435 related articles for article (PubMed ID: 22252297)
1. Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation.
Yoshida H; Kimura A; Fukaya T; Sekiya T; Morita R; Shichita T; Inoue H; Yoshimura A
Biochem Biophys Res Commun; 2012 Feb; 418(2):234-40. PubMed ID: 22252297
[TBL] [Abstract][Full Text] [Related]
2. Pyridone 6, a pan-JAK inhibitor, ameliorates allergic skin inflammation of NC/Nga mice via suppression of Th2 and enhancement of Th17.
Nakagawa R; Yoshida H; Asakawa M; Tamiya T; Inoue N; Morita R; Inoue H; Nakao A; Yoshimura A
J Immunol; 2011 Nov; 187(9):4611-20. PubMed ID: 21957150
[TBL] [Abstract][Full Text] [Related]
3. Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition.
Telliez JB; Dowty ME; Wang L; Jussif J; Lin T; Li L; Moy E; Balbo P; Li W; Zhao Y; Crouse K; Dickinson C; Symanowicz P; Hegen M; Banker ME; Vincent F; Unwalla R; Liang S; Gilbert AM; Brown MF; Hayward M; Montgomery J; Yang X; Bauman J; Trujillo JI; Casimiro-Garcia A; Vajdos FF; Leung L; Geoghegan KF; Quazi A; Xuan D; Jones L; Hett E; Wright K; Clark JD; Thorarensen A
ACS Chem Biol; 2016 Dec; 11(12):3442-3451. PubMed ID: 27791347
[TBL] [Abstract][Full Text] [Related]
4. CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice.
Yoshida H; Kotani H; Kondo T; Tani I; Wei X; Tsuruta S; Kimura A; Asakawa M; Ito M; Nagai S; Yoshimura A
Biochem Biophys Res Commun; 2013 Jun; 435(3):378-84. PubMed ID: 23665028
[TBL] [Abstract][Full Text] [Related]
5. Suppression of human and mouse Th17 differentiation and autoimmunity by an endogenous Interleukin 23 receptor cytokine-binding homology region.
Guo W; Luo C; Wang C; Wang YH; Wang X; Gao XD; Yao WB
Int J Biochem Cell Biol; 2014 Oct; 55():304-10. PubMed ID: 25263529
[TBL] [Abstract][Full Text] [Related]
6. The JAK inhibitor CP-690,550 (tofacitinib) inhibits TNF-induced chemokine expression in fibroblast-like synoviocytes: autocrine role of type I interferon.
Rosengren S; Corr M; Firestein GS; Boyle DL
Ann Rheum Dis; 2012 Mar; 71(3):440-7. PubMed ID: 22121136
[TBL] [Abstract][Full Text] [Related]
7. 1,25 Dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNgamma axis leading to Th1 response in experimental allergic encephalomyelitis.
Muthian G; Raikwar HP; Rajasingh J; Bright JJ
J Neurosci Res; 2006 May; 83(7):1299-309. PubMed ID: 16547967
[TBL] [Abstract][Full Text] [Related]
8. JAK2-STAT3 blockade by AG490 suppresses autoimmune arthritis in mice via reciprocal regulation of regulatory T Cells and Th17 cells.
Park JS; Lee J; Lim MA; Kim EK; Kim SM; Ryu JG; Lee JH; Kwok SK; Park KS; Kim HY; Park SH; Cho ML
J Immunol; 2014 May; 192(9):4417-24. PubMed ID: 24688026
[TBL] [Abstract][Full Text] [Related]
9. A novel JAK-STAT inhibitor, 2-[(3-Carbamoyl-2-thienyl)amino]-2-oxoethyl(2,6-dichlorophenyl)acetate, suppresses helper T cell differentiation in vitro and collagen-induced arthritis in vivo.
Asakawa M; Yoshida H; Sakai R; Saeki K; Okada M; Kanamori M; Kotani H; Wei X; Yoshimura A
Biochem Biophys Res Commun; 2015 Dec; 468(4):766-73. PubMed ID: 26562526
[TBL] [Abstract][Full Text] [Related]
10. Tyrphostin B42 inhibits IL-12-induced tyrosine phosphorylation and activation of Janus kinase-2 and prevents experimental allergic encephalomyelitis.
