BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 22252525)

  • 1. PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation.
    Qing H; Gong W; Che Y; Wang X; Peng L; Liang Y; Wang W; Deng Q; Zhang H; Jiang B
    Tumour Biol; 2012 Aug; 33(4):985-94. PubMed ID: 22252525
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber formation, migration, and proliferation and injury-induced vascular wall remodeling.
    Kundumani-Sridharan V; Singh NK; Kumar S; Gadepalli R; Rao GN
    J Biol Chem; 2013 Jul; 288(30):22150-62. PubMed ID: 23737530
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis.
    Kan WL; Yin C; Xu HX; Xu G; To KK; Cho CH; Rudd JA; Lin G
    Int J Cancer; 2013 Feb; 132(3):707-16. PubMed ID: 22733377
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BEX2 promotes tumor proliferation in colorectal cancer.
    Hu Y; Xiao Q; Chen H; He J; Tan Y; Liu Y; Wang Z; Yang Q; Shen X; Huang Y; Yuan Y; Ding K
    Int J Biol Sci; 2017; 13(3):286-294. PubMed ID: 28367093
    [TBL] [Abstract][Full Text] [Related]  

  • 5. P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation.
    Ching YP; Leong VY; Lee MF; Xu HT; Jin DY; Ng IO
    Cancer Res; 2007 Apr; 67(8):3601-8. PubMed ID: 17440071
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Knockdown of REG Iα Enhances the Sensitivity to 5-Fluorouracil of Colorectal Cancer Cells via Cyclin D1/CDK4 Pathway and BAX/BCL-2 Pathways.
    Wang Y; Liu X; Liu J; Zhang T
    Cancer Biother Radiopharm; 2019 Aug; 34(6):362-370. PubMed ID: 30973271
    [No Abstract]   [Full Text] [Related]  

  • 7. PAK1 overexpression promotes cell proliferation in cutaneous T cell lymphoma via suppression of PUMA and p21.
    Wang Y; Gu X; Li W; Zhang Q; Zhang C
    J Dermatol Sci; 2018 Apr; 90(1):60-67. PubMed ID: 29307600
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Up-regulation of stem cell markers by P21-activated kinase 1 contributes to 5-fluorouracil resistance of colorectal cancer.
    Huynh N; Shulkes A; Baldwin G; He H
    Cancer Biol Ther; 2016 Aug; 17(8):813-23. PubMed ID: 27260988
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p21-activated protein kinase 1 induces the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2.
    Li LH; Wu GY; Lu YZ; Chen XH; Liu BY; Zheng MH; Cai JC
    Oncol Rep; 2017 Jul; 38(1):193-200. PubMed ID: 28534988
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway.
    Wang SY; Gao K; Deng DL; Cai JJ; Xiao ZY; He LQ; Jiao HL; Ye YP; Yang RW; Li TT; Liang L; Liao WT; Ding YQ
    Oncotarget; 2016 Jan; 7(3):2878-88. PubMed ID: 26701208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and -resistant colorectal cancer cells.
    Wen C; Chen J; Zhang D; Wang H; Che J; Qin Q; He L; Cai Z; Lin M; Lou Q; Huang L; Chen D; Iwamoto A; Ren D; Wang L; Lan P; Wang J; Liu H; Yang X
    Cancer Lett; 2016 Dec; 383(2):295-308. PubMed ID: 27713084
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ROS/JNK/c-Jun axis is involved in oridonin-induced caspase-dependent apoptosis in human colorectal cancer cells.
    Zhang D; Zhou Q; Huang D; He L; Zhang H; Hu B; Peng H; Ren D
    Biochem Biophys Res Commun; 2019 Jun; 513(3):594-601. PubMed ID: 30981511
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of PAK1 gene silencing on proliferation and apoptosis in hepatocellular carcinoma cell lines MHCC97-H and HepG2 and cells in xenograft tumor.
    Zhang ZL; Liu GC; Peng L; Zhang C; Jia YM; Yang WH; Mao L
    Gene Ther; 2018 Jul; 25(4):284-296. PubMed ID: 29802374
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Downregulation of cyclin D1-CDK4 protein in human embryonic lung fibroblasts (HELF) induced by silica is mediated through the ERK and JNK pathway.
    Shen F; Fan X; Liu B; Jia X; Gao A; Du H; Ye M; You B; Huang C; Shi X
    Cell Biol Int; 2008 Oct; 32(10):1284-92. PubMed ID: 18703151
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.
    Ong CC; Gierke S; Pitt C; Sagolla M; Cheng CK; Zhou W; Jubb AM; Strickland L; Schmidt M; Duron SG; Campbell DA; Zheng W; Dehdashti S; Shen M; Yang N; Behnke ML; Huang W; McKew JC; Chernoff J; Forrest WF; Haverty PM; Chin SF; Rakha EA; Green AR; Ellis IO; Caldas C; O'Brien T; Friedman LS; Koeppen H; Rudolph J; Hoeflich KP
    Breast Cancer Res; 2015 Apr; 17(1):59. PubMed ID: 25902869
    [TBL] [Abstract][Full Text] [Related]  

  • 16. P21-activated protein kinase 1 is overexpressed in gastric cancer and induces cancer metastasis.
    Li LH; Luo Q; Zheng MH; Pan C; Wu GY; Lu YZ; Feng B; Chen XH; Liu BY
    Oncol Rep; 2012 May; 27(5):1435-42. PubMed ID: 22293972
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis.
    Chung JH; Eng C
    Cancer Res; 2005 Sep; 65(18):8096-100. PubMed ID: 16166282
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.
    Liao YJ; Bai HY; Li ZH; Zou J; Chen JW; Zheng F; Zhang JX; Mai SJ; Zeng MS; Sun HD; Pu JX; Xie D
    Cell Death Dis; 2014 Mar; 5(3):e1137. PubMed ID: 24651440
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Essential oil of Pinus koraiensis inhibits cell proliferation and migration via inhibition of p21-activated kinase 1 pathway in HCT116 colorectal cancer cells.
    Cho SM; Lee EO; Kim SH; Lee HJ
    BMC Complement Altern Med; 2014 Jul; 14():275. PubMed ID: 25074784
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aldolase A promotes proliferation and G
    Fu H; Gao H; Qi X; Zhao L; Wu D; Bai Y; Li H; Liu X; Hu J; Shao S
    Cancer Commun (Lond); 2018 May; 38(1):18. PubMed ID: 29764507
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.