These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 22286872)

  • 1. The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance.
    Andersson HS; Figueredo SM; Haugaard-Kedström LM; Bengtsson E; Daly NL; Qu X; Craik DJ; Ouellette AJ; Rosengren KJ
    Amino Acids; 2012 Oct; 43(4):1471-83. PubMed ID: 22286872
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.
    Rosengren KJ; Daly NL; Fornander LM; Jönsson LM; Shirafuji Y; Qu X; Vogel HJ; Ouellette AJ; Craik DJ
    J Biol Chem; 2006 Sep; 281(38):28068-78. PubMed ID: 16857681
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4.
    Maemoto A; Qu X; Rosengren KJ; Tanabe H; Henschen-Edman A; Craik DJ; Ouellette AJ
    J Biol Chem; 2004 Oct; 279(42):44188-96. PubMed ID: 15297466
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity determinants in paneth cell alpha-defensins: loss-of-function in mouse cryptdin-4 by charge-reversal at arginine residue positions.
    Tanabe H; Qu X; Weeks CS; Cummings JE; Kolusheva S; Walsh KB; Jelinek R; Vanderlick TK; Selsted ME; Ouellette AJ
    J Biol Chem; 2004 Mar; 279(12):11976-83. PubMed ID: 14702345
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anionic amino acids near the pro-alpha-defensin N terminus mediate inhibition of bactericidal activity in mouse pro-cryptdin-4.
    Figueredo SM; Weeks CS; Young SK; Ouellette AJ
    J Biol Chem; 2009 Mar; 284(11):6826-31. PubMed ID: 19106102
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Matrix metalloproteinase-7 activation of mouse paneth cell pro-alpha-defensins: SER43 down arrow ILE44 proteolysis enables membrane-disruptive activity.
    Weeks CS; Tanabe H; Cummings JE; Crampton SP; Sheynis T; Jelinek R; Vanderlick TK; Cocco MJ; Ouellette AJ
    J Biol Chem; 2006 Sep; 281(39):28932-42. PubMed ID: 16822871
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The conserved salt bridge in human alpha-defensin 5 is required for its precursor processing and proteolytic stability.
    Rajabi M; de Leeuw E; Pazgier M; Li J; Lubkowski J; Lu W
    J Biol Chem; 2008 Aug; 283(31):21509-18. PubMed ID: 18499668
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biosynthesis and antimicrobial evaluation of backbone-cyclized α-defensins.
    Garcia AE; Tai KP; Puttamadappa SS; Shekhtman A; Ouellette AJ; Camarero JA
    Biochemistry; 2011 Dec; 50(48):10508-19. PubMed ID: 22040603
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Electropositive charge in alpha-defensin bactericidal activity: functional effects of Lys-for-Arg substitutions vary with the peptide primary structure.
    Llenado RA; Weeks CS; Cocco MJ; Ouellette AJ
    Infect Immun; 2009 Nov; 77(11):5035-43. PubMed ID: 19737896
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Why is the Arg5-Glu13 salt bridge conserved in mammalian alpha-defensins?
    Wu Z; Li X; de Leeuw E; Ericksen B; Lu W
    J Biol Chem; 2005 Dec; 280(52):43039-47. PubMed ID: 16246847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of bactericidal activity is maintained in a mouse alpha-defensin precursor with proregion truncations.
    Figueredo SM; Ouellette AJ
    Peptides; 2010 Jan; 31(1):9-15. PubMed ID: 19837119
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions of mouse Paneth cell alpha-defensins and alpha-defensin precursors with membranes. Prosegment inhibition of peptide association with biomimetic membranes.
    Satchell DP; Sheynis T; Shirafuji Y; Kolusheva S; Ouellette AJ; Jelinek R
    J Biol Chem; 2003 Apr; 278(16):13838-46. PubMed ID: 12574157
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Solution structure of cryptdin-4, a mouse paneth cell alpha-defensin.
    Jing W; Hunter HN; Tanabe H; Ouellette AJ; Vogel HJ
    Biochemistry; 2004 Dec; 43(50):15759-66. PubMed ID: 15595831
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bactericidal activity of mouse α-defensin cryptdin-4 predominantly affects noncommensal bacteria.
    Masuda K; Sakai N; Nakamura K; Yoshioka S; Ayabe T
    J Innate Immun; 2011; 3(3):315-26. PubMed ID: 21099205
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Quantitative interactions between cryptdin-4 amino terminal variants and membranes.
    Satchell DP; Sheynis T; Kolusheva S; Cummings J; Vanderlick TK; Jelinek R; Selsted ME; Ouellette AJ
    Peptides; 2003 Nov; 24(11):1795-805. PubMed ID: 15019212
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of alpha-defensin bactericidal action: comparative membrane disruption by Cryptdin-4 and its disulfide-null analogue.
    Hadjicharalambous C; Sheynis T; Jelinek R; Shanahan MT; Ouellette AJ; Gizeli E
    Biochemistry; 2008 Nov; 47(47):12626-34. PubMed ID: 18973303
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potent bactericidal activity of reduced cryptdin-4 derived from its hydrophobicity and mediated by bacterial membrane disruption.
    Sato Y; Wang Y; Song Y; Geng W; Yan S; Nakamura K; Kikukawa T; Demura M; Ayabe T; Aizawa T
    Amino Acids; 2022 Feb; 54(2):289-297. PubMed ID: 35037097
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alternative luminal activation mechanisms for paneth cell α-defensins.
    Mastroianni JR; Costales JK; Zaksheske J; Selsted ME; Salzman NH; Ouellette AJ
    J Biol Chem; 2012 Mar; 287(14):11205-12. PubMed ID: 22334698
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Arginine in α-defensins: differential effects on bactericidal activity correspond to geometry of membrane curvature generation and peptide-lipid phase behavior.
    Schmidt NW; Tai KP; Kamdar K; Mishra A; Lai GH; Zhao K; Ouellette AJ; Wong GC
    J Biol Chem; 2012 Jun; 287(26):21866-72. PubMed ID: 22566697
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Efficient production of a correctly folded mouse α-defensin, cryptdin-4, by refolding during inclusion body solubilization.
    Tomisawa S; Sato Y; Kamiya M; Kumaki Y; Kikukawa T; Kawano K; Demura M; Nakamura K; Ayabe T; Aizawa T
    Protein Expr Purif; 2015 Aug; 112():21-8. PubMed ID: 25913370
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.