These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

718 related articles for article (PubMed ID: 22267580)

  • 1. Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR.
    Liu JJ; Horst R; Katritch V; Stevens RC; Wüthrich K
    Science; 2012 Mar; 335(6072):1106-10. PubMed ID: 22267580
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Simulations of biased agonists in the β(2) adrenergic receptor with accelerated molecular dynamics.
    Tikhonova IG; Selvam B; Ivetac A; Wereszczynski J; McCammon JA
    Biochemistry; 2013 Aug; 52(33):5593-603. PubMed ID: 23879802
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biased Signaling of the G-Protein-Coupled Receptor β
    Lamichhane R; Liu JJ; White KL; Katritch V; Stevens RC; Wüthrich K; Millar DP
    Structure; 2020 Mar; 28(3):371-377.e3. PubMed ID: 31978323
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes.
    Katritch V; Reynolds KA; Cherezov V; Hanson MA; Roth CB; Yeager M; Abagyan R
    J Mol Recognit; 2009; 22(4):307-18. PubMed ID: 19353579
    [TBL] [Abstract][Full Text] [Related]  

  • 5. β
    Eddy MT; Didenko T; Stevens RC; Wüthrich K
    Structure; 2016 Dec; 24(12):2190-2197. PubMed ID: 27839952
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The β-blocker Nebivolol Is a GRK/β-arrestin biased agonist.
    Erickson CE; Gul R; Blessing CP; Nguyen J; Liu T; Pulakat L; Bastepe M; Jackson EK; Andresen BT
    PLoS One; 2013; 8(8):e71980. PubMed ID: 23977191
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the β2-adrenergic receptor.
    Goetz A; Lanig H; Gmeiner P; Clark T
    J Mol Biol; 2011 Dec; 414(4):611-23. PubMed ID: 22037586
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.
    Staus DP; Strachan RT; Manglik A; Pani B; Kahsai AW; Kim TH; Wingler LM; Ahn S; Chatterjee A; Masoudi A; Kruse AC; Pardon E; Steyaert J; Weis WI; Prosser RS; Kobilka BK; Costa T; Lefkowitz RJ
    Nature; 2016 Jul; 535(7612):448-52. PubMed ID: 27409812
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling.
    Wisler JW; DeWire SM; Whalen EJ; Violin JD; Drake MT; Ahn S; Shenoy SK; Lefkowitz RJ
    Proc Natl Acad Sci U S A; 2007 Oct; 104(42):16657-62. PubMed ID: 17925438
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.
    Rasmussen SG; Choi HJ; Fung JJ; Pardon E; Casarosa P; Chae PS; Devree BT; Rosenbaum DM; Thian FS; Kobilka TS; Schnapp A; Konetzki I; Sunahara RK; Gellman SH; Pautsch A; Steyaert J; Weis WI; Kobilka BK
    Nature; 2011 Jan; 469(7329):175-80. PubMed ID: 21228869
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands.
    Littmann T; Göttle M; Reinartz MT; Kälble S; Wainer IW; Ozawa T; Seifert R
    J Pharmacol Exp Ther; 2015 Nov; 355(2):183-90. PubMed ID: 26306764
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling.
    Manglik A; Kim TH; Masureel M; Altenbach C; Yang Z; Hilger D; Lerch MT; Kobilka TS; Thian FS; Hubbell WL; Prosser RS; Kobilka BK
    Cell; 2015 May; 161(5):1101-1111. PubMed ID: 25981665
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1.
    Smith KJ; Baillie GS; Hyde EI; Li X; Houslay TM; McCahill A; Dunlop AJ; Bolger GB; Klussmann E; Adams DR; Houslay MD
    Cell Signal; 2007 Dec; 19(12):2612-24. PubMed ID: 17900862
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural features of β2 adrenergic receptor: crystal structures and beyond.
    Bang I; Choi HJ
    Mol Cells; 2015; 38(2):105-11. PubMed ID: 25537861
    [TBL] [Abstract][Full Text] [Related]  

  • 15. beta-arrestin-biased agonism at the beta2-adrenergic receptor.
    Drake MT; Violin JD; Whalen EJ; Wisler JW; Shenoy SK; Lefkowitz RJ
    J Biol Chem; 2008 Feb; 283(9):5669-76. PubMed ID: 18086673
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure and conformational changes in the C-terminal domain of the beta2-adrenoceptor: insights from fluorescence resonance energy transfer studies.
    Granier S; Kim S; Shafer AM; Ratnala VR; Fung JJ; Zare RN; Kobilka B
    J Biol Chem; 2007 May; 282(18):13895-905. PubMed ID: 17347144
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure and function of an irreversible agonist-β(2) adrenoceptor complex.
    Rosenbaum DM; Zhang C; Lyons JA; Holl R; Aragao D; Arlow DH; Rasmussen SG; Choi HJ; Devree BT; Sunahara RK; Chae PS; Gellman SH; Dror RO; Shaw DE; Weis WI; Caffrey M; Gmeiner P; Kobilka BK
    Nature; 2011 Jan; 469(7329):236-40. PubMed ID: 21228876
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carvedilol binding to β2-adrenergic receptors inhibits CFTR-dependent anion secretion in airway epithelial cells.
    Peitzman ER; Zaidman NA; Maniak PJ; O'Grady SM
    Am J Physiol Lung Cell Mol Physiol; 2016 Jan; 310(1):L50-8. PubMed ID: 26566905
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.
    Kim IM; Tilley DG; Chen J; Salazar NC; Whalen EJ; Violin JD; Rockman HA
    Proc Natl Acad Sci U S A; 2008 Sep; 105(38):14555-60. PubMed ID: 18787115
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insight into partial agonism by observing multiple equilibria for ligand-bound and G
    Solt AS; Bostock MJ; Shrestha B; Kumar P; Warne T; Tate CG; Nietlispach D
    Nat Commun; 2017 Nov; 8(1):1795. PubMed ID: 29176642
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.