163 related articles for article (PubMed ID: 22257095)
1. 3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A₂B adenosine receptor antagonists.
Taliani S; Pugliesi I; Barresi E; Simorini F; Salerno S; La Motta C; Marini AM; Cosimelli B; Cosconati S; Di Maro S; Marinelli L; Daniele S; Trincavelli ML; Greco G; Novellino E; Martini C; Da Settimo F
J Med Chem; 2012 Feb; 55(4):1490-9. PubMed ID: 22257095
[TBL] [Abstract][Full Text] [Related]
2. Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists.
Baraldi PG; Baraldi S; Saponaro G; Preti D; Romagnoli R; Piccagli L; Cavalli A; Recanatini M; Moorman AR; Zaid AN; Varani K; Borea PA; Tabrizi MA
J Med Chem; 2012 Jan; 55(2):797-811. PubMed ID: 22148859
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.
Baraldi PG; Tabrizi MA; Preti D; Bovero A; Romagnoli R; Fruttarolo F; Zaid NA; Moorman AR; Varani K; Gessi S; Merighi S; Borea PA
J Med Chem; 2004 Mar; 47(6):1434-47. PubMed ID: 14998332
[TBL] [Abstract][Full Text] [Related]
4. 3-(Fur-2-yl)-10-(2-phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one, a novel adenosine receptor antagonist with A(2A)-mediated neuroprotective effects.
Scatena A; Fornai F; Trincavelli ML; Taliani S; Daniele S; Pugliesi I; Cosconati S; Martini C; Da Settimo F
ACS Chem Neurosci; 2011 Sep; 2(9):526-35. PubMed ID: 22860174
[TBL] [Abstract][Full Text] [Related]
5. Toward PET imaging of A2B adenosine receptors: a carbon-11 labeled triazinobenzimidazole tracer: Synthesis and imaging of a new A2B PET tracer.
Petroni D; Giacomelli C; Taliani S; Barresi E; Robello M; Daniele S; Bartoli A; Burchielli S; Pardini S; Salvadori PA; Da Settimo F; Martini C; Trincavelli ML; Menichetti L
Nucl Med Biol; 2016 May; 43(5):309-17. PubMed ID: 27150034
[TBL] [Abstract][Full Text] [Related]
6. 5-amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a versatile scaffold to obtain potent and selective A3 adenosine receptor antagonists.
Da Settimo F; Primofiore G; Taliani S; Marini AM; La Motta C; Simorini F; Salerno S; Sergianni V; Tuccinardi T; Martinelli A; Cosimelli B; Greco G; Novellino E; Ciampi O; Trincavelli ML; Martini C
J Med Chem; 2007 Nov; 50(23):5676-84. PubMed ID: 17927167
[TBL] [Abstract][Full Text] [Related]
7. New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Baraldi PG; Preti D; Zaid AN; Saponaro G; Tabrizi MA; Baraldi S; Romagnoli R; Moorman AR; Varani K; Cosconati S; Di Maro S; Marinelli L; Novellino E; Borea PA
J Med Chem; 2011 Jul; 54(14):5205-20. PubMed ID: 21675777
[TBL] [Abstract][Full Text] [Related]
8. 1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships.
Stefanachi A; Nicolotti O; Leonetti F; Cellamare S; Campagna F; Loza MI; Brea JM; Mazza F; Gavuzzo E; Carotti A
Bioorg Med Chem; 2008 Nov; 16(22):9780-9. PubMed ID: 18938084
[TBL] [Abstract][Full Text] [Related]
9. Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A
Barresi E; Giacomelli C; Daniele S; Tonazzini I; Robello M; Salerno S; Piano I; Cosimelli B; Greco G; Da Settimo F; Martini C; Trincavelli ML; Taliani S
Bioorg Med Chem; 2018 Dec; 26(22):5885-5895. PubMed ID: 30415894
[TBL] [Abstract][Full Text] [Related]
10. Benzothiazinones: a novel class of adenosine receptor antagonists structurally unrelated to xanthine and adenine derivatives.
