229 related articles for article (PubMed ID: 22271751)
1. Improving the diastereoselectivity of penicillin G acylase for ampicillin synthesis from racemic substrates.
Deaguero AL; Blum JK; Bommarius AS
Protein Eng Des Sel; 2012 Mar; 25(3):135-44. PubMed ID: 22271751
[TBL] [Abstract][Full Text] [Related]
2. Saturation mutagenesis reveals the importance of residues alphaR145 and alphaF146 of penicillin acylase in the synthesis of beta-lactam antibiotics.
Jager SA; Shapovalova IV; Jekel PA; Alkema WB; Svedas VK; Janssen DB
J Biotechnol; 2008 Jan; 133(1):18-26. PubMed ID: 17933411
[TBL] [Abstract][Full Text] [Related]
3. Crystal structure of penicillin G acylase from the Bro1 mutant strain of Providencia rettgeri.
McDonough MA; Klei HE; Kelly JA
Protein Sci; 1999 Oct; 8(10):1971-81. PubMed ID: 10548042
[TBL] [Abstract][Full Text] [Related]
4. Increasing the synthetic performance of penicillin acylase PAS2 by structure-inspired semi-random mutagenesis.
Gabor EM; Janssen DB
Protein Eng Des Sel; 2004 Jul; 17(7):571-9. PubMed ID: 15333773
[TBL] [Abstract][Full Text] [Related]
5. Efficient enzymatic synthesis of ampicillin by mutant Alcaligenes faecalis penicillin G acylase.
Deng S; Su E; Ma X; Yang S; Wei D
J Biotechnol; 2015 Apr; 199():62-8. PubMed ID: 25681630
[TBL] [Abstract][Full Text] [Related]
6. Role of alphaArg145 and betaArg263 in the active site of penicillin acylase of Escherichia coli.
Alkema WB; Prins AK; de Vries E; Janssen DB
Biochem J; 2002 Jul; 365(Pt 1):303-9. PubMed ID: 12071857
[TBL] [Abstract][Full Text] [Related]
7. Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism.
McVey CE; Walsh MA; Dodson GG; Wilson KS; Brannigan JA
J Mol Biol; 2001 Oct; 313(1):139-50. PubMed ID: 11601852
[TBL] [Abstract][Full Text] [Related]
8. Assessment of immobilized PGA orientation via the LC-MS analysis of tryptic digests of the wild type and its 3K-PGA mutant assists in the rational design of a high-performance biocatalyst.
Serra I; Ubiali D; Cecchini DA; Calleri E; Albertini AM; Terreni M; Temporini C
Anal Bioanal Chem; 2013 Jan; 405(2-3):745-53. PubMed ID: 22706479
[TBL] [Abstract][Full Text] [Related]
9. Efficient biocatalyst for large-scale synthesis of cephalosporins, obtained by combining immobilization and site-directed mutagenesis of penicillin acylase.
Cecchini DA; Pavesi R; Sanna S; Daly S; Xaiz R; Pregnolato M; Terreni M
Appl Microbiol Biotechnol; 2012 Sep; 95(6):1491-500. PubMed ID: 22228258
[TBL] [Abstract][Full Text] [Related]
10. Improved activity and pH stability of E. coli ATCC 11105 penicillin acylase by error-prone PCR.
Balci H; Ozturk MT; Pijning T; Ozturk SI; Gumusel F
Appl Microbiol Biotechnol; 2014 May; 98(10):4467-77. PubMed ID: 24389703
[TBL] [Abstract][Full Text] [Related]
11. Modifying the substrate specificity of penicillin G acylase to cephalosporin acylase by mutating active-site residues.
Oh B; Kim K; Park J; Yoon J; Han D; Kim Y
Biochem Biophys Res Commun; 2004 Jun; 319(2):486-92. PubMed ID: 15178432
[TBL] [Abstract][Full Text] [Related]
12. Penicillin acylase-catalyzed ampicillin synthesis using a pH gradient: a new approach to optimization.
Youshko MI; van Langen LM; de Vroom E; van Rantwijk F; Sheldon RA; Svedas VK
Biotechnol Bioeng; 2002 Jun; 78(5):589-93. PubMed ID: 12115129
[TBL] [Abstract][Full Text] [Related]
13. Efficient cascade synthesis of ampicillin from penicillin G potassium salt using wild and mutant penicillin G acylase from Alcaligenes faecalis.
Deng S; Ma X; Su E; Wei D
J Biotechnol; 2016 Feb; 219():142-8. PubMed ID: 26732414
[TBL] [Abstract][Full Text] [Related]
14. The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase.
Alkema WB; Dijkhuis AJ; De Vries E; Janssen DB
Eur J Biochem; 2002 Apr; 269(8):2093-100. PubMed ID: 11985586
[TBL] [Abstract][Full Text] [Related]
15. New active site oriented glyoxyl-agarose derivatives of Escherichia coli penicillin G acylase.
Cecchini DA; Serra I; Ubiali D; Terreni M; Albertini AM
BMC Biotechnol; 2007 Sep; 7():54. PubMed ID: 17845725
[TBL] [Abstract][Full Text] [Related]
16. Mutational analysis of a key residue in the substrate specificity of a cephalosporin acylase.
Otten LG; Sio CF; van der Sloot AM; Cool RH; Quax WJ
Chembiochem; 2004 Jun; 5(6):820-5. PubMed ID: 15174165
[TBL] [Abstract][Full Text] [Related]
17. [Penicillin G acylase--synthesis, regulation, production].
Grafková J; Sobotková L
Ceska Slov Farm; 2002 Jan; 51(1):6-10. PubMed ID: 11910744
[TBL] [Abstract][Full Text] [Related]
18. Evolutionary potential of (beta/alpha)8-barrels: in vitro enhancement of a "new" reaction in the enolase superfamily.
Vick JE; Schmidt DM; Gerlt JA
Biochemistry; 2005 Sep; 44(35):11722-9. PubMed ID: 16128573
[TBL] [Abstract][Full Text] [Related]
19. [Study of E. coli penicillin amidase. The pH dependence of the equilibrium constant of ampicillin enzymatic hydrolysis].
Margolin AL; Shviadas VIu; Nys PS; Kol'tsova EV; Savitskaia EM
Antibiotiki; 1978 Feb; 23(2):114-8. PubMed ID: 24408
[TBL] [Abstract][Full Text] [Related]
20. Improving the specific synthetic activity of a penicillin g acylase using DNA family shuffling.
Zhou Z; Zhang AH; Wang JR; Chen ML; Li RB; Yang S; Yuan ZY
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai); 2003 Jun; 35(6):573-9. PubMed ID: 12796820
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
