418 related articles for article (PubMed ID: 22283547)
1. Structures of Aβ17-42 trimers in isolation and with five small-molecule drugs using a hierarchical computational procedure.
Chebaro Y; Jiang P; Zang T; Mu Y; Nguyen PH; Mousseau N; Derreumaux P
J Phys Chem B; 2012 Jul; 116(29):8412-22. PubMed ID: 22283547
[TBL] [Abstract][Full Text] [Related]
2. Understanding amyloid fibril nucleation and aβ oligomer/drug interactions from computer simulations.
Nguyen P; Derreumaux P
Acc Chem Res; 2014 Feb; 47(2):603-11. PubMed ID: 24368046
[TBL] [Abstract][Full Text] [Related]
3. Molecular structure of the NQTrp inhibitor with the Alzheimer Aβ1-28 monomer.
Tarus B; Nguyen PH; Berthoumieu O; Faller P; Doig AJ; Derreumaux P
Eur J Med Chem; 2015 Feb; 91():43-50. PubMed ID: 25011560
[TBL] [Abstract][Full Text] [Related]
4. Methylations of tryptophan-modified naphthoquinone affect its inhibitory potential toward Aβ aggregation.
Scherzer-Attali R; Convertino M; Pellarin R; Gazit E; Segal D; Caflisch A
J Phys Chem B; 2013 Feb; 117(6):1780-9. PubMed ID: 23259849
[TBL] [Abstract][Full Text] [Related]
5. The inhibitory mechanism of a fullerene derivative against amyloid-β peptide aggregation: an atomistic simulation study.
Sun Y; Qian Z; Wei G
Phys Chem Chem Phys; 2016 May; 18(18):12582-91. PubMed ID: 27091578
[TBL] [Abstract][Full Text] [Related]
6. The role of phenolic OH groups of flavonoid compounds with H-bond formation ability to suppress amyloid mature fibrils by destabilizing β-sheet conformation of monomeric Aβ17-42.
Andarzi Gargari S; Barzegar A; Tarinejad A
PLoS One; 2018; 13(6):e0199541. PubMed ID: 29953467
[TBL] [Abstract][Full Text] [Related]
7. Molecular mechanism of the inhibition of EGCG on the Alzheimer Aβ(1-42) dimer.
Zhang T; Zhang J; Derreumaux P; Mu Y
J Phys Chem B; 2013 Apr; 117(15):3993-4002. PubMed ID: 23537203
[TBL] [Abstract][Full Text] [Related]
8. Atomic and dynamic insights into the beneficial effect of the 1,4-naphthoquinon-2-yl-L-tryptophan inhibitor on Alzheimer's Aβ1-42 dimer in terms of aggregation and toxicity.
Zhang T; Xu W; Mu Y; Derreumaux P
ACS Chem Neurosci; 2014 Feb; 5(2):148-59. PubMed ID: 24246047
[TBL] [Abstract][Full Text] [Related]
9. The effect of curcumin on the stability of Aβ dimers.
Zhao LN; Chiu SW; Benoit J; Chew LY; Mu Y
J Phys Chem B; 2012 Jun; 116(25):7428-35. PubMed ID: 22690789
[TBL] [Abstract][Full Text] [Related]
10. Determining binding sites of polycyclic aromatic small molecule-based amyloid-beta peptide aggregation modulators using sequence-specific antibodies.
Irwin JA; Edward Wong H; Kwon I
Anal Biochem; 2015 Feb; 470():61-70. PubMed ID: 25449301
[TBL] [Abstract][Full Text] [Related]
11. Scrutiny of the mechanism of small molecule inhibitor preventing conformational transition of amyloid-β
Shuaib S; Goyal B
J Biomol Struct Dyn; 2018 Feb; 36(3):663-678. PubMed ID: 28162045
[TBL] [Abstract][Full Text] [Related]
12. Molecular dynamics simulations of Aβ fibril interactions with β-sheet breaker peptides.
Bruce NJ; Chen D; Dastidar SG; Marks GE; Schein CH; Bryce RA
Peptides; 2010 Nov; 31(11):2100-8. PubMed ID: 20691234
[TBL] [Abstract][Full Text] [Related]
13. Virtual and In Vitro Screens Reveal a Potential Pharmacophore that Avoids the Fibrillization of Aβ1-42.
Hernández-Rodríguez M; Correa-Basurto J; Nicolás-Vázquez MI; Miranda-Ruvalcaba R; Benítez-Cardoza CG; Reséndiz-Albor AA; Méndez-Méndez JV; Rosales-Hernández MC
PLoS One; 2015; 10(7):e0130263. PubMed ID: 26172152
[TBL] [Abstract][Full Text] [Related]
14. Effects of G33A and G33I mutations on the structures of monomer and dimer of the amyloid-β fragment 29-42 by replica exchange molecular dynamics simulations.
Lu Y; Wei G; Derreumaux P
J Phys Chem B; 2011 Feb; 115(5):1282-8. PubMed ID: 21186801
[TBL] [Abstract][Full Text] [Related]
15. Thioflavin T templates amyloid β(1-40) conformation and aggregation pathway.
Di Carlo MG; Minicozzi V; Foderà V; Militello V; Vetri V; Morante S; Leone M
Biophys Chem; 2015 Nov; 206():1-11. PubMed ID: 26100600
[TBL] [Abstract][Full Text] [Related]
16. Naphthoquinone-tyrptophan reduces neurotoxic Aβ*56 levels and improves cognition in Alzheimer's disease animal model.
Scherzer-Attali R; Farfara D; Cooper I; Levin A; Ben-Romano T; Trudler D; Vientrov M; Shaltiel-Karyo R; Shalev DE; Segev-Amzaleg N; Gazit E; Segal D; Frenkel D
Neurobiol Dis; 2012 Jun; 46(3):663-72. PubMed ID: 22449754
[TBL] [Abstract][Full Text] [Related]
17. The structure of the Alzheimer amyloid beta 10-35 peptide probed through replica-exchange molecular dynamics simulations in explicit solvent.
Baumketner A; Shea JE
J Mol Biol; 2007 Feb; 366(1):275-85. PubMed ID: 17166516
[TBL] [Abstract][Full Text] [Related]
18. Structural diversity of the soluble trimers of the human amylin(20-29) peptide revealed by molecular dynamics simulations.
Mo Y; Lu Y; Wei G; Derreumaux P
J Chem Phys; 2009 Mar; 130(12):125101. PubMed ID: 19334894
[TBL] [Abstract][Full Text] [Related]
19. A computational study of self-assembled hexapeptide inhibitors against amyloid-β (Aβ) aggregation.
Qiao Y; Zhang M; Liang Y; Zheng J; Liang G
Phys Chem Chem Phys; 2016 Dec; 19(1):155-166. PubMed ID: 27929168
[TBL] [Abstract][Full Text] [Related]
20. Structures and thermodynamics of Alzheimer's amyloid-beta Abeta(16-35) monomer and dimer by replica exchange molecular dynamics simulations: implication for full-length Abeta fibrillation.
Chebaro Y; Mousseau N; Derreumaux P
J Phys Chem B; 2009 May; 113(21):7668-75. PubMed ID: 19415895
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]