327 related articles for article (PubMed ID: 22257012)
1. Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1.
Shabanpoor F; Akhter Hossain M; Ryan PJ; Belgi A; Layfield S; Kocan M; Zhang S; Samuel CS; Gundlach AL; Bathgate RA; Separovic F; Wade JD
J Med Chem; 2012 Feb; 55(4):1671-81. PubMed ID: 22257012
[TBL] [Abstract][Full Text] [Related]
2. Probing the functional domains of relaxin-3 and the creation of a selective antagonist for RXFP3/GPCR135 over relaxin receptor RXFP1/LGR7.
Liu C; Kuei C; Sutton S; Shelton J; Zhu J; Nepomuceno D; Hossain MA; Wade JD; Bathgate RA; Bonaventure P; Lovenberg T
Ann N Y Acad Sci; 2009 Apr; 1160():31-7. PubMed ID: 19416155
[TBL] [Abstract][Full Text] [Related]
3. The relaxin family peptide receptor 3 activates extracellular signal-regulated kinase 1/2 through a protein kinase C-dependent mechanism.
van der Westhuizen ET; Werry TD; Sexton PM; Summers RJ
Mol Pharmacol; 2007 Jun; 71(6):1618-29. PubMed ID: 17351017
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3.
Haugaard-Kedström LM; Shabanpoor F; Hossain MA; Clark RJ; Ryan PJ; Craik DJ; Gundlach AL; Wade JD; Bathgate RA; Rosengren KJ
J Am Chem Soc; 2011 Apr; 133(13):4965-74. PubMed ID: 21384867
[TBL] [Abstract][Full Text] [Related]
5. H2 relaxin is a biased ligand relative to H3 relaxin at the relaxin family peptide receptor 3 (RXFP3).
van der Westhuizen ET; Christopoulos A; Sexton PM; Wade JD; Summers RJ
Mol Pharmacol; 2010 May; 77(5):759-72. PubMed ID: 20159943
[TBL] [Abstract][Full Text] [Related]
6. Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration.
DeChristopher B; Park SH; Vong L; Bamford D; Cho HH; Duvadie R; Fedolak A; Hogan C; Honda T; Pandey P; Rozhitskaya O; Su L; Tomlinson E; Wallace I
Bioorg Med Chem Lett; 2019 Apr; 29(8):991-994. PubMed ID: 30824200
[TBL] [Abstract][Full Text] [Related]
7. Addition of a carboxy-terminal green fluorescent protein does not alter the binding and signaling properties of relaxin family Peptide receptor 3.
van der Westhuizen ET; Wade JD; Sexton PM; Summers RJ
Ann N Y Acad Sci; 2009 Apr; 1160():105-7. PubMed ID: 19416168
[TBL] [Abstract][Full Text] [Related]
8. Differential effects of relaxin-3 and a selective relaxin-3 receptor agonist on food and water intake and hypothalamic neuronal activity in rats.
de Ávila C; Chometton S; Lenglos C; Calvez J; Gundlach AL; Timofeeva E
Behav Brain Res; 2018 Jan; 336():135-144. PubMed ID: 28864207
[TBL] [Abstract][Full Text] [Related]
9. The structural and functional role of the B-chain C-terminal arginine in the relaxin-3 peptide antagonist, R3(BDelta23-27)R/I5.
Hossain MA; Bathgate RA; Rosengren KJ; Shabanpoor F; Zhang S; Lin F; Tregear GW; Wade JD
Chem Biol Drug Des; 2009 Jan; 73(1):46-52. PubMed ID: 19152634
[TBL] [Abstract][Full Text] [Related]
10. Development of a selective agonist for relaxin family peptide receptor 3.
Wei D; Hu MJ; Shao XX; Wang JH; Nie WH; Liu YL; Xu ZG; Guo ZY
Sci Rep; 2017 Jun; 7(1):3230. PubMed ID: 28607363
[TBL] [Abstract][Full Text] [Related]
11. Central relaxin-3 receptor (RXFP3) activation decreases anxiety- and depressive-like behaviours in the rat.
Ryan PJ; Büchler E; Shabanpoor F; Hossain MA; Wade JD; Lawrence AJ; Gundlach AL
Behav Brain Res; 2013 May; 244():142-51. PubMed ID: 23380674
[TBL] [Abstract][Full Text] [Related]
12. Relaxin peptide hormones are protective during the early stages of ischemic stroke in male rats.
Bergeron LH; Willcox JM; Alibhai FJ; Connell BJ; Saleh TM; Wilson BC; Summerlee AJ
Endocrinology; 2015 Feb; 156(2):638-46. PubMed ID: 25456068
[TBL] [Abstract][Full Text] [Related]
13. Structure and activity in the relaxin family of peptides.
Tregear GW; Bathgate RA; Hossain MA; Lin F; Zhang S; Shabanpoor F; Scott DJ; Ma S; Gundlach AL; Samuel CS; Wade JD
Ann N Y Acad Sci; 2009 Apr; 1160():5-10. PubMed ID: 19416150
[TBL] [Abstract][Full Text] [Related]
14. Relaxin family peptide receptors--former orphans reunite with their parent ligands to activate multiple signalling pathways.
Halls ML; van der Westhuizen ET; Bathgate RA; Summers RJ
Br J Pharmacol; 2007 Mar; 150(6):677-91. PubMed ID: 17293890
[TBL] [Abstract][Full Text] [Related]
15. The electrostatic interactions of relaxin-3 with receptor RXFP4 and the influence of its B-chain C-terminal conformation.
Wang XY; Guo YQ; Zhang WJ; Shao XX; Liu YL; Xu ZG; Guo ZY
FEBS J; 2014 Jul; 281(13):2927-36. PubMed ID: 24802387
[TBL] [Abstract][Full Text] [Related]
16. International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides.
Bathgate RA; Ivell R; Sanborn BM; Sherwood OD; Summers RJ
Pharmacol Rev; 2006 Mar; 58(1):7-31. PubMed ID: 16507880
[TBL] [Abstract][Full Text] [Related]
17. Chimeric relaxin peptides highlight the role of the A-chain in the function of H2 relaxin.
Hossain MA; Wade JD; Bathgate RA
Peptides; 2012 May; 35(1):102-6. PubMed ID: 22414484
[TBL] [Abstract][Full Text] [Related]
18. Chemically synthesized dicarba H2 relaxin analogues retain strong RXFP1 receptor activity but show an unexpected loss of in vitro serum stability.
Hossain MA; Haugaard-Kedström LM; Rosengren KJ; Bathgate RA; Wade JD
Org Biomol Chem; 2015 Nov; 13(44):10895-903. PubMed ID: 26368576
[TBL] [Abstract][Full Text] [Related]
19. Increased feeding and body weight gain in rats after acute and chronic activation of RXFP3 by relaxin-3 and receptor-selective peptides: functional and therapeutic implications.
Ganella DE; Ryan PJ; Bathgate RA; Gundlach AL
Behav Pharmacol; 2012 Sep; 23(5-6):516-25. PubMed ID: 22854307
[TBL] [Abstract][Full Text] [Related]
20. Partial agonist activity of R3(BΔ23-27)R/I5 at RXFP3--investigation of in vivo and in vitro pharmacology.
Kristensson L; Mayer G; Ploj K; Wetterlund M; Arlbrandt S; Björquist A; Wissing BM; Castaldo M; Larsson N
Eur J Pharmacol; 2015 Jan; 747():123-31. PubMed ID: 25496752
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
