285 related articles for article (PubMed ID: 22289650)
1. The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model.
Ezzatizadeh V; Pinto RM; Sandi C; Sandi M; Al-Mahdawi S; Te Riele H; Pook MA
Neurobiol Dis; 2012 Apr; 46(1):165-71. PubMed ID: 22289650
[TBL] [Abstract][Full Text] [Related]
2. MutLα heterodimers modify the molecular phenotype of Friedreich ataxia.
Ezzatizadeh V; Sandi C; Sandi M; Anjomani-Virmouni S; Al-Mahdawi S; Pook MA
PLoS One; 2014; 9(6):e100523. PubMed ID: 24971578
[TBL] [Abstract][Full Text] [Related]
3. Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues.
Bourn RL; De Biase I; Pinto RM; Sandi C; Al-Mahdawi S; Pook MA; Bidichandani SI
PLoS One; 2012; 7(10):e47085. PubMed ID: 23071719
[TBL] [Abstract][Full Text] [Related]
4. MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice.
Tomé S; Holt I; Edelmann W; Morris GE; Munnich A; Pearson CE; Gourdon G
PLoS Genet; 2009 May; 5(5):e1000482. PubMed ID: 19436705
[TBL] [Abstract][Full Text] [Related]
5. DNA mismatch repair complex MutSβ promotes GAA·TTC repeat expansion in human cells.
Halabi A; Ditch S; Wang J; Grabczyk E
J Biol Chem; 2012 Aug; 287(35):29958-67. PubMed ID: 22787155
[TBL] [Abstract][Full Text] [Related]
6. Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells.
Du J; Campau E; Soragni E; Ku S; Puckett JW; Dervan PB; Gottesfeld JM
J Biol Chem; 2012 Aug; 287(35):29861-72. PubMed ID: 22798143
[TBL] [Abstract][Full Text] [Related]
7. Disease-associated repeat instability and mismatch repair.
Schmidt MHM; Pearson CE
DNA Repair (Amst); 2016 Feb; 38():117-126. PubMed ID: 26774442
[TBL] [Abstract][Full Text] [Related]
8. GAA repeat instability in Friedreich ataxia YAC transgenic mice.
Al-Mahdawi S; Pinto RM; Ruddle P; Carroll C; Webster Z; Pook M
Genomics; 2004 Aug; 84(2):301-10. PubMed ID: 15233994
[TBL] [Abstract][Full Text] [Related]
9. GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology.
Al-Mahdawi S; Pinto RM; Varshney D; Lawrence L; Lowrie MB; Hughes S; Webster Z; Blake J; Cooper JM; King R; Pook MA
Genomics; 2006 Nov; 88(5):580-90. PubMed ID: 16919418
[TBL] [Abstract][Full Text] [Related]
10. Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6.
Hegan DC; Narayanan L; Jirik FR; Edelmann W; Liskay RM; Glazer PM
Carcinogenesis; 2006 Dec; 27(12):2402-8. PubMed ID: 16728433
[TBL] [Abstract][Full Text] [Related]
11. A novel GAA-repeat-expansion-based mouse model of Friedreich's ataxia.
Anjomani Virmouni S; Ezzatizadeh V; Sandi C; Sandi M; Al-Mahdawi S; Chutake Y; Pook MA
Dis Model Mech; 2015 Mar; 8(3):225-35. PubMed ID: 25681319
[TBL] [Abstract][Full Text] [Related]
12. Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice.
Foiry L; Dong L; Savouret C; Hubert L; te Riele H; Junien C; Gourdon G
Hum Genet; 2006 Jun; 119(5):520-6. PubMed ID: 16552576
[TBL] [Abstract][Full Text] [Related]
13. Base excision repair of chemotherapeutically-induced alkylated DNA damage predominantly causes contractions of expanded GAA repeats associated with Friedreich's ataxia.
Lai Y; Beaver JM; Lorente K; Melo J; Ramjagsingh S; Agoulnik IU; Zhang Z; Liu Y
PLoS One; 2014; 9(4):e93464. PubMed ID: 24691413
[TBL] [Abstract][Full Text] [Related]
14. The GAA triplet-repeat is unstable in the context of the human FXN locus and displays age-dependent expansions in cerebellum and DRG in a transgenic mouse model.
Clark RM; De Biase I; Malykhina AP; Al-Mahdawi S; Pook M; Bidichandani SI
Hum Genet; 2007 Jan; 120(5):633-40. PubMed ID: 17024371
[TBL] [Abstract][Full Text] [Related]
15. Somatic instability of the expanded GAA repeats in Friedreich's ataxia.
Long A; Napierala JS; Polak U; Hauser L; Koeppen AH; Lynch DR; Napierala M
PLoS One; 2017; 12(12):e0189990. PubMed ID: 29261783
[TBL] [Abstract][Full Text] [Related]
16. E. coli mismatch repair acts downstream of replication fork stalling to stabilize the expanded (GAA.TTC)(n) sequence.
Bourn RL; Rindler PM; Pollard LM; Bidichandani SI
Mutat Res; 2009 Feb; 661(1-2):71-7. PubMed ID: 19046977
[TBL] [Abstract][Full Text] [Related]
17. MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions.
Keogh N; Chan KY; Li GM; Lahue RS
Nucleic Acids Res; 2017 Sep; 45(17):10068-10078. PubMed ID: 28973443
[TBL] [Abstract][Full Text] [Related]
18. Cellular, molecular and functional characterisation of YAC transgenic mouse models of Friedreich ataxia.
Anjomani Virmouni S; Sandi C; Al-Mahdawi S; Pook MA
PLoS One; 2014; 9(9):e107416. PubMed ID: 25198290
[TBL] [Abstract][Full Text] [Related]
19. Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks.
Slean MM; Panigrahi GB; Castel AL; Pearson AB; Tomkinson AE; Pearson CE
DNA Repair (Amst); 2016 Jun; 42():107-18. PubMed ID: 27155933
[TBL] [Abstract][Full Text] [Related]
20. Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes.
Dragileva E; Hendricks A; Teed A; Gillis T; Lopez ET; Friedberg EC; Kucherlapati R; Edelmann W; Lunetta KL; MacDonald ME; Wheeler VC
Neurobiol Dis; 2009 Jan; 33(1):37-47. PubMed ID: 18930147
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
