BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 22309894)

  • 1. LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses.
    Tokunaga F; Iwai K
    Microbes Infect; 2012 Jul; 14(7-8):563-72. PubMed ID: 22309894
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Linear ubiquitination-mediated NF-κB regulation and its related disorders.
    Tokunaga F
    J Biochem; 2013 Oct; 154(4):313-23. PubMed ID: 23969028
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Linear ubiquitination: a novel NF-κB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex.
    Tokunaga F; Iwai K
    Endocr J; 2012; 59(8):641-52. PubMed ID: 22673407
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Porcine Reproductive and Respiratory Syndrome Virus nsp1α Inhibits NF-κB Activation by Targeting the Linear Ubiquitin Chain Assembly Complex.
    Jing H; Fang L; Ding Z; Wang D; Hao W; Gao L; Ke W; Chen H; Xiao S
    J Virol; 2017 Feb; 91(3):. PubMed ID: 27881655
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling.
    Katsuya K; Oikawa D; Iio K; Obika S; Hori Y; Urashima T; Ayukawa K; Tokunaga F
    Biochem Biophys Res Commun; 2019 Feb; 509(3):700-706. PubMed ID: 30611571
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain Formation.
    Bowman J; Rodgers MA; Shi M; Amatya R; Hostager B; Iwai K; Gao SJ; Jung JU
    mBio; 2015 Nov; 6(6):e01777-15. PubMed ID: 26578682
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation.
    Rodgers MA; Bowman JW; Fujita H; Orazio N; Shi M; Liang Q; Amatya R; Kelly TJ; Iwai K; Ting J; Jung JU
    J Exp Med; 2014 Jun; 211(7):1333-47. PubMed ID: 24958845
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system.
    Sasaki K; Iwai K
    Immunol Rev; 2015 Jul; 266(1):175-89. PubMed ID: 26085215
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC.
    Fuseya Y; Fujita H; Kim M; Ohtake F; Nishide A; Sasaki K; Saeki Y; Tanaka K; Takahashi R; Iwai K
    Nat Cell Biol; 2020 Jun; 22(6):663-673. PubMed ID: 32393887
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biochemistry, Pathophysiology, and Regulation of Linear Ubiquitination: Intricate Regulation by Coordinated Functions of the Associated Ligase and Deubiquitinase.
    Fuseya Y; Iwai K
    Cells; 2021 Oct; 10(10):. PubMed ID: 34685685
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gliotoxin suppresses NF-κB activation by selectively inhibiting linear ubiquitin chain assembly complex (LUBAC).
    Sakamoto H; Egashira S; Saito N; Kirisako T; Miller S; Sasaki Y; Matsumoto T; Shimonishi M; Komatsu T; Terai T; Ueno T; Hanaoka K; Kojima H; Okabe T; Wakatsuki S; Iwai K; Nagano T
    ACS Chem Biol; 2015 Mar; 10(3):675-81. PubMed ID: 25494483
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IFN-γ or IFN-α ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex.
    Tamiya H; Terao M; Takiuchi T; Nakahara M; Sasaki Y; Katayama I; Yoshikawa H; Iwai K
    J Immunol; 2014 Apr; 192(8):3793-804. PubMed ID: 24634492
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis.
    Ikeda F; Deribe YL; Skånland SS; Stieglitz B; Grabbe C; Franz-Wachtel M; van Wijk SJ; Goswami P; Nagy V; Terzic J; Tokunaga F; Androulidaki A; Nakagawa T; Pasparakis M; Iwai K; Sundberg JP; Schaefer L; Rittinger K; Macek B; Dikic I
    Nature; 2011 Mar; 471(7340):637-41. PubMed ID: 21455181
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Linear Ubiquitin Code: Its Writer, Erasers, Decoders, Inhibitors, and Implications in Disorders.
    Oikawa D; Sato Y; Ito H; Tokunaga F
    Int J Mol Sci; 2020 May; 21(9):. PubMed ID: 32403254
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MALT1 cleaves the E3 ubiquitin ligase HOIL-1 in activated T cells, generating a dominant negative inhibitor of LUBAC-induced NF-κB signaling.
    Elton L; Carpentier I; Staal J; Driege Y; Haegman M; Beyaert R
    FEBS J; 2016 Feb; 283(3):403-12. PubMed ID: 26573773
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex.
    Tokunaga F; Nakagawa T; Nakahara M; Saeki Y; Taniguchi M; Sakata S; Tanaka K; Nakano H; Iwai K
    Nature; 2011 Mar; 471(7340):633-6. PubMed ID: 21455180
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Decreased linear ubiquitination of NEMO and FADD on apoptosis with caspase-mediated cleavage of HOIP.
    Goto E; Tokunaga F
    Biochem Biophys Res Commun; 2017 Mar; 485(1):152-159. PubMed ID: 28189684
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Attenuation of HOIL-1L ligase activity promotes systemic autoimmune disorders by augmenting linear ubiquitin signaling.
    Fuseya Y; Kadoba K; Liu X; Suetsugu H; Iwasaki T; Ohmura K; Sumida T; Kochi Y; Morinobu A; Terao C; Iwai K
    JCI Insight; 2024 Feb; 9(3):. PubMed ID: 38329126
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of
    Liu J; Wang Y; Wang D; Wang Y; Xu X; Zhang Y; Li Y; Zhang M; Gong X; Tang Y; Shen L; Li M; Pan L
    Proc Natl Acad Sci U S A; 2022 Mar; 119(12):e2116776119. PubMed ID: 35294289
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biophysical and biological evaluation of optimized stapled peptide inhibitors of the linear ubiquitin chain assembly complex (LUBAC).
    Aguilar-Alonso F; Whiting AL; Kim YJ; Bernal F
    Bioorg Med Chem; 2018 Mar; 26(6):1179-1188. PubMed ID: 29246782
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.