BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

421 related articles for article (PubMed ID: 22261533)

  • 1. Hepatotoxicity associated with 6-methyl mercaptopurine formation during azathioprine and 6-mercaptopurine therapy does not occur on the short-term during 6-thioguanine therapy in IBD treatment.
    van Asseldonk DP; Seinen ML; de Boer NK; van Bodegraven AA; Mulder CJ
    J Crohns Colitis; 2012 Feb; 6(1):95-101. PubMed ID: 22261533
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine.
    Dubinsky MC; Feldman EJ; Abreu MT; Targan SR; Vasiliauskas EA
    Am J Gastroenterol; 2003 May; 98(5):1058-63. PubMed ID: 12809828
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease.
    Gearry RB; Barclay ML
    J Gastroenterol Hepatol; 2005 Aug; 20(8):1149-57. PubMed ID: 16048561
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thiopurine methyltransferase activity combined with 6-thioguanine metabolite levels predicts clinical response to thiopurines in patients with inflammatory bowel disease.
    Kwan LY; Devlin SM; Mirocha JM; Papadakis KA
    Dig Liver Dis; 2008 Jun; 40(6):425-32. PubMed ID: 18304898
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Routinely Established Skewed Thiopurine Metabolism Leads to a Strikingly High Rate of Early Therapeutic Failure in Patients With Inflammatory Bowel Disease.
    Kreijne JE; Seinen ML; Wilhelm AJ; Bouma G; Mulder CJ; van Bodegraven AA; de Boer NK
    Ther Drug Monit; 2015 Dec; 37(6):797-804. PubMed ID: 25853923
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thiopurine-induced liver injury in patients with inflammatory bowel disease: a systematic review.
    Gisbert JP; González-Lama Y; Maté J
    Am J Gastroenterol; 2007 Jul; 102(7):1518-27. PubMed ID: 17391318
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Why measure thiopurine methyltransferase activity? Direct administration of 6-thioguanine might be the alternative for 6-mercaptopurine or azathioprine.
    de Jong D; Mulder CJ; van Sorge AA
    Gut; 2001 Dec; 49(6):874. PubMed ID: 11758505
    [No Abstract]   [Full Text] [Related]  

  • 8. Hepatotoxicity of 6-mercaptopurine (6-MP) and Azathioprine (AZA) in adult IBD patients.
    Shaye OA; Yadegari M; Abreu MT; Poordad F; Simon K; Martin P; Papadakis KA; Ippoliti A; Vasiliauskas E; Tran TT
    Am J Gastroenterol; 2007 Nov; 102(11):2488-94. PubMed ID: 17764490
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 6-Thioguanine treatment in inflammatory bowel disease: a critical appraisal by a European 6-TG working party.
    de Boer NK; Reinisch W; Teml A; van Bodegraven AA; Schwab M; Lukas M; Ochsenkühn T; Petritsch W; Knoflach P; Almer S; van der Merwe SW; Herrlinger KR; Seiderer J; Vogelsang H; Mulder CJ;
    Digestion; 2006; 73(1):25-31. PubMed ID: 16493198
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Efficacy, safety and drug survival of thioguanine as maintenance treatment for inflammatory bowel disease: a retrospective multi-centre study in the United Kingdom.
    Bayoumy AB; van Liere ELSA; Simsek M; Warner B; Loganayagam A; Sanderson JD; Anderson S; Nolan J; de Boer NK; Mulder CJJ; Ansari A
    BMC Gastroenterol; 2020 Sep; 20(1):296. PubMed ID: 32917155
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intrauterine exposure and pharmacology of conventional thiopurine therapy in pregnant patients with inflammatory bowel disease.
    Jharap B; de Boer NK; Stokkers P; Hommes DW; Oldenburg B; Dijkstra G; van der Woude CJ; de Jong DJ; Mulder CJ; van Elburg RM; van Bodegraven AA;
    Gut; 2014 Mar; 63(3):451-7. PubMed ID: 23424097
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Review article: thiopurines in inflammatory bowel disease.
    Derijks LJ; Gilissen LP; Hooymans PM; Hommes DW
    Aliment Pharmacol Ther; 2006 Sep; 24(5):715-29. PubMed ID: 16918876
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Low-dose azathioprine or mercaptopurine in combination with allopurinol can bypass many adverse drug reactions in patients with inflammatory bowel disease.
    Ansari A; Patel N; Sanderson J; O'Donohue J; Duley JA; Florin TH
    Aliment Pharmacol Ther; 2010 Mar; 31(6):640-7. PubMed ID: 20015102
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Does lymphopenia or macrocytosis reflect 6-thioguanine levels in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine?
    Heerasing NM; Ng JF; Dowling D
    Intern Med J; 2016 Apr; 46(4):465-9. PubMed ID: 26425841
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thiopurine therapy in inflammatory bowel disease patients: analyses of two 8-year intercept cohorts.
    Jharap B; Seinen ML; de Boer NK; van Ginkel JR; Linskens RK; Kneppelhout JC; Mulder CJ; van Bodegraven AA
    Inflamm Bowel Dis; 2010 Sep; 16(9):1541-9. PubMed ID: 20155846
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 6-Thioguanine seems promising in azathioprine- or 6-mercaptopurine-intolerant inflammatory bowel disease patients: a short-term safety assessment.
    Derijks LJ; de Jong DJ; Gilissen LP; Engels LG; Hooymans PM; Jansen JB; Mulder CJ
    Eur J Gastroenterol Hepatol; 2003 Jan; 15(1):63-7. PubMed ID: 12544696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dosing 6-thioguanine in inflammatory bowel disease: expert-based guidelines for daily practice.
    Seinen ML; van Asseldonk DP; Mulder CJ; de Boer NK
    J Gastrointestin Liver Dis; 2010 Sep; 19(3):291-4. PubMed ID: 20922194
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficacy of thioguanine treatment in inflammatory bowel disease: A systematic review.
    Meijer B; Mulder CJ; Peters GJ; van Bodegraven AA; de Boer NK
    World J Gastroenterol; 2016 Oct; 22(40):9012-9021. PubMed ID: 27833392
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Is there a role for thioguanine therapy in IBD in 2017 and beyond?
    Taylor KM; Ward MG; Blaker PA; Sparrow MP
    Expert Rev Gastroenterol Hepatol; 2017 May; 11(5):473-486. PubMed ID: 28276819
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Optimizing Thiopurine Therapy in Inflammatory Bowel Disease Among 2 Real-life Intercept Cohorts: Effect of Allopurinol Comedication?
    Meijer B; Seinen ML; van Egmond R; Bouma G; Mulder CJJ; van Bodegraven AA; de Boer NKH
    Inflamm Bowel Dis; 2017 Nov; 23(11):2011-2017. PubMed ID: 28617756
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.