222 related articles for article (PubMed ID: 22267724)
1. Activation of sterol-response element-binding proteins (SREBP) in alveolar type II cells enhances lipogenesis causing pulmonary lipotoxicity.
Plantier L; Besnard V; Xu Y; Ikegami M; Wert SE; Hunt AN; Postle AD; Whitsett JA
J Biol Chem; 2012 Mar; 287(13):10099-10114. PubMed ID: 22267724
[TBL] [Abstract][Full Text] [Related]
2. Epithelial SCAP/INSIG/SREBP signaling regulates multiple biological processes during perinatal lung maturation.
Bridges JP; Schehr A; Wang Y; Huo L; Besnard V; Ikegami M; Whitsett JA; Xu Y
PLoS One; 2014; 9(5):e91376. PubMed ID: 24806461
[TBL] [Abstract][Full Text] [Related]
3. Deletion of Scap in alveolar type II cells influences lung lipid homeostasis and identifies a compensatory role for pulmonary lipofibroblasts.
Besnard V; Wert SE; Stahlman MT; Postle AD; Xu Y; Ikegami M; Whitsett JA
J Biol Chem; 2009 Feb; 284(6):4018-30. PubMed ID: 19074148
[TBL] [Abstract][Full Text] [Related]
4. The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.
Xu D; Wang Z; Xia Y; Shao F; Xia W; Wei Y; Li X; Qian X; Lee JH; Du L; Zheng Y; Lv G; Leu JS; Wang H; Xing D; Liang T; Hung MC; Lu Z
Nature; 2020 Apr; 580(7804):530-535. PubMed ID: 32322062
[TBL] [Abstract][Full Text] [Related]
5. Hypomorphic ASGR1 modulates lipid homeostasis via INSIG1-mediated SREBP signaling suppression.
Xu Y; Tao J; Yu X; Wu Y; Chen Y; You K; Zhang J; Getachew A; Pan T; Zhuang Y; Yuan F; Yang F; Lin X; Li YX
JCI Insight; 2021 Oct; 6(19):. PubMed ID: 34622799
[TBL] [Abstract][Full Text] [Related]
6. Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum.
Esquejo RM; Roqueta-Rivera M; Shao W; Phelan PE; Seneviratne U; Am Ende CW; Hershberger PM; Machamer CE; Espenshade PJ; Osborne TF
Cell Chem Biol; 2021 Feb; 28(2):169-179.e7. PubMed ID: 33096051
[TBL] [Abstract][Full Text] [Related]
7. Insulin-induced gene 1 and 2 isoforms synergistically regulate triacylglycerol accumulation, lipid droplet formation, and lipogenic gene expression in goat mammary epithelial cells.
Li C; Wang M; Zhang T; He Q; Shi H; Luo J; Loor JJ
J Dairy Sci; 2019 Feb; 102(2):1736-1746. PubMed ID: 30594361
[TBL] [Abstract][Full Text] [Related]
8. Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.
Engelking LJ; Liang G; Hammer RE; Takaishi K; Kuriyama H; Evers BM; Li WP; Horton JD; Goldstein JL; Brown MS
J Clin Invest; 2005 Sep; 115(9):2489-98. PubMed ID: 16100574
[TBL] [Abstract][Full Text] [Related]
9. Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression.
Azzu V; Vacca M; Kamzolas I; Hall Z; Leslie J; Carobbio S; Virtue S; Davies SE; Lukasik A; Dale M; Bohlooly-Y M; Acharjee A; Lindén D; Bidault G; Petsalaki E; Griffin JL; Oakley F; Allison MED; Vidal-Puig A
Mol Metab; 2021 Jun; 48():101210. PubMed ID: 33722690
[TBL] [Abstract][Full Text] [Related]
10. SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1.
Crewe C; Zhu Y; Paschoal VA; Joffin N; Ghaben AL; Gordillo R; Oh DY; Liang G; Horton JD; Scherer PE
JCI Insight; 2019 Jul; 5(15):. PubMed ID: 31310592
[TBL] [Abstract][Full Text] [Related]
11. COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions.
Takashima K; Saitoh A; Funabashi T; Hirose S; Yagi C; Nozaki S; Sato R; Shin HW; Nakayama K
J Cell Sci; 2015 Aug; 128(15):2805-15. PubMed ID: 26092941
[TBL] [Abstract][Full Text] [Related]
12. Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?
Le Hellard S; Theisen FM; Haberhausen M; Raeder MB; Fernø J; Gebhardt S; Hinney A; Remschmidt H; Krieg JC; Mehler-Wex C; Nöthen MM; Hebebrand J; Steen VM
Mol Psychiatry; 2009 Mar; 14(3):308-17. PubMed ID: 18195716
[TBL] [Abstract][Full Text] [Related]
13. Glutamine stimulates the gene expression and processing of sterol regulatory element binding proteins, thereby increasing the expression of their target genes.
Inoue J; Ito Y; Shimada S; Satoh SI; Sasaki T; Hashidume T; Kamoshida Y; Shimizu M; Sato R
FEBS J; 2011 Aug; 278(15):2739-50. PubMed ID: 21696544
[TBL] [Abstract][Full Text] [Related]
14. PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus.
Xu D; Wang Z; Zhang Y; Jiang W; Pan Y; Song BL; Chen Y
Nat Commun; 2015 Aug; 6():8100. PubMed ID: 26311497
[TBL] [Abstract][Full Text] [Related]
15. Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition.
Nakagawa Y; Wang Y; Han SI; Okuda K; Oishi A; Yagishita Y; Kumagai K; Ohno H; Osaki Y; Mizunoe Y; Araki M; Murayama Y; Iwasaki H; Konishi M; Itoh N; Matsuzaka T; Sone H; Yamada N; Shimano H
Cell Mol Gastroenterol Hepatol; 2021; 11(4):949-971. PubMed ID: 33246135
[TBL] [Abstract][Full Text] [Related]
16. miR-122 Regulates LHR Expression in Rat Granulosa Cells by Targeting Insig1 mRNA.
Menon B; Guo X; Garcia N; Gulappa T; Menon KMJ
Endocrinology; 2018 May; 159(5):2075-2082. PubMed ID: 29579170
[TBL] [Abstract][Full Text] [Related]
17. Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism.
Shimano H
Vitam Horm; 2002; 65():167-94. PubMed ID: 12481547
[TBL] [Abstract][Full Text] [Related]
18. Keratinocyte growth factor induces lipogenesis in alveolar type II cells through a sterol regulatory element binding protein-1c-dependent pathway.
Chang Y; Edeen K; Lu X; De Leon M; Mason RJ
Am J Respir Cell Mol Biol; 2006 Aug; 35(2):268-74. PubMed ID: 16601238
[TBL] [Abstract][Full Text] [Related]
19. Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells.
Xu Y; Ikegami M; Wang Y; Matsuzaki Y; Whitsett JA
BMC Genomics; 2007 Dec; 8():455. PubMed ID: 18070348
[TBL] [Abstract][Full Text] [Related]
20. Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals.
Hawkins JL; Robbins MD; Warren LC; Xia D; Petras SF; Valentine JJ; Varghese AH; Wang IK; Subashi TA; Shelly LD; Hay BA; Landschulz KT; Geoghegan KF; Harwood HJ
J Pharmacol Exp Ther; 2008 Sep; 326(3):801-8. PubMed ID: 18577702
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