Gütschow M; Schlenk M; Gäb J; Paskaleva M; Alnouri MW; Scolari S; Iqbal J; Müller CE
J Med Chem; 2012 Apr; 55(7):3331-41. PubMed ID: 22409573
[TBL] [Abstract][Full Text] [Related]
11. Novel N2-substituted pyrazolo[3,4-d]pyrimidine adenosine A3 receptor antagonists: inhibition of A3-mediated human glioblastoma cell proliferation.
Taliani S; La Motta C; Mugnaini L; Simorini F; Salerno S; Marini AM; Da Settimo F; Cosconati S; Cosimelli B; Greco G; Limongelli V; Marinelli L; Novellino E; Ciampi O; Daniele S; Trincavelli ML; Martini C
J Med Chem; 2010 May; 53(10):3954-63. PubMed ID: 20408530
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of a new series of 1,2,4-triazolo[1,5-a]-1,3,5-triazines as human A(2A) adenosine receptor antagonists with improved water solubility.
Federico S; Paoletta S; Cheong SL; Pastorin G; Cacciari B; Stragliotto S; Klotz KN; Siegel J; Gao ZG; Jacobson KA; Moro S; Spalluto G
J Med Chem; 2011 Feb; 54(3):877-89. PubMed ID: 21214204
[TBL] [Abstract][Full Text] [Related]
13. New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists.
Baraldi PG; Tabrizi MA; Preti D; Bovero A; Fruttarolo F; Romagnoli R; Zaid NA; Moorman AR; Varani K; Borea PA
J Med Chem; 2005 Jul; 48(15):5001-8. PubMed ID: 16033279
[TBL] [Abstract][Full Text] [Related]
14. Derivatives of 4-amino-6-hydroxy-2-mercaptopyrimidine as novel, potent, and selective A3 adenosine receptor antagonists.
Cosimelli B; Greco G; Ehlardo M; Novellino E; Da Settimo F; Taliani S; La Motta C; Bellandi M; Tuccinardi T; Martinelli A; Ciampi O; Trincavelli ML; Martini C
J Med Chem; 2008 Mar; 51(6):1764-70. PubMed ID: 18269230
[TBL] [Abstract][Full Text] [Related]
15. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
Pastorin G; Da Ros T; Spalluto G; Deflorian F; Moro S; Cacciari B; Baraldi PG; Gessi S; Varani K; Borea PA
J Med Chem; 2003 Sep; 46(20):4287-96. PubMed ID: 13678407
[TBL] [Abstract][Full Text] [Related]
16. 3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: a new class of selective A1 adenosine receptor antagonists.
Da Settimo F; Primofiore G; Taliani S; Marini AM; La Motta C; Novellino E; Greco G; Lavecchia A; Trincavelli L; Martini C
J Med Chem; 2001 Feb; 44(3):316-27. PubMed ID: 11462973
[TBL] [Abstract][Full Text] [Related]
17. Geometrically constrained analogues of N-benzylindolylglyoxylylamides: [1, 2, 4]triazino[4, 3-a]benzimidazol-4(10H)-one derivatives as potential new ligands at the benzodiazepine receptor.
Primofiore G; Da Settimo F; Taliani S; Marini AM; Simorini F; Novellino E; Greco G; Trincavelli L; Martini C
Arch Pharm (Weinheim); 2003 Sep; 336(9):413-21. PubMed ID: 14528489
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological activity of new potential agonists for the human adenosine A2A receptor.
Bosch MP; Campos F; Niubó I; Rosell G; Díaz JL; Brea J; Loza MI; Guerrero A
J Med Chem; 2004 Jul; 47(16):4041-53. PubMed ID: 15267242
[TBL] [Abstract][Full Text] [Related]
19. Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.
Kalla RV; Elzein E; Perry T; Li X; Palle V; Varkhedkar V; Gimbel A; Maa T; Zeng D; Zablocki J
J Med Chem; 2006 Jun; 49(12):3682-92. PubMed ID: 16759111
[TBL] [Abstract][Full Text] [Related]
20. 2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a new scaffold to obtain potent and selective human A3 adenosine receptor antagonists: new insights into the receptor-antagonist recognition.
Lenzi O; Colotta V; Catarzi D; Varano F; Poli D; Filacchioni G; Varani K; Vincenzi F; Borea PA; Paoletta S; Morizzo E; Moro S
J Med Chem; 2009 Dec; 52(23):7640-52. PubMed ID: 19743865
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
