BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

293 related articles for article (PubMed ID: 22311977)

  • 1. Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels.
    Shilling D; Mak DO; Kang DE; Foskett JK
    J Biol Chem; 2012 Mar; 287(14):10933-44. PubMed ID: 22311977
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
    Zatti G; Burgo A; Giacomello M; Barbiero L; Ghidoni R; Sinigaglia G; Florean C; Bagnoli S; Binetti G; Sorbi S; Pizzo P; Fasolato C
    Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.
    Tu H; Nelson O; Bezprozvanny A; Wang Z; Lee SF; Hao YH; Serneels L; De Strooper B; Yu G; Bezprozvanny I
    Cell; 2006 Sep; 126(5):981-93. PubMed ID: 16959576
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1.
    Nelson O; Tu H; Lei T; Bentahir M; de Strooper B; Bezprozvanny I
    J Clin Invest; 2007 May; 117(5):1230-9. PubMed ID: 17431506
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Familial Alzheimer's disease-linked presenilin mutants and intracellular Ca
    Greotti E; Capitanio P; Wong A; Pozzan T; Pizzo P; Pendin D
    Cell Calcium; 2019 May; 79():44-56. PubMed ID: 30822648
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons.
    Cheung KH; Mei L; Mak DO; Hayashi I; Iwatsubo T; Kang DE; Foskett JK
    Sci Signal; 2010 Mar; 3(114):ra22. PubMed ID: 20332427
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.
    Wu B; Yamaguchi H; Lai FA; Shen J
    Proc Natl Acad Sci U S A; 2013 Sep; 110(37):15091-6. PubMed ID: 23918386
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.
    Das HK; Tchedre K; Mueller B
    J Neurochem; 2012 Aug; 122(3):487-500. PubMed ID: 22607268
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Familial Alzheimer's disease mutations in presenilins: effects on endoplasmic reticulum calcium homeostasis and correlation with clinical phenotypes.
    Nelson O; Supnet C; Liu H; Bezprozvanny I
    J Alzheimers Dis; 2010; 21(3):781-93. PubMed ID: 20634584
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling.
    Müller M; Cárdenas C; Mei L; Cheung KH; Foskett JK
    Proc Natl Acad Sci U S A; 2011 Aug; 108(32):13293-8. PubMed ID: 21784978
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced ROS generation mediated by Alzheimer's disease presenilin regulation of InsP3R Ca2+ signaling.
    Müller M; Cheung KH; Foskett JK
    Antioxid Redox Signal; 2011 Apr; 14(7):1225-35. PubMed ID: 20701429
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of presenilins in neuronal calcium homeostasis.
    Zhang H; Sun S; Herreman A; De Strooper B; Bezprozvanny I
    J Neurosci; 2010 Jun; 30(25):8566-80. PubMed ID: 20573903
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis.
    Supnet C; Bezprozvanny I
    Sci China Life Sci; 2011 Aug; 54(8):744-51. PubMed ID: 21786197
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PSEN2 (presenilin 2) mutants linked to familial Alzheimer disease impair autophagy by altering Ca
    Fedeli C; Filadi R; Rossi A; Mammucari C; Pizzo P
    Autophagy; 2019 Dec; 15(12):2044-2062. PubMed ID: 30892128
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A comprehensive overview of the complex world of the endo- and sarcoplasmic reticulum Ca
    Lemos FO; Bultynck G; Parys JB
    Biochim Biophys Acta Mol Cell Res; 2021 Jun; 1868(7):119020. PubMed ID: 33798602
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production.
    Green KN; Demuro A; Akbari Y; Hitt BD; Smith IF; Parker I; LaFerla FM
    J Cell Biol; 2008 Jun; 181(7):1107-16. PubMed ID: 18591429
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Up-regulation of inositol 1,4,5-trisphosphate receptor type 1 is responsible for a decreased endoplasmic-reticulum Ca2+ content in presenilin double knock-out cells.
    Kasri NN; Kocks SL; Verbert L; Hébert SS; Callewaert G; Parys JB; Missiaen L; De Smedt H
    Cell Calcium; 2006 Jul; 40(1):41-51. PubMed ID: 16675011
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease.
    Honarnejad K; Daschner A; Giese A; Zall A; Schmidt B; Szybinska A; Kuznicki J; Herms J
    PLoS One; 2013; 8(11):e80645. PubMed ID: 24260442
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.
    Shilling D; Müller M; Takano H; Mak DO; Abel T; Coulter DA; Foskett JK
    J Neurosci; 2014 May; 34(20):6910-23. PubMed ID: 24828645
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Presenilins function in ER calcium leak and Alzheimer's disease pathogenesis.
    Supnet C; Bezprozvanny I
    Cell Calcium; 2011 Sep; 50(3):303-9. PubMed ID: 21663966
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.