BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 2225231)

  • 1. Differences in sequence selectivity of DNA alkylation by isomeric intercalating aniline mustards.
    Prakash AS; Denny WA; Wakelin LP
    Chem Biol Interact; 1990; 76(2):241-8. PubMed ID: 2225231
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
    McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
    Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA-directed alkylating ligands as potential antitumor agents: sequence specificity of alkylation by intercalating aniline mustards.
    Prakash AS; Denny WA; Gourdie TA; Valu KK; Woodgate PD; Wakelin LP
    Biochemistry; 1990 Oct; 29(42):9799-807. PubMed ID: 2271617
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aniline mustard analogues of the DNA-intercalating agent amsacrine: DNA interaction and biological activity.
    Fan JY; Valu KK; Woodgate PD; Baguley BC; Denny WA
    Anticancer Drug Des; 1997 Apr; 12(3):181-203. PubMed ID: 9154110
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of the major lesion from the reaction of an acridine-targeted aniline mustard with DNA as an adenine N1 adduct.
    Boritzki TJ; Palmer BD; Coddington JM; Denny WA
    Chem Res Toxicol; 1994; 7(1):41-6. PubMed ID: 8155823
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of DNA-targeted spatially separated bis(aniline mustards) as potential alkylating agents with enhanced DNA cross-linking capability.
    Gourdie TA; Prakash AS; Wakelin LP; Woodgate PD; Denny WA
    J Med Chem; 1991 Jan; 34(1):240-8. PubMed ID: 1992124
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA-directed aniline mustards based on 9-aminoacridine: interaction with DNA.
    O'Connor CJ; Denny WA; Fan JY; Gamage RS
    Chem Biol Interact; 1992 Nov; 85(1):1-14. PubMed ID: 1458547
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA-directed alkylating agents. 3. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the length of the linker chain.
    Valu KK; Gourdie TA; Boritzki TJ; Gravatt GL; Baguley BC; Wilson WR; Wakelin LP; Woodgate PD; Denny WA
    J Med Chem; 1990 Nov; 33(11):3014-9. PubMed ID: 2231599
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard.
    Gourdie TA; Valu KK; Gravatt GL; Boritzki TJ; Baguley BC; Wakelin LP; Wilson WR; Woodgate PD; Denny WA
    J Med Chem; 1990 Apr; 33(4):1177-86. PubMed ID: 2319563
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.
    Mattes WB; Hartley JA; Kohn KW
    Nucleic Acids Res; 1986 Apr; 14(7):2971-87. PubMed ID: 3960738
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Microbial mutagenic effects of the DNA minor groove binder pibenzimol (Hoechst 33258) and a series of mustard analogues.
    Ferguson LR; Denny WA
    Mutat Res; 1995 Jun; 329(1):19-27. PubMed ID: 7539521
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA-directed aniline mustards with high selectivity for adenine or guanine bases: mutagenesis in a variety of Salmonella typhimurium strains differing in DNA-repair capability.
    Ferguson LR; Denny WA; Boritzki TJ
    Mutat Res; 1994 Apr; 321(1-2):27-34. PubMed ID: 7510842
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and DNA-sequence selectivity of a series of mono- and difunctional 9-aminoacridine nitrogen mustards.
    Kohn KW; Orr A; O'Connor PM; Guziec LJ; Guziec FS
    J Med Chem; 1994 Jan; 37(1):67-72. PubMed ID: 8289202
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA-binding properties and antitumour activity of monofunctional alkylating groups attached to the DNA-intercalating chromophore phenanthridine: n-bromoalkylphenanthridinium bromides.
    Wickham G; Prakash AS; Wakelin LP; McFadyen WD
    Biochim Biophys Acta; 1991 Apr; 1073(3):528-37. PubMed ID: 2015276
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sequence specificity of DNA alkylation by the antitumor natural product leinamycin.
    Zang H; Gates KS
    Chem Res Toxicol; 2003 Dec; 16(12):1539-46. PubMed ID: 14680367
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA sequence selectivity of guanine-N7 alkylation by three antitumor chloroethylating agents.
    Hartley JA; Gibson NW; Kohn KW; Mattes WB
    Cancer Res; 1986 Apr; 46(4 Pt 2):1943-7. PubMed ID: 3004713
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
    Smaill JB; Fan JY; Denny WA
    Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The cytotoxicity, DNA crosslinking ability and DNA sequence selectivity of the aniline mustards melphalan, chlorambucil and 4-[bis(2-chloroethyl)amino] benzoic acid.
    Sunters A; Springer CJ; Bagshawe KD; Souhami RL; Hartley JA
    Biochem Pharmacol; 1992 Jul; 44(1):59-64. PubMed ID: 1632839
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.
    Kapuriya N; Kapuriya K; Zhang X; Chou TC; Kakadiya R; Wu YT; Tsai TH; Chen YT; Lee TC; Shah A; Naliapara Y; Su TL
    Bioorg Med Chem; 2008 May; 16(10):5413-23. PubMed ID: 18450456
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin.
    Broggini M; Coley HM; Mongelli N; Pesenti E; Wyatt MD; Hartley JA; D'Incalci M
    Nucleic Acids Res; 1995 Jan; 23(1):81-7. PubMed ID: 7870593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.