BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 22285490)

  • 1. LY294002 inhibits TLR3/4-mediated IFN-β production via inhibition of IRF3 activation with a PI3K-independent mechanism.
    Zhao W; Qi J; Wang L; Zhang M; Wang P; Gao C
    FEBS Lett; 2012 Mar; 586(6):705-10. PubMed ID: 22285490
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3- and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFN-beta promoter.
    Zhao W; Wang L; Zhang M; Wang P; Zhang L; Yuan C; Qi J; Qiao Y; Kuo PC; Gao C
    J Biol Chem; 2011 Feb; 286(7):5519-28. PubMed ID: 21148557
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of Toll-like receptor 3 and 4.
    Aksoy E; Vanden Berghe W; Detienne S; Amraoui Z; Fitzgerald KA; Haegeman G; Goldman M; Willems F
    Eur J Immunol; 2005 Jul; 35(7):2200-9. PubMed ID: 15940673
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphatidylinositol-3-kinase and Akt are required for RIG-I-mediated anti-viral signalling through cross-talk with IPS-1.
    Yeon SH; Song MJ; Kang HR; Lee JY
    Immunology; 2015 Feb; 144(2):312-20. PubMed ID: 25158146
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Annexin-A1 regulates TLR-mediated IFN-β production through an interaction with TANK-binding kinase 1.
    Bist P; Shu S; Lee H; Arora S; Nair S; Lim JY; Dayalan J; Gasser S; Biswas SK; Fairhurst AM; Lim LH
    J Immunol; 2013 Oct; 191(8):4375-82. PubMed ID: 24048896
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction.
    Dong LW; Kong XN; Yan HX; Yu LX; Chen L; Yang W; Liu Q; Huang DD; Wu MC; Wang HY
    Mol Immunol; 2008 Jun; 45(11):3025-35. PubMed ID: 18471880
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like.
    Siednienko J; Halle A; Nagpal K; Golenbock DT; Miggin SM
    Eur J Immunol; 2010 Nov; 40(11):3150-60. PubMed ID: 20957750
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential effects of LY294002 and wortmannin on inducible nitric oxide synthase expression in glomerular mesangial cells.
    Tsai KD; Chang WW; Lin CC; Hsu SC; Lee YJ; Chen W; Shieh JC; Lin TH
    Int Immunopharmacol; 2012 Mar; 12(3):471-80. PubMed ID: 22240122
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The inducible nitric-oxide synthase (iNOS)/Src axis mediates Toll-like receptor 3 tyrosine 759 phosphorylation and enhances its signal transduction, leading to interferon-β synthesis in macrophages.
    Hsieh MY; Chang MY; Chen YJ; Li YK; Chuang TH; Yu GY; Cheung CH; Chen HC; Maa MC; Leu TH
    J Biol Chem; 2014 Mar; 289(13):9208-20. PubMed ID: 24526685
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DOK3 is required for IFN-β production by enabling TRAF3/TBK1 complex formation and IRF3 activation.
    Kim SS; Lee KG; Chin CS; Ng SK; Pereira NA; Xu S; Lam KP
    J Immunol; 2014 Jul; 193(2):840-8. PubMed ID: 24929003
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-β and RANTES production.
    Siednienko J; Gajanayake T; Fitzgerald KA; Moynagh P; Miggin SM
    J Immunol; 2011 Feb; 186(4):2514-22. PubMed ID: 21248248
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IRF3 and ERK MAP-kinases control nitric oxide production from macrophages in response to poly-I:C.
    Moore TC; Petro TM
    FEBS Lett; 2013 Sep; 587(18):3014-20. PubMed ID: 23892079
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.
    Yamamoto M; Sato S; Hemmi H; Hoshino K; Kaisho T; Sanjo H; Takeuchi O; Sugiyama M; Okabe M; Takeda K; Akira S
    Science; 2003 Aug; 301(5633):640-3. PubMed ID: 12855817
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of phosphatidylinositol 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects of rapamycin, Ly294002, and wortmannin on nitric oxide production.
    Salh B; Wagey R; Marotta A; Tao JS; Pelech S
    J Immunol; 1998 Dec; 161(12):6947-54. PubMed ID: 9862729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LY294002 inhibits LPS-induced NO production through a inhibition of NF-kappaB activation: independent mechanism of phosphatidylinositol 3-kinase.
    Kim YH; Choi KH; Park JW; Kwon TK
    Immunol Lett; 2005 Jun; 99(1):45-50. PubMed ID: 15894110
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein kinase Calpha is involved in interferon regulatory factor 3 activation and type I interferon-beta synthesis.
    Johnson J; Albarani V; Nguyen M; Goldman M; Willems F; Aksoy E
    J Biol Chem; 2007 May; 282(20):15022-32. PubMed ID: 17296604
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Signaling in lipopolysaccharide-induced stabilization of formyl peptide receptor 1 mRNA in mouse peritoneal macrophages.
    Mandal P; Hamilton T
    J Immunol; 2007 Feb; 178(4):2542-8. PubMed ID: 17277163
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MLN4924, a First-in-Class NEDD8-Activating Enzyme Inhibitor, Attenuates IFN-β Production.
    Song H; Huai W; Yu Z; Wang W; Zhao J; Zhang L; Zhao W
    J Immunol; 2016 Apr; 196(7):3117-23. PubMed ID: 26895833
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Toll-like receptor 3-elicited MAPK activation induces stabilization of interferon-β mRNA.
    Johnsen IB; Nguyen TT; Bergstrøm B; Lien E; Anthonsen MW
    Cytokine; 2012 Mar; 57(3):337-46. PubMed ID: 22200507
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of inhibition of lipopolysaccharide-induced interferon-β production by 2-aminopurine.
    Sugiyama T; Gotou T; Moriyama K; Kajiura N; Hasegawa T; Tomida J; Takahashi K; Komatsu T; Ueda H; Sato K; Tokoro S; Neri P; Mori H
    Mol Immunol; 2012 Oct; 52(3-4):299-304. PubMed ID: 22750230
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.