BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

806 related articles for article (PubMed ID: 22265415)

  • 41. Combined inhibition of the mevalonate pathway with statins and zoledronic acid potentiates their anti-tumor effects in human breast cancer cells.
    Göbel A; Thiele S; Browne AJ; Rauner M; Zinna VM; Hofbauer LC; Rachner TD
    Cancer Lett; 2016 May; 375(1):162-171. PubMed ID: 26968247
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate.
    Straka MS; Panini SR
    Arch Biochem Biophys; 1995 Feb; 317(1):235-43. PubMed ID: 7872789
    [TBL] [Abstract][Full Text] [Related]  

  • 43. 3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation.
    Blanco-Colio LM; Villa A; Ortego M; Hernández-Presa MA; Pascual A; Plaza JJ; Egido J
    Atherosclerosis; 2002 Mar; 161(1):17-26. PubMed ID: 11882313
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Mutant p53 Amplifies Epidermal Growth Factor Receptor Family Signaling to Promote Mammary Tumorigenesis.
    Yallowitz AR; Li D; Lobko A; Mott D; Nemajerova A; Marchenko N
    Mol Cancer Res; 2015 Apr; 13(4):743-54. PubMed ID: 25573952
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy.
    Miettinen TP; Björklund M
    Cell Rep; 2015 Dec; 13(11):2610-2620. PubMed ID: 26686643
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis.
    Lee SK; Kim YC; Song SB; Kim YS
    Biochem Biophys Res Commun; 2010 Jan; 391(4):1592-7. PubMed ID: 20043868
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia.
    Bi X; Baudry M; Liu J; Yao Y; Fu L; Brucher F; Lynch G
    J Biol Chem; 2004 Nov; 279(46):48238-45. PubMed ID: 15364922
    [TBL] [Abstract][Full Text] [Related]  

  • 48. DHX33 mediates p53 to regulate mevalonate pathway gene transcription in human cancers.
    Nie G; Chen S; Song Q; Zou D; Li M; Tang X; Deng Y; Huang B; Yang M; Lv G; Zhang Y
    Biochim Biophys Acta Gen Subj; 2024 Mar; 1868(3):130547. PubMed ID: 38143011
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: a role for sterol regulatory element-binding protein-2.
    Deakin S; Leviev I; Guernier S; James RW
    Arterioscler Thromb Vasc Biol; 2003 Nov; 23(11):2083-9. PubMed ID: 14500290
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Beyond the Mevalonate Pathway: Control of Post-Prenylation Processing by Mutant p53.
    Borini Etichetti CM; Arel Zalazar E; Cocordano N; Girardini J
    Front Oncol; 2020; 10():595034. PubMed ID: 33224889
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia.
    Dubuc G; Chamberland A; Wassef H; Davignon J; Seidah NG; Bernier L; Prat A
    Arterioscler Thromb Vasc Biol; 2004 Aug; 24(8):1454-9. PubMed ID: 15178557
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Statin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis.
    Tanaka K; Osada H; Murakami-Tonami Y; Horio Y; Hida T; Sekido Y
    Cancer Lett; 2017 Jan; 385():215-224. PubMed ID: 27773750
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Isoforms of RNF128 Regulate the Stability of Mutant P53 in Barrett's Esophageal Cells.
    Ray D; Ray P; Ferrer-Torres D; Wang Z; Nancarrow D; Yoon HW; San Martinho M; Hinton T; Owens S; Thomas D; Jiang H; Lawrence TS; Lin J; Lagisetty K; Chang AC; Beer DG
    Gastroenterology; 2020 Feb; 158(3):583-597.e1. PubMed ID: 31715145
    [TBL] [Abstract][Full Text] [Related]  

  • 54. p140Cap modulates the mevalonate pathway decreasing cell migration and enhancing drug sensitivity in breast cancer cells.
    Centonze G; Natalini D; Grasso S; Morellato A; Salemme V; Piccolantonio A; D'Attanasio G; Savino A; Bianciotto OT; Fragomeni M; Scavuzzo A; Poncina M; Nigrelli F; De Gregorio M; Poli V; Arina P; Taverna D; Kopecka J; Dupont S; Turco E; Riganti C; Defilippi P
    Cell Death Dis; 2023 Dec; 14(12):849. PubMed ID: 38123597
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells.
    Karlic H; Thaler R; Gerner C; Grunt T; Proestling K; Haider F; Varga F
    Cancer Genet; 2015 May; 208(5):241-52. PubMed ID: 25978957
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
    Maeda T; Horiuchi N
    J Biochem; 2009 Jun; 145(6):771-81. PubMed ID: 19254925
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion.
    Mehta SA; Christopherson KW; Bhat-Nakshatri P; Goulet RJ; Broxmeyer HE; Kopelovich L; Nakshatri H
    Oncogene; 2007 May; 26(23):3329-37. PubMed ID: 17130833
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells.
    Junk DJ; Vrba L; Watts GS; Oshiro MM; Martinez JD; Futscher BW
    Neoplasia; 2008 May; 10(5):450-61. PubMed ID: 18472962
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Different statins produce highly divergent changes in gene expression profiles of human hepatoma cells: a pilot study.
    Leszczynska A; Gora M; Plochocka D; Hoser G; Szkopinska A; Koblowska M; Iwanicka-Nowicka R; Kotlinski M; Rawa K; Kiliszek M; Burzynska B
    Acta Biochim Pol; 2011; 58(4):635-9. PubMed ID: 22132374
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Statins impair survival of primary human mesenchymal progenitor cells via mevalonate depletion, NF-κB signaling, and Bnip3.
    Li Y; Müller AL; Ngo MA; Sran K; Bellan D; Arora RC; Kirshenbaum LA; Freed DH
    J Cardiovasc Transl Res; 2015 Mar; 8(2):96-105. PubMed ID: 25547946
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 41.