BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 22276570)

  • 1. Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo.
    Carta F; Aggarwal M; Maresca A; Scozzafava A; McKenna R; Masini E; Supuran CT
    J Med Chem; 2012 Feb; 55(4):1721-30. PubMed ID: 22276570
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo.
    Carta F; Akdemir A; Scozzafava A; Masini E; Supuran CT
    J Med Chem; 2013 Jun; 56(11):4691-700. PubMed ID: 23647428
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.
    Bozdag M; Carta F; Vullo D; Akdemir A; Isik S; Lanzi C; Scozzafava A; Masini E; Supuran CT
    Bioorg Med Chem; 2015 May; 23(10):2368-76. PubMed ID: 25846066
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Monothiocarbamates Strongly Inhibit Carbonic Anhydrases in Vitro and Possess Intraocular Pressure Lowering Activity in an Animal Model of Glaucoma.
    Vullo D; Durante M; Di Leva FS; Cosconati S; Masini E; Scozzafava A; Novellino E; Supuran CT; Carta F
    J Med Chem; 2016 Jun; 59(12):5857-67. PubMed ID: 27253845
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase.
    Bozdag M; Carta F; Vullo D; Isik S; AlOthman Z; Osman SM; Scozzafava A; Supuran CT
    J Enzyme Inhib Med Chem; 2016; 31(1):132-6. PubMed ID: 25669351
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recent advances in the discovery of zinc-binding motifs for the development of carbonic anhydrase inhibitors.
    Winum JY; Supuran CT
    J Enzyme Inhib Med Chem; 2015 Apr; 30(2):321-4. PubMed ID: 24939097
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations.
    Carta F; Aggarwal M; Maresca A; Scozzafava A; McKenna R; Supuran CT
    Chem Commun (Camb); 2012 Feb; 48(13):1868-70. PubMed ID: 22218610
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis.
    Maresca A; Carta F; Vullo D; Supuran CT
    J Enzyme Inhib Med Chem; 2013 Apr; 28(2):407-11. PubMed ID: 22145736
    [TBL] [Abstract][Full Text] [Related]  

  • 9. More effective dithiocarbamate derivatives inhibiting carbonic anhydrases, generated by QSAR and computational design.
    Avram S; Milac AL; Carta F; Supuran CT
    J Enzyme Inhib Med Chem; 2013 Apr; 28(2):350-9. PubMed ID: 23116520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups.
    Bozdag M; Ferraroni M; Carta F; Vullo D; Lucarini L; Orlandini E; Rossello A; Nuti E; Scozzafava A; Masini E; Supuran CT
    J Med Chem; 2014 Nov; 57(21):9152-67. PubMed ID: 25310626
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents.
    Chiaramonte N; Bua S; Ferraroni M; Nocentini A; Bonardi A; Bartolucci G; Durante M; Lucarini L; Chiapponi D; Dei S; Manetti D; Teodori E; Gratteri P; Masini E; Supuran CT; Romanelli MN
    Eur J Med Chem; 2018 May; 151():363-375. PubMed ID: 29635168
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma.
    Alafeefy AM; Carta F; Ceruso M; Al-Tamimi AM; Al-Kahtani AA; Supuran CT
    Bioorg Med Chem; 2016 Mar; 24(6):1402-7. PubMed ID: 26875933
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata.
    Monti SM; Maresca A; Viparelli F; Carta F; De Simone G; Mühlschlegel FA; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2012 Jan; 22(2):859-62. PubMed ID: 22209456
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-based drug discovery of carbonic anhydrase inhibitors.
    Supuran CT
    J Enzyme Inhib Med Chem; 2012 Dec; 27(6):759-72. PubMed ID: 22468747
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations.
    Nocentini A; Ferraroni M; Carta F; Ceruso M; Gratteri P; Lanzi C; Masini E; Supuran CT
    J Med Chem; 2016 Dec; 59(23):10692-10704. PubMed ID: 27933963
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.
    Leitans J; Sprudza A; Tanc M; Vozny I; Zalubovskis R; Tars K; Supuran CT
    Bioorg Med Chem; 2013 Sep; 21(17):5130-8. PubMed ID: 23859774
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dithiocarbamates effectively inhibit the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa.
    Vullo D; Del Prete S; Nocentini A; Osman SM; AlOthman Z; Capasso C; Bozdag M; Carta F; Gratteri P; Supuran CT
    Bioorg Med Chem; 2017 Feb; 25(3):1260-1265. PubMed ID: 28057408
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dithiocarbamates effectively inhibit the α-carbonic anhydrase from
    Giovannuzzi S; Abutaleb NS; Hewitt CS; Carta F; Nocentini A; Seleem MN; Flaherty DP; Supuran CT
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):1-8. PubMed ID: 34894954
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.
    Żołnowska B; Sławiński J; Pogorzelska A; Chojnacki J; Vullo D; Supuran CT
    Eur J Med Chem; 2014 Jan; 71():135-47. PubMed ID: 24291567
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation.
    Moi D; Nocentini A; Deplano A; Balboni G; Supuran CT; Onnis V
    Eur J Med Chem; 2019 Nov; 182():111638. PubMed ID: 31472471
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.