BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 22275515)

  • 1. The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activity.
    Leoh LS; van Heertum B; De Rijck J; Filippova M; Rios-Colon L; Basu A; Martinez SR; Tungteakkhun SS; Filippov V; Christ F; De Leon M; Debyser Z; Casiano CA
    Mol Cancer Res; 2012 Mar; 10(3):378-91. PubMed ID: 22275515
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alternative splicing and caspase-mediated cleavage generate antagonistic variants of the stress oncoprotein LEDGF/p75.
    Brown-Bryan TA; Leoh LS; Ganapathy V; Pacheco FJ; Mediavilla-Varela M; Filippova M; Linkhart TA; Gijsbers R; Debyser Z; Casiano CA
    Mol Cancer Res; 2008 Aug; 6(8):1293-307. PubMed ID: 18708362
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer.
    Basu A; Cajigas-Du Ross CK; Rios-Colon L; Mediavilla-Varela M; Daniels-Wells TR; Leoh LS; Rojas H; Banerjee H; Martinez SR; Acevedo-Martinez S; Casiano CA
    PLoS One; 2016; 11(1):e0146549. PubMed ID: 26771192
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells.
    Ortiz-Hernandez GL; Sanchez-Hernandez ES; Ochoa PT; Elix CC; Alkashgari HR; McMullen JRW; Soto U; Martinez SR; Diaz Osterman CJ; Mahler M; Roy S; Casiano CA
    Cells; 2021 Oct; 10(10):. PubMed ID: 34685704
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75.
    Bartholomeeusen K; De Rijck J; Busschots K; Desender L; Gijsbers R; Emiliani S; Benarous R; Debyser Z; Christ F
    J Mol Biol; 2007 Sep; 372(2):407-21. PubMed ID: 17669426
    [TBL] [Abstract][Full Text] [Related]  

  • 6. LEDGF/p75 TATA-less promoter is driven by the transcription factor Sp1.
    Desfarges S; Abderrahmani A; Hernàndez-Novoa B; Munoz M; Ciuffi A
    J Mol Biol; 2011 Nov; 414(2):177-93. PubMed ID: 22019592
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells.
    Maertens G; Cherepanov P; Pluymers W; Busschots K; De Clercq E; Debyser Z; Engelborghs Y
    J Biol Chem; 2003 Aug; 278(35):33528-39. PubMed ID: 12796494
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SUMOylation of the lens epithelium-derived growth factor/p75 attenuates its transcriptional activity on the heat shock protein 27 promoter.
    Bueno MT; Garcia-Rivera JA; Kugelman JR; Morales E; Rosas-Acosta G; Llano M
    J Mol Biol; 2010 Jun; 399(2):221-39. PubMed ID: 20382164
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dynamics of the ternary complex formed by c-Myc interactor JPO2, transcriptional co-activator LEDGF/p75, and chromatin.
    Hendrix J; van Heertum B; Vanstreels E; Daelemans D; De Rijck J
    J Biol Chem; 2014 May; 289(18):12494-506. PubMed ID: 24634210
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcriptional protein Sp1 regulates LEDGF transcription by directly interacting with its cis-elements in GC-rich region of TATA-less gene promoter.
    Singh DP; Bhargavan B; Chhunchha B; Kubo E; Kumar A; Fatma N
    PLoS One; 2012; 7(5):e37012. PubMed ID: 22615874
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis in vitro.
    Huang TS; Myklebust LM; Kjarland E; Gjertsen BT; Pendino F; Bruserud Ø; Døskeland SO; Lillehaug JR
    Mol Cancer; 2007 Apr; 6():31. PubMed ID: 17451600
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.
    Morchikh M; Naughtin M; Di Nunzio F; Xavier J; Charneau P; Jacob Y; Lavigne M
    PLoS One; 2013; 8(11):e81217. PubMed ID: 24312278
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pathway specific gene expression profiling reveals oxidative stress genes potentially regulated by transcription co-activator LEDGF/p75 in prostate cancer cells.
    Basu A; Drame A; Muñoz R; Gijsbers R; Debyser Z; De Leon M; Casiano CA
    Prostate; 2012 May; 72(6):597-611. PubMed ID: 21796653
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of the stress response oncoprotein LEDGF/p75 in human cancer: a study of 21 tumor types.
    Basu A; Rojas H; Banerjee H; Cabrera IB; Perez KY; De León M; Casiano CA
    PLoS One; 2012; 7(1):e30132. PubMed ID: 22276150
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting the stress oncoprotein LEDGF/p75 to sensitize chemoresistant prostate cancer cells to taxanes.
    Ríos-Colón L; Cajigas-Du Ross CK; Basu A; Elix C; Alicea-Polanco I; Sanchez TW; Radhakrishnan V; Chen CS; Casiano CA
    Oncotarget; 2017 Apr; 8(15):24915-24931. PubMed ID: 28212536
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptional regulation of vascular endothelial growth factor C by oxidative and thermal stress is mediated by lens epithelium-derived growth factor/p75.
    Cohen B; Addadi Y; Sapoznik S; Meir G; Kalchenko V; Harmelin A; Ben-Dor S; Neeman M
    Neoplasia; 2009 Sep; 11(9):921-33. PubMed ID: 19724686
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase.
    Cherepanov P; Devroe E; Silver PA; Engelman A
    J Biol Chem; 2004 Nov; 279(47):48883-92. PubMed ID: 15371438
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA binding domains and nuclear localization signal of LEDGF: contribution of two helix-turn-helix (HTH)-like domains and a stretch of 58 amino acids of the N-terminal to the trans-activation potential of LEDGF.
    Singh DP; Kubo E; Takamura Y; Shinohara T; Kumar A; Chylack LT; Fatma N
    J Mol Biol; 2006 Jan; 355(3):379-94. PubMed ID: 16318853
    [TBL] [Abstract][Full Text] [Related]  

  • 19. LEDGF gene silencing impairs the tumorigenicity of prostate cancer DU145 cells by abating the expression of Hsp27 and activation of the Akt/ERK signaling pathway.
    Bhargavan B; Fatma N; Chhunchha B; Singh V; Kubo E; Singh DP
    Cell Death Dis; 2012 May; 3(5):e316. PubMed ID: 22647853
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase.
    Llano M; Delgado S; Vanegas M; Poeschla EM
    J Biol Chem; 2004 Dec; 279(53):55570-7. PubMed ID: 15475359
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.