These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
226 related articles for article (PubMed ID: 22300096)
1. Accelerating cocaine metabolism as an approach to the treatment of cocaine abuse and toxicity. Schindler CW; Goldberg SR Future Med Chem; 2012 Feb; 4(2):163-75. PubMed ID: 22300096 [TBL] [Abstract][Full Text] [Related]
2. Bacterial cocaine esterase: a protein-based therapy for cocaine overdose and addiction. Narasimhan D; Woods JH; Sunahara RK Future Med Chem; 2012 Feb; 4(2):137-50. PubMed ID: 22300094 [TBL] [Abstract][Full Text] [Related]
3. Recent progress in protein drug design and discovery with a focus on novel approaches to the development of anti-cocaine medications. Zheng F; Zhan CG Future Med Chem; 2009 Jun; 1(3):515-28. PubMed ID: 20161378 [TBL] [Abstract][Full Text] [Related]
4. Development of a Highly Efficient Long-Acting Cocaine Hydrolase Entity to Accelerate Cocaine Metabolism. Zheng F; Jin Z; Deng J; Chen X; Zheng X; Wang G; Kim K; Shang L; Zhou Z; Zhan CG Bioconjug Chem; 2022 Jul; 33(7):1340-1349. PubMed ID: 35767675 [TBL] [Abstract][Full Text] [Related]
5. Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase. Cooper ZD; Narasimhan D; Sunahara RK; Mierzejewski P; Jutkiewicz EM; Larsen NA; Wilson IA; Landry DW; Woods JH Mol Pharmacol; 2006 Dec; 70(6):1885-91. PubMed ID: 16968810 [TBL] [Abstract][Full Text] [Related]
6. Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine. Xue L; Hou S; Tong M; Fang L; Chen X; Jin Z; Tai HH; Zheng F; Zhan CG Biochem J; 2013 Aug; 453(3):447-54. PubMed ID: 23849058 [TBL] [Abstract][Full Text] [Related]
7. Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene. Zheng X; Chen X; Zhang T; Zhan M; Zhan CG; Zheng F Org Biomol Chem; 2020 Mar; 18(10):1968-1977. PubMed ID: 32101217 [TBL] [Abstract][Full Text] [Related]
8. Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity. Larrimore KE; Barcus M; Kannan L; Gao Y; Zhan CG; Brimijoin S; Mor T Chem Biol Interact; 2013 Mar; 203(1):217-20. PubMed ID: 23000451 [TBL] [Abstract][Full Text] [Related]
9. Anti-cocaine antibody and butyrylcholinesterase-derived cocaine hydrolase exert cooperative effects on cocaine pharmacokinetics and cocaine-induced locomotor activity in mice. Brimijoin S; Orson F; Kosten TR; Kinsey B; Shen XY; White SJ; Gao Y Chem Biol Interact; 2013 Mar; 203(1):212-6. PubMed ID: 22960160 [TBL] [Abstract][Full Text] [Related]
10. The Rhodococcus sp. cocaine esterase: a bacterial candidate for novel pharmacokinetic-based therapies for cocaine abuse. Ascenzi P; Clementi E; Polticelli F IUBMB Life; 2003 Jul; 55(7):397-402. PubMed ID: 14584590 [TBL] [Abstract][Full Text] [Related]
11. Rational design of an enzyme mutant for anti-cocaine therapeutics. Zheng F; Zhan CG J Comput Aided Mol Des; 2008 Sep; 22(9):661-71. PubMed ID: 17989928 [TBL] [Abstract][Full Text] [Related]
13. Catalytic activities of a cocaine hydrolase engineered from human butyrylcholinesterase against (+)- and (-)-cocaine. Xue L; Hou S; Yang W; Fang L; Zheng F; Zhan CG Chem Biol Interact; 2013 Mar; 203(1):57-62. PubMed ID: 22917637 [TBL] [Abstract][Full Text] [Related]
14. Enhancing cocaine metabolism with butyrylcholinesterase as a treatment strategy. Gorelick DA Drug Alcohol Depend; 1997 Dec; 48(3):159-65. PubMed ID: 9449014 [TBL] [Abstract][Full Text] [Related]
15. Physiologic and metabolic safety of butyrylcholinesterase gene therapy in mice. Murthy V; Gao Y; Geng L; LeBrasseur NK; White TA; Parks RJ; Brimijoin S Vaccine; 2014 Jul; 32(33):4155-62. PubMed ID: 24892251 [TBL] [Abstract][Full Text] [Related]
16. Visualizing viral transduction of a cocaine-hydrolyzing, human butyrylcholinesterase in rats. Gao Y; Brimijoin S Chem Biol Interact; 2005 Dec; 157-158():97-103. PubMed ID: 16243302 [TBL] [Abstract][Full Text] [Related]
17. Effects of a cocaine hydrolase engineered from human butyrylcholinesterase on metabolic profile of cocaine in rats. Chen X; Zheng X; Zhou Z; Zhan CG; Zheng F Chem Biol Interact; 2016 Nov; 259(Pt B):104-109. PubMed ID: 27154495 [TBL] [Abstract][Full Text] [Related]
18. Structural analysis of thermostabilizing mutations of cocaine esterase. Narasimhan D; Nance MR; Gao D; Ko MC; Macdonald J; Tamburi P; Yoon D; Landry DM; Woods JH; Zhan CG; Tesmer JJ; Sunahara RK Protein Eng Des Sel; 2010 Jul; 23(7):537-47. PubMed ID: 20436035 [TBL] [Abstract][Full Text] [Related]