360 related articles for article (PubMed ID: 22309842)
1. Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.
Groth C; Fortini ME
Semin Cell Dev Biol; 2012 Jun; 23(4):465-72. PubMed ID: 22309842
[TBL] [Abstract][Full Text] [Related]
2. Small molecules that inhibit Notch signaling.
De Kloe GE; De Strooper B
Methods Mol Biol; 2014; 1187():311-22. PubMed ID: 25053499
[TBL] [Abstract][Full Text] [Related]
3. Notch Signaling: A Potential Therapeutic Target for Hematologic Malignancies.
Gao L; Yuan K; Ding W; Lin M
Crit Rev Eukaryot Gene Expr; 2016; 26(3):239-46. PubMed ID: 27650987
[TBL] [Abstract][Full Text] [Related]
4. Mechanisms and clinical prospects of Notch inhibitors in the therapy of hematological malignancies.
Nefedova Y; Gabrilovich D
Drug Resist Updat; 2008 Dec; 11(6):210-8. PubMed ID: 18951834
[TBL] [Abstract][Full Text] [Related]
5. Notch Signalling Pathways and Their Importance in the Treatment of Cancers.
Teoh SL; Das S
Curr Drug Targets; 2018; 19(2):128-143. PubMed ID: 28294046
[TBL] [Abstract][Full Text] [Related]
6. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
Hales EC; Taub JW; Matherly LH
Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
[TBL] [Abstract][Full Text] [Related]
7. NOTCH signaling as a novel cancer therapeutic target.
Miele L; Miao H; Nickoloff BJ
Curr Cancer Drug Targets; 2006 Jun; 6(4):313-23. PubMed ID: 16848722
[TBL] [Abstract][Full Text] [Related]
8. Rethinking Gamma-secretase Inhibitors for Treatment of Non-small-Cell Lung Cancer: Is Notch the Target?
Pine SR
Clin Cancer Res; 2018 Dec; 24(24):6136-6141. PubMed ID: 30104200
[TBL] [Abstract][Full Text] [Related]
9. [Inhibitors for Notch and gamma-secretase. Biology of T-cell leukemia].
Yahagi Y; Usui N
Gan To Kagaku Ryoho; 2009 May; 36(5):744-8. PubMed ID: 19496283
[No Abstract] [Full Text] [Related]
10. Blocking the NOTCH pathway can inhibit the growth of CD133-positive A549 cells and sensitize to chemotherapy.
Liu J; Mao Z; Huang J; Xie S; Liu T; Mao Z
Biochem Biophys Res Commun; 2014 Feb; 444(4):670-5. PubMed ID: 24502949
[TBL] [Abstract][Full Text] [Related]
11. Notch Signaling in Breast Cancer: A Role in Drug Resistance.
BeLow M; Osipo C
Cells; 2020 Sep; 9(10):. PubMed ID: 33003540
[TBL] [Abstract][Full Text] [Related]
12. Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.
Konishi J; Kawaguchi KS; Vo H; Haruki N; Gonzalez A; Carbone DP; Dang TP
Cancer Res; 2007 Sep; 67(17):8051-7. PubMed ID: 17804716
[TBL] [Abstract][Full Text] [Related]
13. Evaluation of selective gamma-secretase inhibitor PF-03084014 for its antitumor efficacy and gastrointestinal safety to guide optimal clinical trial design.
Wei P; Walls M; Qiu M; Ding R; Denlinger RH; Wong A; Tsaparikos K; Jani JP; Hosea N; Sands M; Randolph S; Smeal T
Mol Cancer Ther; 2010 Jun; 9(6):1618-28. PubMed ID: 20530712
[TBL] [Abstract][Full Text] [Related]
14. Notch Antagonists: Potential Modulators of Cancer and Inflammatory Diseases.
Kumar R; Juillerat-Jeanneret L; Golshayan D
J Med Chem; 2016 Sep; 59(17):7719-37. PubMed ID: 27045975
[TBL] [Abstract][Full Text] [Related]
15. Notch signaling in breast cancer and tumor angiogenesis: cross-talk and therapeutic potentials.
Shi W; Harris AL
J Mammary Gland Biol Neoplasia; 2006 Jan; 11(1):41-52. PubMed ID: 16947085
[TBL] [Abstract][Full Text] [Related]
16. Mesoporous silica nanoparticles as drug delivery systems for targeted inhibition of Notch signaling in cancer.
Mamaeva V; Rosenholm JM; Bate-Eya LT; Bergman L; Peuhu E; Duchanoy A; Fortelius LE; Landor S; Toivola DM; Lindén M; Sahlgren C
Mol Ther; 2011 Aug; 19(8):1538-46. PubMed ID: 21629222
[TBL] [Abstract][Full Text] [Related]
17. Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein.
Yang T; Arslanova D; Gu Y; Augelli-Szafran C; Xia W
Mol Brain; 2008 Nov; 1():15. PubMed ID: 18983676
[TBL] [Abstract][Full Text] [Related]
18. Rational targeting of Notch signaling in cancer.
Rizzo P; Osipo C; Foreman K; Golde T; Osborne B; Miele L
Oncogene; 2008 Sep; 27(38):5124-31. PubMed ID: 18758481
[TBL] [Abstract][Full Text] [Related]
19. Precision medicine for human cancers with Notch signaling dysregulation (Review).
Katoh M; Katoh M
Int J Mol Med; 2020 Feb; 45(2):279-297. PubMed ID: 31894255
[TBL] [Abstract][Full Text] [Related]
20. Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation.
Vo K; Amarasinghe B; Washington K; Gonzalez A; Berlin J; Dang TP
Mol Cancer; 2011 Nov; 10():138. PubMed ID: 22074495
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
