar; 8(3):454-459. PubMed ID: 28292186
[TBL] [Abstract][Full Text] [Related]
7. Enhancing Th2 immune responses against amyloid protein by a DNA prime-adenovirus boost regimen for Alzheimer's disease.
Kim HD; Jin JJ; Maxwell JA; Fukuchi K
Immunol Lett; 2007 Sep; 112(1):30-8. PubMed ID: 17686533
[TBL] [Abstract][Full Text] [Related]
8. Immunogenicity, efficacy, safety, and mechanism of action of epitope vaccine (Lu AF20513) for Alzheimer's disease: prelude to a clinical trial.
Davtyan H; Ghochikyan A; Petrushina I; Hovakimyan A; Davtyan A; Poghosyan A; Marleau AM; Movsesyan N; Kiyatkin A; Rasool S; Larsen AK; Madsen PJ; Wegener KM; Ditlevsen DK; Cribbs DH; Pedersen LO; Agadjanyan MG
J Neurosci; 2013 Mar; 33(11):4923-34. PubMed ID: 23486963
[TBL] [Abstract][Full Text] [Related]
9. Nasal inoculation of an adenovirus vector encoding 11 tandem repeats of Abeta1-6 upregulates IL-10 expression and reduces amyloid load in a Mo/Hu APPswe PS1dE9 mouse model of Alzheimer's disease.
Kim HD; Tahara K; Maxwell JA; Lalonde R; Fukuiwa T; Fujihashi K; Van Kampen KR; Kong FK; Tang DC; Fukuchi K
J Gene Med; 2007 Feb; 9(2):88-98. PubMed ID: 17219449
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of a DNA Aβ42 Vaccine in Aged NZW Rabbits: Antibody Kinetics and Immune Profile after Intradermal Immunization with Full-Length DNA Aβ42 Trimer.
Lambracht-Washington D; Fu M; Wight-Carter M; Riegel M; Rosenberg RN
J Alzheimers Dis; 2017; 57(1):97-112. PubMed ID: 28222511
[TBL] [Abstract][Full Text] [Related]
11. Gene vaccination to bias the immune response to amyloid-beta peptide as therapy for Alzheimer disease.
Qu B; Rosenberg RN; Li L; Boyer PJ; Johnston SA
Arch Neurol; 2004 Dec; 61(12):1859-64. PubMed ID: 15596606
[TBL] [Abstract][Full Text] [Related]
12. Maternal antibodies facilitate Amyloid-β clearance by activating Fc-receptor-Syk-mediated phagocytosis.
Illouz T; Nicola R; Ben-Shushan L; Madar R; Biragyn A; Okun E
Commun Biol; 2021 Mar; 4(1):329. PubMed ID: 33712740
[TBL] [Abstract][Full Text] [Related]
13. Prophylactic immunotherapy of Alzheimer's disease using recombinant amyloid-β B-cell epitope chimeric protein as subunit vaccine.
Yu YZ; Xu Q
Hum Vaccin Immunother; 2016 Nov; 12(11):2801-2804. PubMed ID: 27379885
[TBL] [Abstract][Full Text] [Related]
14. Active full-length DNA Aβ
Rosenberg RN; Fu M; Lambracht-Washington D
Alzheimers Res Ther; 2018 Nov; 10(1):115. PubMed ID: 30454039
[TBL] [Abstract][Full Text] [Related]
15. Active immunization with the peptide epitope vaccine Aβ3-10-KLH induces a Th2-polarized anti-Aβ antibody response and decreases amyloid plaques in APP/PS1 transgenic mice.
Ding L; Meng Y; Zhang HY; Yin WC; Yan Y; Cao YP
Neurosci Lett; 2016 Nov; 634():1-6. PubMed ID: 27693663
[TBL] [Abstract][Full Text] [Related]
16. Comparison of Efficacy of Preventive and Therapeutic Vaccines Targeting the N Terminus of β-Amyloid in an Animal Model of Alzheimer's Disease.
Petrushina I; Davtyan H; Hovakimyan A; Davtyan A; Passos GF; Cribbs DH; Ghochikyan A; Agadjanyan MG
Mol Ther; 2017 Jan; 25(1):153-164. PubMed ID: 28129111
[TBL] [Abstract][Full Text] [Related]
17. Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric Abeta species in amyloid precursor protein transgenic mice.
Petrushina I; Ghochikyan A; Mktrichyan M; Mamikonyan G; Movsesyan N; Davtyan H; Patel A; Head E; Cribbs DH; Agadjanyan MG
J Neurosci; 2007 Nov; 27(46):12721-31. PubMed ID: 18003852
[TBL] [Abstract][Full Text] [Related]
18. Norovirus P particle-based active Aβ immunotherapy elicits sufficient immunogenicity and improves cognitive capacity in a mouse model of Alzheimer's disease.
Fu L; Li Y; Hu Y; Zheng Y; Yu B; Zhang H; Wu J; Wu H; Yu X; Kong W
Sci Rep; 2017 Jan; 7():41041. PubMed ID: 28106117
[TBL] [Abstract][Full Text] [Related]
19. Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials.
Petrushina I; Hovakimyan A; Harahap-Carrillo IS; Davtyan H; Antonyan T; Chailyan G; Kazarian K; Antonenko M; Jullienne A; Hamer MM; Obenaus A; King O; Zagorski K; Blurton-Jones M; Cribbs DH; Lander H; Ghochikyan A; Agadjanyan MG
Neurobiol Dis; 2020 Jun; 139():104823. PubMed ID: 32119976
[TBL] [Abstract][Full Text] [Related]
20. Alzheimer's disease Advax(CpG)- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological molecules.
Davtyan H; Zagorski K; Rajapaksha H; Hovakimyan A; Davtyan A; Petrushina I; Kazarian K; Cribbs DH; Petrovsky N; Agadjanyan MG; Ghochikyan A
Sci Rep; 2016 Jul; 6():28912. PubMed ID: 27363809
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