Bright JJ; Du C; Sriram S
J Immunol; 1999 May; 162(10):6255-62. PubMed ID: 10229872
[TBL] [Abstract][Full Text] [Related]
11. Interferon-γ orchestrates the number and function of Th17 cells in experimental autoimmune encephalomyelitis.
Berghmans N; Nuyts A; Uyttenhove C; Van Snick J; Opdenakker G; Heremans H
J Interferon Cytokine Res; 2011 Jul; 31(7):575-87. PubMed ID: 21348780
[TBL] [Abstract][Full Text] [Related]
12. Dehydrodiconiferyl alcohol (DHCA) modulates the differentiation of Th17 and Th1 cells and suppresses experimental autoimmune encephalomyelitis.
Lee J; Choi J; Lee W; Ko K; Kim S
Mol Immunol; 2015 Dec; 68(2 Pt B):434-44. PubMed ID: 26477735
[TBL] [Abstract][Full Text] [Related]
13. A novel human truncated IL12rβ1-Fc fusion protein ameliorates experimental autoimmune encephalomyelitis via specific binding of p40 to inhibit Th1 and Th17 cell differentiation.
Guo W; Wang C; Wang X; Luo C; Yu D; Wang Y; Chen Y; Lei W; Gao X; Yao W
Oncotarget; 2015 Oct; 6(30):28539-55. PubMed ID: 26384304
[TBL] [Abstract][Full Text] [Related]
14. Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads.
Tanaka K; Ichiyama K; Hashimoto M; Yoshida H; Takimoto T; Takaesu G; Torisu T; Hanada T; Yasukawa H; Fukuyama S; Inoue H; Nakanishi Y; Kobayashi T; Yoshimura A
J Immunol; 2008 Mar; 180(6):3746-56. PubMed ID: 18322180
[TBL] [Abstract][Full Text] [Related]
15. Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).
Ghoreschi K; Jesson MI; Li X; Lee JL; Ghosh S; Alsup JW; Warner JD; Tanaka M; Steward-Tharp SM; Gadina M; Thomas CJ; Minnerly JC; Storer CE; LaBranche TP; Radi ZA; Dowty ME; Head RD; Meyer DM; Kishore N; O'Shea JJ
J Immunol; 2011 Apr; 186(7):4234-43. PubMed ID: 21383241
[TBL] [Abstract][Full Text] [Related]
16. Total glucosides of paeony inhibits Th1/Th17 cells via decreasing dendritic cells activation in rheumatoid arthritis.
Lin J; Xiao L; Ouyang G; Shen Y; Huo R; Zhou Z; Sun Y; Zhu X; Zhang J; Shen B; Li N
Cell Immunol; 2012 Dec; 280(2):156-63. PubMed ID: 23399842
[TBL] [Abstract][Full Text] [Related]
17. Invariant NKT cells producing IL-4 or IL-10, but not IFN-gamma, inhibit the Th1 response in experimental autoimmune encephalomyelitis, whereas none of these cells inhibits the Th17 response.
Oh SJ; Chung DH
J Immunol; 2011 Jun; 186(12):6815-21. PubMed ID: 21572032
[TBL] [Abstract][Full Text] [Related]
18. Tetrandrine, an agonist of aryl hydrocarbon receptor, reciprocally modulates the activities of STAT3 and STAT5 to suppress Th17 cell differentiation.
Yuan X; Dou Y; Wu X; Wei Z; Dai Y
J Cell Mol Med; 2017 Sep; 21(9):2172-2183. PubMed ID: 28332288
[TBL] [Abstract][Full Text] [Related]
19. IL-10-producing regulatory B10 cells ameliorate collagen-induced arthritis via suppressing Th17 cell generation.
Yang M; Deng J; Liu Y; Ko KH; Wang X; Jiao Z; Wang S; Hua Z; Sun L; Srivastava G; Lau CS; Cao X; Lu L
Am J Pathol; 2012 Jun; 180(6):2375-85. PubMed ID: 22538089
[TBL] [Abstract][Full Text] [Related]
20. Estrogen receptor α signaling in T lymphocytes is required for estradiol-mediated inhibition of Th1 and Th17 cell differentiation and protection against experimental autoimmune encephalomyelitis.
Lélu K; Laffont S; Delpy L; Paulet PE; Périnat T; Tschanz SA; Pelletier L; Engelhardt B; Guéry JC
J Immunol; 2011 Sep; 187(5):2386-93. PubMed ID: 21810607
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]