BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 22249853)

  • 1. Substitution of the catalytic metal and protein PEGylation enhances activity and stability of bacterial phosphotriesterase.
    Perezgasga L; Sánchez-Sánchez L; Aguila S; Vazquez-Duhalt R
    Appl Biochem Biotechnol; 2012 Mar; 166(5):1236-47. PubMed ID: 22249853
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preparation and characterization of methoxy polyethylene glycol-conjugated phosphotriesterase as a potential catalytic bioscavenger against organophosphate poisoning.
    Jun D; Musilová L; Link M; Loiodice M; Nachon F; Rochu D; Renault F; Masson P
    Chem Biol Interact; 2010 Sep; 187(1-3):380-3. PubMed ID: 20230809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evolution in the amidohydrolase superfamily: substrate-assisted gain of function in the E183K mutant of a phosphotriesterase-like metal-carboxylesterase.
    Mandrich L; Manco G
    Biochemistry; 2009 Jun; 48(24):5602-12. PubMed ID: 19438255
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Directed evolution of phosphotriesterase from Pseudomonas diminuta for heterologous expression in Escherichia coli results in stabilization of the metal-free state.
    Roodveldt C; Tawfik DS
    Protein Eng Des Sel; 2005 Jan; 18(1):51-8. PubMed ID: 15790580
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis.
    Ely F; Hadler KS; Gahan LR; Guddat LW; Ollis DL; Schenk G
    Biochem J; 2010 Dec; 432(3):565-73. PubMed ID: 20868365
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced refoldability and thermoactivity of fluorinated phosphotriesterase.
    Baker PJ; Montclare JK
    Chembiochem; 2011 Aug; 12(12):1845-8. PubMed ID: 21710682
    [No Abstract]   [Full Text] [Related]  

  • 7. Quantum dot display enhances activity of a phosphotriesterase trimer.
    Breger JC; Walper SA; Oh E; Susumu K; Stewart MH; Deschamps JR; Medintz IL
    Chem Commun (Camb); 2015 Apr; 51(29):6403-6. PubMed ID: 25764989
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Contribution of the active-site metal cation to the catalytic activity and to the conformational stability of phosphotriesterase: temperature- and pH-dependence.
    Rochu D; Viguié N; Renault F; Crouzier D; Froment MT; Masson P
    Biochem J; 2004 Jun; 380(Pt 3):627-33. PubMed ID: 15018612
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter.
    Ely F; Pedroso MM; Gahan LR; Ollis DL; Guddat LW; Schenk G
    J Inorg Biochem; 2012 Jan; 106(1):19-22. PubMed ID: 22112835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The reaction mechanism of paraoxon hydrolysis by phosphotriesterase from combined QM/MM simulations.
    Wong KY; Gao J
    Biochemistry; 2007 Nov; 46(46):13352-69. PubMed ID: 17966992
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Improved stability and half-life of fluorinated phosphotriesterase using Rosetta.
    Yang CY; Renfrew PD; Olsen AJ; Zhang M; Yuvienco C; Bonneau R; Montclare JK
    Chembiochem; 2014 Aug; 15(12):1761-4. PubMed ID: 25066940
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily.
    Xiang DF; Kolb P; Fedorov AA; Meier MM; Fedorov LV; Nguyen TT; Sterner R; Almo SC; Shoichet BK; Raushel FM
    Biochemistry; 2009 Mar; 48(10):2237-47. PubMed ID: 19159332
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans.
    Hawwa R; Larsen SD; Ratia K; Mesecar AD
    J Mol Biol; 2009 Oct; 393(1):36-57. PubMed ID: 19631223
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure of a Novel Phosphotriesterase from Sphingobium sp. TCM1: A Familiar Binuclear Metal Center Embedded in a Seven-Bladed β-Propeller Protein Fold.
    Mabanglo MF; Xiang DF; Bigley AN; Raushel FM
    Biochemistry; 2016 Jul; 55(28):3963-74. PubMed ID: 27353520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased expression of a bacterial phosphotriesterase in Escherichia coli through directed evolution.
    McLoughlin SY; Jackson C; Liu JW; Ollis D
    Protein Expr Purif; 2005 Jun; 41(2):433-40. PubMed ID: 15866732
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus.
    Hawwa R; Aikens J; Turner RJ; Santarsiero BD; Mesecar AD
    Arch Biochem Biophys; 2009 Aug; 488(2):109-20. PubMed ID: 19615330
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Theoretical study of the phosphotriesterase reaction mechanism.
    Chen SL; Fang WH; Himo F
    J Phys Chem B; 2007 Feb; 111(6):1253-5. PubMed ID: 17253743
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism.
    Jackson C; Kim HK; Carr PD; Liu JW; Ollis DL
    Biochim Biophys Acta; 2005 Aug; 1752(1):56-64. PubMed ID: 16054447
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-based rational design of a phosphotriesterase.
    Jackson CJ; Weir K; Herlt A; Khurana J; Sutherland TD; Horne I; Easton C; Russell RJ; Scott C; Oakeshott JG
    Appl Environ Microbiol; 2009 Aug; 75(15):5153-6. PubMed ID: 19502439
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hyperthermophilic phosphotriesterases/lactonases for the environment and human health.
    Mandrich L; Merone L; Manco G
    Environ Technol; 2010 Sep; 31(10):1115-27. PubMed ID: 20718294
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.