BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 22285861)

  • 1. Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells.
    Guo Z; Zhou Y; Evers BM; Wang Q
    Biochem Biophys Res Commun; 2012 Feb; 418(2):426-32. PubMed ID: 22285861
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.
    Koo J; Wu X; Mao Z; Khuri FR; Sun SY
    J Biol Chem; 2015 May; 290(22):14120-9. PubMed ID: 25897075
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Recombinant human adenovirus-p53 injection induced apoptosis in hepatocellular carcinoma cell lines mediated by p53-Fbxw7 pathway, which controls c-Myc and cyclin E.
    Tu K; Zheng X; Zhou Z; Li C; Zhang J; Gao J; Yao Y; Liu Q
    PLoS One; 2013; 8(7):e68574. PubMed ID: 23840897
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation mechanism of Fbxw7-related signaling pathways (Review).
    Zhou Z; He C; Wang J
    Oncol Rep; 2015 Nov; 34(5):2215-24. PubMed ID: 26324296
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Plk2 promotes tumor growth and inhibits apoptosis by targeting Fbxw7/Cyclin E in colorectal cancer.
    Ou B; Zhao J; Guan S; Wangpu X; Zhu C; Zong Y; Ma J; Sun J; Zheng M; Feng H; Lu A
    Cancer Lett; 2016 Oct; 380(2):457-466. PubMed ID: 27423313
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTOR Complex 2 Stabilizes Mcl-1 Protein by Suppressing Its Glycogen Synthase Kinase 3-Dependent and SCF-FBXW7-Mediated Degradation.
    Koo J; Yue P; Deng X; Khuri FR; Sun SY
    Mol Cell Biol; 2015 Jul; 35(13):2344-55. PubMed ID: 25918246
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation.
    Kanei-Ishii C; Nomura T; Takagi T; Watanabe N; Nakayama KI; Ishii S
    J Biol Chem; 2008 Nov; 283(45):30540-8. PubMed ID: 18765672
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation.
    Xi Z; Yao M; Li Y; Xie C; Holst J; Liu T; Cai S; Lao Y; Tan H; Xu HX; Dong Q
    Cell Death Dis; 2016 Jun; 7(6):e2252. PubMed ID: 27253416
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.
    Fujii Y; Yada M; Nishiyama M; Kamura T; Takahashi H; Tsunematsu R; Susaki E; Nakagawa T; Matsumoto A; Nakayama KI
    Cancer Sci; 2006 Aug; 97(8):729-36. PubMed ID: 16863506
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.
    Xu Y; Sengupta T; Kukreja L; Minella AC
    J Biol Chem; 2010 Nov; 285(45):34439-46. PubMed ID: 20826802
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T; Hattori T; Kitagawa K; Uchida C; Kotake Y; Kosugi I; Oda T; Kitagawa M
    J Biol Chem; 2009 Oct; 284(41):27766-27779. PubMed ID: 19679664
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MYC is a critical target of FBXW7.
    Sato M; Rodriguez-Barrueco R; Yu J; Do C; Silva JM; Gautier J
    Oncotarget; 2015 Feb; 6(5):3292-305. PubMed ID: 25669969
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 14. E3 ubiquitin ligase FBW7α inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E.
    Li M; Ouyang L; Zheng Z; Xiang D; Ti A; Li L; Dan Y; Yu C; Li W
    Oncol Rep; 2017 Mar; 37(3):1627-1636. PubMed ID: 28184929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.
    Tron AE; Arai T; Duda DM; Kuwabara H; Olszewski JL; Fujiwara Y; Bahamon BN; Signoretti S; Schulman BA; DeCaprio JA
    Mol Cell; 2012 Apr; 46(1):67-78. PubMed ID: 22405651
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FBXW7 acts as an independent prognostic marker and inhibits tumor growth in human osteosarcoma.
    Li Z; Xiao J; Hu K; Wang G; Li M; Zhang J; Cheng G
    Int J Mol Sci; 2015 Jan; 16(2):2294-306. PubMed ID: 25622249
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.
    King B; Trimarchi T; Reavie L; Xu L; Mullenders J; Ntziachristos P; Aranda-Orgilles B; Perez-Garcia A; Shi J; Vakoc C; Sandy P; Shen SS; Ferrando A; Aifantis I
    Cell; 2013 Jun; 153(7):1552-66. PubMed ID: 23791182
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Circadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer.
    Fang L; Yang Z; Zhou J; Tung JY; Hsiao CD; Wang L; Deng Y; Wang P; Wang J; Lee MH
    Mol Cancer Ther; 2015 Jun; 14(6):1476-87. PubMed ID: 25855785
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of mTOR complex 2 induces GSK3/FBXW7-dependent degradation of sterol regulatory element-binding protein 1 (SREBP1) and suppresses lipogenesis in cancer cells.
    Li S; Oh YT; Yue P; Khuri FR; Sun SY
    Oncogene; 2016 Feb; 35(5):642-50. PubMed ID: 25893295
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Plk2 regulates centriole duplication through phosphorylation-mediated degradation of Fbxw7 (human Cdc4).
    Cizmecioglu O; Krause A; Bahtz R; Ehret L; Malek N; Hoffmann I
    J Cell Sci; 2012 Feb; 125(Pt 4):981-92. PubMed ID: 22399798
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.