These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

95 related articles for article (PubMed ID: 22275121)

  • 1. Clarification of the pleiotropic effects of statins on mevalonate pathway and the feedback regulation of isoprenoids requires more comprehensive investigation.
    Bianco AM; Zanin V; Marcuzzi A; Crovella S
    Cell Biochem Funct; 2012 Mar; 30(2):176. PubMed ID: 22275121
    [No Abstract]   [Full Text] [Related]  

  • 2. Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell line.
    Polo MP; Crespo R; de Bravo MG
    Cell Biochem Funct; 2011 Aug; 29(6):452-8. PubMed ID: 21735455
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The balance between induction and inhibition of mevalonate pathway regulates cancer suppression by statins: A review of molecular mechanisms.
    Ahmadi Y; Ghorbanihaghjo A; Argani H
    Chem Biol Interact; 2017 Aug; 273():273-285. PubMed ID: 28668359
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK.
    Relja B; Meder F; Wang M; Blaheta R; Henrich D; Marzi I; Lehnert M
    Int J Oncol; 2011 Mar; 38(3):879-85. PubMed ID: 21206971
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Simvastatin induces growth inhibition and apoptosis in HepG2 and Huh7 hepatocellular carcinoma cells via upregulation of Notch1 expression.
    Huang X; Ma J; Xu J; Su Q; Zhao J
    Mol Med Rep; 2015 Mar; 11(3):2334-40. PubMed ID: 25412322
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impact of statins on modulation by insulin of expression of plasminogen activator inhibitor type-1.
    Sato Y; Dong J; Imagawa S; Ishimori N; Furumoto T; Tsutsui H; Sobel BE; Fujii S
    Coron Artery Dis; 2008 Aug; 19(5):355-61. PubMed ID: 18607173
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mevalonate-suppressive dietary isoprenoids for bone health.
    Mo H; Yeganehjoo H; Shah A; Mo WK; Soelaiman IN; Shen CL
    J Nutr Biochem; 2012 Dec; 23(12):1543-51. PubMed ID: 22981371
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors.
    Kubota T; Fujisaki K; Itoh Y; Yano T; Sendo T; Oishi R
    Biochem Pharmacol; 2004 Jun; 67(12):2175-86. PubMed ID: 15163549
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases.
    Ghittoni R; Patrussi L; Pirozzi K; Pellegrini M; Lazzerini PE; Capecchi PL; Pasini FL; Baldari CT
    FASEB J; 2005 Apr; 19(6):605-7. PubMed ID: 15677697
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Simvastatin elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and mevalonate-rho kinase pathways.
    Nagaoka T; Hein TW; Yoshida A; Kuo L
    Invest Ophthalmol Vis Sci; 2007 Feb; 48(2):825-32. PubMed ID: 17251484
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
    Kah J; Wüstenberg A; Keller AD; Sirma H; Montalbano R; Ocker M; Volz T; Dandri M; Tiegs G; Sass G
    Oncol Rep; 2012 Sep; 28(3):1077-83. PubMed ID: 22710979
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.
    Lee MH; Cho YS; Han YM
    Stem Cells; 2007 Jul; 25(7):1654-63. PubMed ID: 17464088
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Simvastatin promotes neurite outgrowth in the presence of inhibitory molecules found in central nervous system injury.
    Holmberg E; Nordstrom T; Gross M; Kluge B; Zhang SX; Doolen S
    J Neurotrauma; 2006 Sep; 23(9):1366-78. PubMed ID: 16958588
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HMG-CoA reductase inhibitor simvastatin mitigates VEGF-induced "inside-out" signaling to extracellular matrix by preventing RhoA activation.
    Xu H; Zeng L; Peng H; Chen S; Jones J; Chew TL; Sadeghi MM; Kanwar YS; Danesh FR
    Am J Physiol Renal Physiol; 2006 Nov; 291(5):F995-1004. PubMed ID: 16774905
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HMG-CoA reductase inhibitors induce apoptosis in pericytes.
    Boucher K; Siegel CS; Sharma P; Hauschka PV; Solomon KR
    Microvasc Res; 2006 Mar; 71(2):91-102. PubMed ID: 16427097
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy.
    Danesh FR; Sadeghi MM; Amro N; Philips C; Zeng L; Lin S; Sahai A; Kanwar YS
    Proc Natl Acad Sci U S A; 2002 Jun; 99(12):8301-5. PubMed ID: 12048257
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products.
    Liang YJ; Shyu KG; Wang BW; Lai LP
    Cardiology; 2008; 110(3):182-90. PubMed ID: 18057884
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity.
    Staal A; Frith JC; French MH; Swartz J; Güngör T; Harrity TW; Tamasi J; Rogers MJ; Feyen JH
    J Bone Miner Res; 2003 Jan; 18(1):88-96. PubMed ID: 12510809
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages.
    Veillard NR; Braunersreuther V; Arnaud C; Burger F; Pelli G; Steffens S; Mach F
    Atherosclerosis; 2006 Sep; 188(1):51-8. PubMed ID: 16321392
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Non-lipid-related effects of statins.
    Bellosta S; Ferri N; Bernini F; Paoletti R; Corsini A
    Ann Med; 2000 Apr; 32(3):164-76. PubMed ID: 10821323
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.