776 related articles for article (PubMed ID: 22265415)
21. Potentiated suppression of Dickkopf-1 in breast cancer by combined administration of the mevalonate pathway inhibitors zoledronic acid and statins.
Göbel A; Browne AJ; Thiele S; Rauner M; Hofbauer LC; Rachner TD
Breast Cancer Res Treat; 2015 Dec; 154(3):623-31. PubMed ID: 26515701
[TBL] [Abstract][Full Text] [Related]
22. Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44.
Mandal CC; Ghosh-Choudhury N; Yoneda T; Choudhury GG; Ghosh-Choudhury N
J Biol Chem; 2011 Apr; 286(13):11314-27. PubMed ID: 21199873
[TBL] [Abstract][Full Text] [Related]
23. Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence.
Wei S; Liu L; Chen Z; Yin W; Liu Y; Ouyang Q; Zeng F; Nie Y; Chen T
J Cell Mol Med; 2020 Jan; 24(1):276-284. PubMed ID: 31746143
[TBL] [Abstract][Full Text] [Related]
24. Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53.
Ghavami S; Mutawe MM; Sharma P; Yeganeh B; McNeill KD; Klonisch T; Unruh H; Kashani HH; Schaafsma D; Los M; Halayko AJ
PLoS One; 2011 Jan; 6(1):e16523. PubMed ID: 21304979
[TBL] [Abstract][Full Text] [Related]
25. Targeting mutant p53 through the mevalonate pathway.
Freed-Pastor W; Prives C
Nat Cell Biol; 2016 Oct; 18(11):1122-1124. PubMed ID: 27784901
[TBL] [Abstract][Full Text] [Related]
26. Anti-cancer efficacy of SREBP inhibitor, alone or in combination with docetaxel, in prostate cancer harboring p53 mutations.
Li X; Wu JB; Chung LW; Huang WC
Oncotarget; 2015 Dec; 6(38):41018-32. PubMed ID: 26512780
[TBL] [Abstract][Full Text] [Related]
27. Inhibition of human breast cancer cell growth by blockade of the mevalonate-protein prenylation pathway is not prevented by overexpression of cyclin D1.
Germano D; Pacilio C; Cancemi M; Cicatiello L; Altucci L; Petrizzi VB; Sperandio C; Salzano S; Michalides RJ; Taya Y; Bresciani F; Weisz A
Breast Cancer Res Treat; 2001 May; 67(1):23-33. PubMed ID: 11518463
[TBL] [Abstract][Full Text] [Related]
28. Cholesterol and beyond - The role of the mevalonate pathway in cancer biology.
Göbel A; Rauner M; Hofbauer LC; Rachner TD
Biochim Biophys Acta Rev Cancer; 2020 Apr; 1873(2):188351. PubMed ID: 32007596
[TBL] [Abstract][Full Text] [Related]
29. Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK.
Koyuturk M; Ersoz M; Altiok N
Cancer Lett; 2007 Jun; 250(2):220-8. PubMed ID: 17125918
[TBL] [Abstract][Full Text] [Related]
30. Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria.
Lee SK; Kim YS
Int J Oncol; 2013 Mar; 42(3):810-6. PubMed ID: 23354132
[TBL] [Abstract][Full Text] [Related]
31. MicroRNA-874 targets phosphomevalonate kinase and inhibits cancer cell growth via the mevalonate pathway.
Aersilan A; Hashimoto N; Yamagata K; Yokoyama M; Nakayama A; Shi X; Nagano H; Sakuma I; Nohata N; Kinoshita T; Seki N; Rahmutulla B; Kaneda A; Zhahara SN; Gong Y; Nishimura M; Kawauchi S; Kawakami E; Tanaka T
Sci Rep; 2022 Nov; 12(1):18443. PubMed ID: 36323841
[TBL] [Abstract][Full Text] [Related]
32. Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.
Pandyra AA; Mullen PJ; Goard CA; Ericson E; Sharma P; Kalkat M; Yu R; Pong JT; Brown KR; Hart T; Gebbia M; Lang KS; Giaever G; Nislow C; Moffat J; Penn LZ
Oncotarget; 2015 Sep; 6(29):26909-21. PubMed ID: 26353928
[TBL] [Abstract][Full Text] [Related]
33. Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
Kah J; Wüstenberg A; Keller AD; Sirma H; Montalbano R; Ocker M; Volz T; Dandri M; Tiegs G; Sass G
Oncol Rep; 2012 Sep; 28(3):1077-83. PubMed ID: 22710979
[TBL] [Abstract][Full Text] [Related]
34. Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis.
Chou CW; Lin CH; Hsiao TH; Lo CC; Hsieh CY; Huang CC; Sher YP
Sci Rep; 2019 Dec; 9(1):20403. PubMed ID: 31892709
[TBL] [Abstract][Full Text] [Related]
35. Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins.
Ghavami S; Sharma P; Yeganeh B; Ojo OO; Jha A; Mutawe MM; Kashani HH; Los MJ; Klonisch T; Unruh H; Halayko AJ
Biochim Biophys Acta; 2014 Jul; 1843(7):1259-71. PubMed ID: 24637330
[TBL] [Abstract][Full Text] [Related]
36. Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention.
Mo H; Elson CE
Exp Biol Med (Maywood); 2004 Jul; 229(7):567-85. PubMed ID: 15229351
[TBL] [Abstract][Full Text] [Related]
37. Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway.
Gopalan A; Yu W; Sanders BG; Kline K
Cancer Lett; 2013 Feb; 329(1):9-16. PubMed ID: 22960596
[TBL] [Abstract][Full Text] [Related]
38. Statins, Mevalonate Pathway and its Intermediate Products in Placental Development and Preeclampsia.
Ermini L; Post M; Caniggia I
Curr Mol Pharmacol; 2017; 10(2):152-160. PubMed ID: 26758951
[TBL] [Abstract][Full Text] [Related]
39. Could drugs inhibiting the mevalonate pathway also target cancer stem cells?
Likus W; Siemianowicz K; Bieńk K; Pakuła M; Pathak H; Dutta C; Wang Q; Shojaei S; Assaraf YG; Ghavami S; Cieślar-Pobuda A; Łos MJ
Drug Resist Updat; 2016 Mar; 25():13-25. PubMed ID: 27155373
[TBL] [Abstract][Full Text] [Related]
40. Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.
Neilsen PM; Noll JE; Mattiske S; Bracken CP; Gregory PA; Schulz RB; Lim SP; Kumar R; Suetani RJ; Goodall GJ; Callen DF
Oncogene; 2013 Jun; 32(24):2992-3000. PubMed ID: 22797073
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
