204 related articles for article (PubMed ID: 22303960)
21. CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-site APP cleaving protein 1 (BACE1).
Zhao Y; Wang Y; Hu J; Zhang X; Zhang YW
J Biol Chem; 2012 Mar; 287(14):11141-50. PubMed ID: 22351782
[TBL] [Abstract][Full Text] [Related]
22. A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels.
Espeseth AS; Huang Q; Gates A; Xu M; Yu Y; Simon AJ; Shi XP; Zhang X; Hodor P; Stone DJ; Burchard J; Cavet G; Bartz S; Linsley P; Ray WJ; Hazuda D
Mol Cell Neurosci; 2006 Nov; 33(3):227-35. PubMed ID: 16978875
[TBL] [Abstract][Full Text] [Related]
23. Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.
Dorresteijn B; Rotman M; Faber D; Schravesande R; Suidgeest E; van der Weerd L; van der Maarel SM; Verrips CT; El Khattabi M
FEBS J; 2015 Sep; 282(18):3618-31. PubMed ID: 26147692
[TBL] [Abstract][Full Text] [Related]
24. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ
J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
[TBL] [Abstract][Full Text] [Related]
25. CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase.
Singh AK; Pati U
Aging Cell; 2015 Aug; 14(4):595-604. PubMed ID: 25773675
[TBL] [Abstract][Full Text] [Related]
26. Altered amyloid-beta metabolism and deposition in genomic-based beta-secretase transgenic mice.
Chiocco MJ; Kulnane LS; Younkin L; Younkin S; Evin G; Lamb BT
J Biol Chem; 2004 Dec; 279(50):52535-42. PubMed ID: 15452128
[TBL] [Abstract][Full Text] [Related]
27. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
Vassar R
J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789
[TBL] [Abstract][Full Text] [Related]
28. BACE1: the beta-secretase enzyme in Alzheimer's disease.
Vassar R
J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
[TBL] [Abstract][Full Text] [Related]
29. Loss of cleavage at β'-site contributes to apparent increase in β-amyloid peptide (Aβ) secretion by β-secretase (BACE1)-glycosylphosphatidylinositol (GPI) processing of amyloid precursor protein.
Vetrivel KS; Barman A; Chen Y; Nguyen PD; Wagner SL; Prabhakar R; Thinakaran G
J Biol Chem; 2011 Jul; 286(29):26166-77. PubMed ID: 21642424
[TBL] [Abstract][Full Text] [Related]
30. The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.
Stockley JH; O'Neill C
Biochem Soc Trans; 2007 Jun; 35(Pt 3):574-6. PubMed ID: 17511655
[TBL] [Abstract][Full Text] [Related]
31. Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.
Christensen MA; Zhou W; Qing H; Lehman A; Philipsen S; Song W
Mol Cell Biol; 2004 Jan; 24(2):865-74. PubMed ID: 14701757
[TBL] [Abstract][Full Text] [Related]
32. BAG-1M co-activates BACE1 transcription through NF-κB and accelerates Aβ production and memory deficit in Alzheimer's disease mouse model.
Shi Z; Hong Y; Zhang K; Wang J; Zheng L; Zhang Z; Hu Z; Han X; Han Y; Chen T; Yao Q; Cui H; Hong W
Biochim Biophys Acta Mol Basis Dis; 2017 Sep; 1863(9):2398-2407. PubMed ID: 28502705
[TBL] [Abstract][Full Text] [Related]
33. miR-186 is decreased in aged brain and suppresses BACE1 expression.
Kim J; Yoon H; Chung DE; Brown JL; Belmonte KC; Kim J
J Neurochem; 2016 May; 137(3):436-45. PubMed ID: 26710318
[TBL] [Abstract][Full Text] [Related]
34. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
[TBL] [Abstract][Full Text] [Related]
35. The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing.
Rabe S; Reichwald J; Ammaturo D; de Strooper B; Saftig P; Neumann U; Staufenbiel M
J Neurochem; 2011 Oct; 119(1):231-9. PubMed ID: 21812781
[TBL] [Abstract][Full Text] [Related]
36. Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.
Zhang M; Deng Y; Luo Y; Zhang S; Zou H; Cai F; Wada K; Song W
J Neurochem; 2012 Mar; 120(6):1129-38. PubMed ID: 22212137
[TBL] [Abstract][Full Text] [Related]
37. PAR-4 is involved in regulation of beta-secretase cleavage of the Alzheimer amyloid precursor protein.
Xie J; Guo Q
J Biol Chem; 2005 Apr; 280(14):13824-32. PubMed ID: 15671026
[TBL] [Abstract][Full Text] [Related]
38. P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.
Meredith JE; Thompson LA; Toyn JH; Marcin L; Barten DM; Marcinkeviciene J; Kopcho L; Kim Y; Lin A; Guss V; Burton C; Iben L; Polson C; Cantone J; Ford M; Drexler D; Fiedler T; Lentz KA; Grace JE; Kolb J; Corsa J; Pierdomenico M; Jones K; Olson RE; Macor JE; Albright CF
J Pharmacol Exp Ther; 2008 Aug; 326(2):502-13. PubMed ID: 18499745
[TBL] [Abstract][Full Text] [Related]
39. Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells.
Basi G; Frigon N; Barbour R; Doan T; Gordon G; McConlogue L; Sinha S; Zeller M
J Biol Chem; 2003 Aug; 278(34):31512-20. PubMed ID: 12801932
[TBL] [Abstract][Full Text] [Related]
40. Targeting pre-mRNA splicing: a BACE-ic strategy for AD drug development?
Small DH; Aguilar MI
J Neurochem; 2012 Jun; 121(5):695-6. PubMed ID: 22303926
[No Abstract] [Full Text] [Related]
[Previous] [Next] [New Search]