Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

641 related articles for article (PubMed ID: 22313602)

  • 1. Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.
    Witkiewicz AK; Whitaker-Menezes D; Dasgupta A; Philp NJ; Lin Z; Gandara R; Sneddon S; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Mar; 11(6):1108-17. PubMed ID: 22313602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer.
    Curry JM; Tuluc M; Whitaker-Menezes D; Ames JA; Anantharaman A; Butera A; Leiby B; Cognetti DM; Sotgia F; Lisanti MP; Martinez-Outschoorn UE
    Cell Cycle; 2013 May; 12(9):1371-84. PubMed ID: 23574725
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.
    Whitaker-Menezes D; Martinez-Outschoorn UE; Lin Z; Ertel A; Flomenberg N; Witkiewicz AK; Birbe RC; Howell A; Pavlides S; Gandara R; Pestell RG; Sotgia F; Philp NJ; Lisanti MP
    Cell Cycle; 2011 Jun; 10(11):1772-83. PubMed ID: 21558814
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.
    Sotgia F; Whitaker-Menezes D; Martinez-Outschoorn UE; Flomenberg N; Birbe RC; Witkiewicz AK; Howell A; Philp NJ; Pestell RG; Lisanti MP
    Cell Cycle; 2012 Apr; 11(7):1445-54. PubMed ID: 22395432
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function.
    Martinez-Outschoorn U; Sotgia F; Lisanti MP
    Semin Oncol; 2014 Apr; 41(2):195-216. PubMed ID: 24787293
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies.
    Martinez-Outschoorn UE; Balliet R; Lin Z; Whitaker-Menezes D; Birbe RC; Bombonati A; Pavlides S; Lamb R; Sneddon S; Howell A; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Dec; 11(23):4402-13. PubMed ID: 23172369
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma.
    Pavlides S; Whitaker-Menezes D; Castello-Cros R; Flomenberg N; Witkiewicz AK; Frank PG; Casimiro MC; Wang C; Fortina P; Addya S; Pestell RG; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cell Cycle; 2009 Dec; 8(23):3984-4001. PubMed ID: 19923890
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.
    Guido C; Whitaker-Menezes D; Capparelli C; Balliet R; Lin Z; Pestell RG; Howell A; Aquila S; Andò S; Martinez-Outschoorn U; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Aug; 11(16):3019-35. PubMed ID: 22874531
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.
    Martinez-Outschoorn UE; Curry JM; Ko YH; Lin Z; Tuluc M; Cognetti D; Birbe RC; Pribitkin E; Bombonati A; Pestell RG; Howell A; Sotgia F; Lisanti MP
    Cell Cycle; 2013 Aug; 12(16):2580-97. PubMed ID: 23860378
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.
    Chiavarina B; Whitaker-Menezes D; Martinez-Outschoorn UE; Witkiewicz AK; Birbe R; Howell A; Pestell RG; Smith J; Daniel R; Sotgia F; Lisanti MP
    Cancer Biol Ther; 2011 Dec; 12(12):1101-13. PubMed ID: 22236875
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling.
    Migneco G; Whitaker-Menezes D; Chiavarina B; Castello-Cros R; Pavlides S; Pestell RG; Fatatis A; Flomenberg N; Tsirigos A; Howell A; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cell Cycle; 2010 Jun; 9(12):2412-22. PubMed ID: 20562527
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome.
    Doyen J; Trastour C; Ettore F; Peyrottes I; Toussant N; Gal J; Ilc K; Roux D; Parks SK; Ferrero JM; Pouysségur J
    Biochem Biophys Res Commun; 2014 Aug; 451(1):54-61. PubMed ID: 25058459
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection.
    Balliet RM; Capparelli C; Guido C; Pestell TG; Martinez-Outschoorn UE; Lin Z; Whitaker-Menezes D; Chiavarina B; Pestell RG; Howell A; Sotgia F; Lisanti MP
    Cell Cycle; 2011 Dec; 10(23):4065-73. PubMed ID: 22129993
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment.
    Sotgia F; Martinez-Outschoorn UE; Pavlides S; Howell A; Pestell RG; Lisanti MP
    Breast Cancer Res; 2011 Jul; 13(4):213. PubMed ID: 21867571
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic phenotypes in triple-negative breast cancer.
    Kim S; Kim DH; Jung WH; Koo JS
    Tumour Biol; 2013 Jun; 34(3):1699-712. PubMed ID: 23443971
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hodgkin lymphoma: A complex metabolic ecosystem with glycolytic reprogramming of the tumor microenvironment.
    Mikkilineni L; Whitaker-Menezes D; Domingo-Vidal M; Sprandio J; Avena P; Cotzia P; Dulau-Florea A; Gong J; Uppal G; Zhan T; Leiby B; Lin Z; Pro B; Sotgia F; Lisanti MP; Martinez-Outschoorn U
    Semin Oncol; 2017 Jun; 44(3):218-225. PubMed ID: 29248133
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A reverse Warburg metabolism in oral squamous cell carcinoma is not dependent upon myofibroblasts.
    Jensen DH; Therkildsen MH; Dabelsteen E
    J Oral Pathol Med; 2015 Oct; 44(9):714-21. PubMed ID: 25420473
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.
    Whitaker-Menezes D; Martinez-Outschoorn UE; Flomenberg N; Birbe RC; Witkiewicz AK; Howell A; Pavlides S; Tsirigos A; Ertel A; Pestell RG; Broda P; Minetti C; Lisanti MP; Sotgia F
    Cell Cycle; 2011 Dec; 10(23):4047-64. PubMed ID: 22134189
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.
    Martinez-Outschoorn UE; Balliet RM; Rivadeneira DB; Chiavarina B; Pavlides S; Wang C; Whitaker-Menezes D; Daumer KM; Lin Z; Witkiewicz AK; Flomenberg N; Howell A; Pestell RG; Knudsen ES; Sotgia F; Lisanti MP
    Cell Cycle; 2010 Aug; 9(16):3256-76. PubMed ID: 20814239
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells.
    Diehl K; Dinges LA; Helm O; Ammar N; Plundrich D; Arlt A; Röcken C; Sebens S; Schäfer H
    Oncogene; 2018 Jan; 37(1):39-51. PubMed ID: 28846107
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.