BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

418 related articles for article (PubMed ID: 22275372)

  • 21. An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses.
    Lee S; Lim MJ; Kim MH; Yu CH; Yun YS; Ahn J; Song JY
    Free Radic Biol Med; 2012 Aug; 53(4):807-16. PubMed ID: 22684019
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Upregulation of NF-E2-related factor-2-dependent glutathione by carnosol provokes a cytoprotective response and enhances cell survival.
    Chen CC; Chen HL; Hsieh CW; Yang YL; Wung BS
    Acta Pharmacol Sin; 2011 Jan; 32(1):62-9. PubMed ID: 21151161
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis.
    Niture SK; Jaiswal AK
    J Biol Chem; 2011 Dec; 286(52):44542-56. PubMed ID: 22072718
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.
    Bloom D; Dhakshinamoorthy S; Jaiswal AK
    Oncogene; 2002 Mar; 21(14):2191-200. PubMed ID: 11948402
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression.
    Kaspar JW; Jaiswal AK
    FASEB J; 2011 Mar; 25(3):1076-87. PubMed ID: 21097520
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants.
    Dhakshinamoorthy S; Jain AK; Bloom DA; Jaiswal AK
    J Biol Chem; 2005 Apr; 280(17):16891-900. PubMed ID: 15734732
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells.
    Son YO; Pratheeshkumar P; Divya SP; Zhang Z; Shi X
    J Biol Chem; 2017 May; 292(20):8315-8330. PubMed ID: 28330870
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Aberrantly elevated redox sensing factor Nrf2 promotes cancer stem cell survival via enhanced transcriptional regulation of ABCG2 and Bcl-2/Bmi-1 genes.
    Jia Y; Chen J; Zhu H; Jia ZH; Cui MH
    Oncol Rep; 2015 Nov; 34(5):2296-304. PubMed ID: 26324021
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Zerumbone protects human skin keratinocytes against UVA-irradiated damages through Nrf2 induction.
    Yang HL; Lee CL; Korivi M; Liao JW; Rajendran P; Wu JJ; Hseu YC
    Biochem Pharmacol; 2018 Feb; 148():130-146. PubMed ID: 29273513
    [TBL] [Abstract][Full Text] [Related]  

  • 30. MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil.
    Shi L; Wu L; Chen Z; Yang J; Chen X; Yu F; Zheng F; Lin X
    Cell Physiol Biochem; 2015; 35(6):2333-48. PubMed ID: 25896253
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Downregulation of Nrf2 by the combination of TRAIL and Valproic acid induces apoptotic cell death of TRAIL-resistant papillary thyroid cancer cells via suppression of Bcl-xL.
    Cha HY; Lee BS; Chang JW; Park JK; Han JH; Kim YS; Shin YS; Byeon HK; Kim CH
    Cancer Lett; 2016 Mar; 372(1):65-74. PubMed ID: 26721202
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The involvement of Nrf2-ARE pathway in regulation of apoptosis in human glioblastoma cell U251.
    Pan H; Wang H; Zhu L; Wang X; Cong Z; Sun K; Fan Y
    Neurol Res; 2013 Jan; 35(1):71-8. PubMed ID: 23006842
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype.
    Singh A; Wu H; Zhang P; Happel C; Ma J; Biswal S
    Mol Cancer Ther; 2010 Aug; 9(8):2365-76. PubMed ID: 20682644
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Topoisomerase inhibitor-induced apoptosis accompanied by down-regulation of Bcl-2 in human lung cancer cells.
    Oizumi S; Isobe H; Ogura S; Ishida T; Yamazaki K; Nishimura M; Kawakami Y; Dosaka-Akita H
    Anticancer Res; 2002; 22(6C):4029-37. PubMed ID: 12553028
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The chalcone compound isosalipurposide (ISPP) exerts a cytoprotective effect against oxidative injury via Nrf2 activation.
    Han JY; Cho SS; Yang JH; Kim KM; Jang CH; Park DE; Bang JS; Jung YS; Ki SH
    Toxicol Appl Pharmacol; 2015 Aug; 287(1):77-85. PubMed ID: 26028482
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Nrf2 knockdown by shRNA inhibits tumor growth and increases efficacy of chemotherapy in cervical cancer.
    Ma X; Zhang J; Liu S; Huang Y; Chen B; Wang D
    Cancer Chemother Pharmacol; 2012 Feb; 69(2):485-94. PubMed ID: 21842204
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Nrf2-Keap1 antioxidant defense and cell survival signaling are upregulated by 17β-estradiol in homocysteine-treated dopaminergic SH-SY5Y cells.
    Chen CS; Tseng YT; Hsu YY; Lo YC
    Neuroendocrinology; 2013; 97(3):232-41. PubMed ID: 22948038
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Nomilin inhibits metastasis via induction of apoptosis and regulates the activation of transcription factors and the cytokine profile in B16F-10 cells.
    Pratheeshkumar P; Raphael TJ; Kuttan G
    Integr Cancer Ther; 2012 Mar; 11(1):48-60. PubMed ID: 21665879
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.
    Zanotto-Filho A; Masamsetti VP; Loranc E; Tonapi SS; Gorthi A; Bernard X; Gonçalves RM; Moreira JC; Chen Y; Bishop AJ
    Mol Cancer Ther; 2016 Dec; 15(12):3000-3014. PubMed ID: 27638861
    [TBL] [Abstract][Full Text] [Related]  

  • 40. HOXC6 is deregulated in human head and neck squamous cell carcinoma and modulates Bcl-2 expression.
    Moon SM; Kim SA; Yoon JH; Ahn SG
    J Biol Chem; 2012 Oct; 287(42):35678-35688. PubMed ID: 22896703
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.