BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

400 related articles for article (PubMed ID: 22266907)

  • 1. Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability.
    Kumareswaran R; Ludkovski O; Meng A; Sykes J; Pintilie M; Bristow RG
    J Cell Sci; 2012 Jan; 125(Pt 1):189-99. PubMed ID: 22266907
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling.
    Yamauchi M; Oka Y; Yamamoto M; Niimura K; Uchida M; Kodama S; Watanabe M; Sekine I; Yamashita S; Suzuki K
    DNA Repair (Amst); 2008 Mar; 7(3):405-17. PubMed ID: 18248856
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relationship between DNA double-strand break rejoining and cell survival after exposure to ionizing radiation in human fibroblast strains with differing ATM/p53 status: implications for evaluation of clinical radiosensitivity.
    Mirzayans R; Severin D; Murray D
    Int J Radiat Oncol Biol Phys; 2006 Dec; 66(5):1498-505. PubMed ID: 17126209
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.
    An J; Huang YC; Xu QZ; Zhou LJ; Shang ZF; Huang B; Wang Y; Liu XD; Wu DC; Zhou PK
    BMC Mol Biol; 2010 Mar; 11():18. PubMed ID: 20205745
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.
    Goodarzi AA; Jeggo P; Lobrich M
    DNA Repair (Amst); 2010 Dec; 9(12):1273-82. PubMed ID: 21036673
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells.
    Toller IM; Neelsen KJ; Steger M; Hartung ML; Hottiger MO; Stucki M; Kalali B; Gerhard M; Sartori AA; Lopes M; Müller A
    Proc Natl Acad Sci U S A; 2011 Sep; 108(36):14944-9. PubMed ID: 21896770
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX.
    Ha L; Ceryak S; Patierno SR
    Carcinogenesis; 2004 Nov; 25(11):2265-74. PubMed ID: 15284180
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells.
    Harding SM; Coackley C; Bristow RG
    Radiother Oncol; 2011 Jun; 99(3):307-12. PubMed ID: 21680038
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.
    Moon SH; Lin L; Zhang X; Nguyen TA; Darlington Y; Waldman AS; Lu X; Donehower LA
    J Biol Chem; 2010 Apr; 285(17):12935-47. PubMed ID: 20118229
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SNM1A acts downstream of ATM to promote the G1 cell cycle checkpoint.
    Akhter S; Legerski RJ
    Biochem Biophys Res Commun; 2008 Dec; 377(1):236-41. PubMed ID: 18848520
    [TBL] [Abstract][Full Text] [Related]  

  • 11. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.
    Helmink BA; Tubbs AT; Dorsett Y; Bednarski JJ; Walker LM; Feng Z; Sharma GG; McKinnon PJ; Zhang J; Bassing CH; Sleckman BP
    Nature; 2011 Jan; 469(7329):245-9. PubMed ID: 21160476
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.
    Noon AT; Shibata A; Rief N; Löbrich M; Stewart GS; Jeggo PA; Goodarzi AA
    Nat Cell Biol; 2010 Feb; 12(2):177-84. PubMed ID: 20081839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA-PK.
    Meyer B; Voss KO; Tobias F; Jakob B; Durante M; Taucher-Scholz G
    Nucleic Acids Res; 2013 Jul; 41(12):6109-18. PubMed ID: 23620287
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.
    Sordet O; Redon CE; Guirouilh-Barbat J; Smith S; Solier S; Douarre C; Conti C; Nakamura AJ; Das BB; Nicolas E; Kohn KW; Bonner WM; Pommier Y
    EMBO Rep; 2009 Aug; 10(8):887-93. PubMed ID: 19557000
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.
    Riballo E; Kühne M; Rief N; Doherty A; Smith GC; Recio MJ; Reis C; Dahm K; Fricke A; Krempler A; Parker AR; Jackson SP; Gennery A; Jeggo PA; Löbrich M
    Mol Cell; 2004 Dec; 16(5):715-24. PubMed ID: 15574327
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks in vivo.
    Al Rashid ST; Dellaire G; Cuddihy A; Jalali F; Vaid M; Coackley C; Folkard M; Xu Y; Chen BP; Chen DJ; Lilge L; Prise KM; Bazett Jones DP; Bristow RG
    Cancer Res; 2005 Dec; 65(23):10810-21. PubMed ID: 16322227
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [gamma H2AX in the recognition of DNA double-strand breaks].
    Podhorecka M
    Postepy Hig Med Dosw (Online); 2009 Feb; 63():92-8. PubMed ID: 19252467
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks.
    Ismail IH; Nyström S; Nygren J; Hammarsten O
    J Biol Chem; 2005 Feb; 280(6):4649-55. PubMed ID: 15546858
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke.
    Tanaka T; Huang X; Jorgensen E; Gietl D; Traganos F; Darzynkiewicz Z; Albino AP
    BMC Cell Biol; 2007 Jun; 8():26. PubMed ID: 17594478
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis.
    Kurose A; Tanaka T; Huang X; Traganos F; Dai W; Darzynkiewicz Z
    Cytometry A; 2006 Apr; 69(4):212-21. PubMed ID: 16528719
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.