141 related articles for article (PubMed ID: 22279052)
1. Models to predict unbound intracellular drug concentrations in the presence of transporters.
Korzekwa KR; Nagar S; Tucker J; Weiskircher EA; Bhoopathy S; Hidalgo IJ
Drug Metab Dispos; 2012 May; 40(5):865-76. PubMed ID: 22279052
[TBL] [Abstract][Full Text] [Related]
2. Compartmental models for apical efflux by P-glycoprotein--part 1: evaluation of model complexity.
Nagar S; Tucker J; Weiskircher EA; Bhoopathy S; Hidalgo IJ; Korzekwa K
Pharm Res; 2014 Feb; 31(2):347-59. PubMed ID: 24019023
[TBL] [Abstract][Full Text] [Related]
3. Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity.
Taub ME; Podila L; Ely D; Almeida I
Drug Metab Dispos; 2005 Nov; 33(11):1679-87. PubMed ID: 16093365
[TBL] [Abstract][Full Text] [Related]
4. In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system.
Feng B; Mills JB; Davidson RE; Mireles RJ; Janiszewski JS; Troutman MD; de Morais SM
Drug Metab Dispos; 2008 Feb; 36(2):268-75. PubMed ID: 17962372
[TBL] [Abstract][Full Text] [Related]
5. If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?
Lumen AA; Acharya P; Polli JW; Ayrton A; Ellens H; Bentz J
Drug Metab Dispos; 2010 Feb; 38(2):260-9. PubMed ID: 19889884
[TBL] [Abstract][Full Text] [Related]
6. Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).
Nies AT; Herrmann E; Brom M; Keppler D
Naunyn Schmiedebergs Arch Pharmacol; 2008 Feb; 376(6):449-61. PubMed ID: 18157518
[TBL] [Abstract][Full Text] [Related]
7. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2- Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration.
Liu H; Yu N; Lu S; Ito S; Zhang X; Prasad B; He E; Lu X; Li Y; Wang F; Xu H; An G; Unadkat JD; Kusuhara H; Sugiyama Y; Sahi J
Drug Metab Dispos; 2015 Jul; 43(7):1008-18. PubMed ID: 25908246
[TBL] [Abstract][Full Text] [Related]
8. Functional characterization of monocarboxylic acid, large neutral amino acid, bile acid and peptide transporters, and P-glycoprotein in MDCK and Caco-2 cells.
Putnam WS; Ramanathan S; Pan L; Takahashi LH; Benet LZ
J Pharm Sci; 2002 Dec; 91(12):2622-35. PubMed ID: 12434407
[TBL] [Abstract][Full Text] [Related]
9. Expression and functional activity of P-glycoprotein in passaged primary human nasal epithelial cell monolayers cultured by the air-liquid interface method for nasal drug transport study.
Cho HJ; Choi MK; Lin H; Kim JS; Chung SJ; Shim CK; Kim DD
J Pharm Pharmacol; 2011 Mar; 63(3):385-91. PubMed ID: 21749386
[TBL] [Abstract][Full Text] [Related]
10. Functional role of P-glycoprotein in limiting intestinal absorption of drugs: contribution of passive permeability to P-glycoprotein mediated efflux transport.
Varma MV; Sateesh K; Panchagnula R
Mol Pharm; 2005; 2(1):12-21. PubMed ID: 15804173
[TBL] [Abstract][Full Text] [Related]
11. Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs.
Dahan A; Amidon GL
Mol Pharm; 2009; 6(1):19-28. PubMed ID: 19248230
[TBL] [Abstract][Full Text] [Related]
12. Permeability, transport, and metabolism of solutes in Caco-2 cell monolayers: a theoretical study.
Sun H; Pang KS
Drug Metab Dispos; 2008 Jan; 36(1):102-23. PubMed ID: 17932224
[TBL] [Abstract][Full Text] [Related]
13. A structural model for the mass action kinetic analysis of P-gp mediated transport through confluent cell monolayers.
Bentz J; Ellens H
Methods Mol Biol; 2014; 1113():289-316. PubMed ID: 24523118
[TBL] [Abstract][Full Text] [Related]
14. Bidirectional transport of rhodamine 123 and Hoechst 33342, fluorescence probes of the binding sites on P-glycoprotein, across MDCK-MDR1 cell monolayers.
Tang F; Ouyang H; Yang JZ; Borchardt RT
J Pharm Sci; 2004 May; 93(5):1185-94. PubMed ID: 15067695
[TBL] [Abstract][Full Text] [Related]
15. Kinetic analysis of human and canine P-glycoprotein-mediated drug transport in MDR1-MDCK cell model: approaches to reduce false-negative substrate classification.
Li J; Wang Y; Hidalgo IJ
J Pharm Sci; 2013 Sep; 102(9):3436-46. PubMed ID: 23558561
[TBL] [Abstract][Full Text] [Related]
16. Existence of a p-glycoprotein drug efflux pump in cultured rabbit conjunctival epithelial cells.
Saha P; Yang JJ; Lee VH
Invest Ophthalmol Vis Sci; 1998 Jun; 39(7):1221-6. PubMed ID: 9620082
[TBL] [Abstract][Full Text] [Related]
17. Stereoselective and concentration-dependent polarized epithelial permeability of a series of phosphoramidate triester prodrugs of d4T: an in vitro study in Caco-2 and Madin-Darby canine kidney cell monolayers.
Siccardi D; Kandalaft LE; Gumbleton M; McGuigan C
J Pharmacol Exp Ther; 2003 Dec; 307(3):1112-9. PubMed ID: 14557377
[TBL] [Abstract][Full Text] [Related]
18. Modulation of the cellular accumulation and intracellular activity of daptomycin towards phagocytized Staphylococcus aureus by the P-glycoprotein (MDR1) efflux transporter in human THP-1 macrophages and madin-darby canine kidney cells.
Lemaire S; Van Bambeke F; Mingeot-Leclercq MP; Tulkens PM
Antimicrob Agents Chemother; 2007 Aug; 51(8):2748-57. PubMed ID: 17548493
[TBL] [Abstract][Full Text] [Related]
19. Conferone from Ferula schtschurowskiana enhances vinblastine cytotoxicity in MDCK-MDR1 cells by competitively inhibiting P-glycoprotein transport.
Barthomeuf C; Demeule M; Grassi J; Saidkhodjaev A; Beliveau R
Planta Med; 2006 Jun; 72(7):634-9. PubMed ID: 16739070
[TBL] [Abstract][Full Text] [Related]
20. Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein.
Döppenschmitt S; Spahn-Langguth H; Regårdh CG; Langguth P
J Pharm Sci; 1999 Oct; 88(10):1067-72. PubMed ID: 10514357
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]