BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 22305267)

  • 21. Geminin overexpression prevents the completion of topoisomerase IIα chromosome decatenation, leading to aneuploidy in human mammary epithelial cells.
    Gardner L; Malik R; Shimizu Y; Mullins N; ElShamy WM
    Breast Cancer Res; 2011 May; 13(3):R53. PubMed ID: 21595939
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Suppression of centrosome protein TACC3 induces G1 arrest and cell death through activation of p38-p53-p21 stress signaling pathway.
    Suhail TV; Singh P; Manna TK
    Eur J Cell Biol; 2015 Feb; 94(2):90-100. PubMed ID: 25613365
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM.
    Engeland K
    Cell Death Differ; 2018 Jan; 25(1):114-132. PubMed ID: 29125603
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.
    Javelaud D; Besancon F
    J Biol Chem; 2002 Oct; 277(40):37949-54. PubMed ID: 12151395
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A Temperature Sensitive Variant of p53 Drives p53-Dependent MicroRNA Expression without Evidence of Widespread Post-Transcriptional Gene Silencing.
    Cabrita MA; Vanzyl EJ; Hamill JD; Pan E; Marcellus KA; Tolls VJ; Alonzi RC; Pastic A; Rambo TM; Sayed H; McKay BC
    PLoS One; 2016; 11(2):e0148529. PubMed ID: 26840126
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Aneuploidy and tumorigenesis.
    Fang X; Zhang P
    Semin Cell Dev Biol; 2011 Aug; 22(6):595-601. PubMed ID: 21392584
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Aneuploidy, the primary cause of the multilateral genomic instability of neoplastic and preneoplastic cells.
    Duesberg P; Fabarius A; Hehlmann R
    IUBMB Life; 2004 Feb; 56(2):65-81. PubMed ID: 15085930
    [TBL] [Abstract][Full Text] [Related]  

  • 28. DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.
    Robert MF; Morin S; Beaulieu N; Gauthier F; Chute IC; Barsalou A; MacLeod AR
    Nat Genet; 2003 Jan; 33(1):61-5. PubMed ID: 12496760
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations.
    Ghadimi BM; Sackett DL; Difilippantonio MJ; Schröck E; Neumann T; Jauho A; Auer G; Ried T
    Genes Chromosomes Cancer; 2000 Feb; 27(2):183-90. PubMed ID: 10612807
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis.
    Dreidax D; Gogolin S; Schroeder C; Muth D; Brueckner LM; Hess EM; Zapatka M; Theißen J; Fischer M; Ehemann V; Schwab M; Savelyeva L; Westermann F
    Hum Mol Genet; 2013 May; 22(9):1735-45. PubMed ID: 23343716
    [TBL] [Abstract][Full Text] [Related]  

  • 31. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.
    Di Leonardo A; Linke SP; Clarkin K; Wahl GM
    Genes Dev; 1994 Nov; 8(21):2540-51. PubMed ID: 7958916
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Prevention of mammalian DNA reduplication, following the release from the mitotic spindle checkpoint, requires p53 protein, but not p53-mediated transcriptional activity.
    Notterman D; Young S; Wainger B; Levine AJ
    Oncogene; 1998 Nov; 17(21):2743-51. PubMed ID: 9840938
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest.
    Mikule K; Delaval B; Kaldis P; Jurcyzk A; Hergert P; Doxsey S
    Nat Cell Biol; 2007 Feb; 9(2):160-70. PubMed ID: 17330329
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis.
    Hemmati PG; Gillissen B; von Haefen C; Wendt J; Stärck L; Güner D; Dörken B; Daniel PT
    Oncogene; 2002 May; 21(20):3149-61. PubMed ID: 12082630
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition.
    Arima Y; Hirota T; Bronner C; Mousli M; Fujiwara T; Niwa S; Ishikawa H; Saya H
    Genes Cells; 2004 Feb; 9(2):131-42. PubMed ID: 15009091
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Defective control of mitotic and post-mitotic checkpoints in poly(ADP-ribose) polymerase-1(-/-) fibroblasts after mitotic spindle disruption.
    Halappanavar SS; Shah GM
    Cell Cycle; 2004 Mar; 3(3):335-42. PubMed ID: 14726664
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Persistent increase in chromosome instability in lung cancer: possible indirect involvement of p53 inactivation.
    Haruki N; Harano T; Masuda A; Kiyono T; Takahashi T; Tatematsu Y; Shimizu S; Mitsudomi T; Konishi H; Osada H; Fujii Y; Takahashi T
    Am J Pathol; 2001 Oct; 159(4):1345-52. PubMed ID: 11583962
    [TBL] [Abstract][Full Text] [Related]  

  • 38. hBub1 deficiency triggers a novel p53 mediated early apoptotic checkpoint pathway in mitotic spindle damaged cells.
    Gao F; Ponte JF; Papageorgis P; Levy M; Ozturk S; Lambert AW; Pan H; Chinnappan D; Cheng KH; Thiagalingam A; Abdolmaleky HM; Thiagalingam S
    Cancer Biol Ther; 2009 Apr; 8(7):627-35. PubMed ID: 19242126
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
    Stott FJ; Bates S; James MC; McConnell BB; Starborg M; Brookes S; Palmero I; Ryan K; Hara E; Vousden KH; Peters G
    EMBO J; 1998 Sep; 17(17):5001-14. PubMed ID: 9724636
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Stranglehold on the spindle assembly checkpoint: the human papillomavirus E2 protein provokes BUBR1-dependent aneuploidy.
    Tan CL; Teissier S; Gunaratne J; Quek LS; Bellanger S
    Cell Cycle; 2015; 14(9):1459-70. PubMed ID: 25789401
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.