These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 22313785)

  • 1. Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
    Hidaka M; Koga T; Kiyota H; Horiguchi T; Shi QW; Hirose K; Uchida T
    Biosci Biotechnol Biochem; 2012; 76(2):349-52. PubMed ID: 22313785
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel taxane derivatives from Taxus wallichiana with high anticancer potency on tumor cells.
    Wang Y; Wang J; Wang H; Ye W
    Chem Biol Drug Des; 2016 Oct; 88(4):556-61. PubMed ID: 27153813
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular mechanism of action of microtubule-stabilizing anticancer agents.
    Prota AE; Bargsten K; Zurwerra D; Field JJ; Díaz JF; Altmann KH; Steinmetz MO
    Science; 2013 Feb; 339(6119):587-90. PubMed ID: 23287720
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro.
    Cai P; Lu P; Sharom FJ; Fang WS
    Cancer Lett; 2013 Dec; 341(2):214-23. PubMed ID: 23941826
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
    Matesanz R; Trigili C; Rodríguez-Salarichs J; Zanardi I; Pera B; Nogales A; Fang WS; Jímenez-Barbero J; Canales A; Barasoain I; Ojima I; Díaz JF
    Bioorg Med Chem; 2014 Sep; 22(18):5078-90. PubMed ID: 25047938
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mobility of nitroxyl-labelled taxol during tubulin assembly.
    Nicholov R; Kingston DG; Chordia MC; DiCosmo F
    FEBS Lett; 1997 Mar; 405(1):73-6. PubMed ID: 9094427
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 3D QSAR models of interactions between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA): a survey on taxanes and epothilones.
    Manetti F; Maccari L; Corelli F; Botta M
    Curr Top Med Chem; 2004; 4(2):203-17. PubMed ID: 14754454
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads.
    Chen QH; Kingston DG
    Nat Prod Rep; 2014 Sep; 31(9):1202-26. PubMed ID: 24945566
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
    Field JJ; Pera B; Calvo E; Canales A; Zurwerra D; Trigili C; Rodríguez-Salarichs J; Matesanz R; Kanakkanthara A; Wakefield SJ; Singh AJ; Jiménez-Barbero J; Northcote P; Miller JH; López JA; Hamel E; Barasoain I; Altmann KH; Díaz JF
    Chem Biol; 2012 Jun; 19(6):686-98. PubMed ID: 22726683
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site.
    Lo YC; Cormier O; Liu T; Nettles KW; Katzenellenbogen JA; Stearns T; Altman RB
    Nat Commun; 2019 Mar; 10(1):1033. PubMed ID: 30833575
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Understanding tubulin/microtubule-taxane interactions: a quantitative structure-activity relationship study.
    Hansch C; Verma RP
    Mol Pharm; 2008; 5(1):151-61. PubMed ID: 18171015
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lx2-32c, a novel taxane and its antitumor activities in vitro and in vivo.
    Wang H; Li H; Zuo M; Zhang Y; Liu H; Fang W; Chen X
    Cancer Lett; 2008 Sep; 268(1):89-97. PubMed ID: 18482796
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Search for new MDR modifier possessing taxane skeleton].
    Kobayashi J
    Nihon Rinsho; 1997 May; 55(5):1135-42. PubMed ID: 9155165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological activities of high affinity taxane-based fluorescent probes.
    Li X; Barasoain I; Matesanz R; Díaz JF; Fang WS
    Bioorg Med Chem Lett; 2009 Feb; 19(3):751-4. PubMed ID: 19128972
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression.
    Heuer TS; Ventura R; Mordec K; Lai J; Fridlib M; Buckley D; Kemble G
    EBioMedicine; 2017 Feb; 16():51-62. PubMed ID: 28159572
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of C7 substitutions in a high affinity microtubule-binding taxane on antitumor activity and drug transport.
    Xiao X; Wu J; Trigili C; Chen H; Chu JW; Zhao Y; Lu P; Sheng L; Li Y; Sharom FJ; Barasoain I; Diaz JF; Fang WS
    Bioorg Med Chem Lett; 2011 Aug; 21(16):4852-6. PubMed ID: 21764308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.
    Kellogg EH; Hejab NMA; Howes S; Northcote P; Miller JH; Díaz JF; Downing KH; Nogales E
    J Mol Biol; 2017 Mar; 429(5):633-646. PubMed ID: 28104363
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stabilization of microtubules by taxane diterpenoids: insight from docking and MD simulations.
    Yadava U; Gupta H; Roychoudhury M
    J Biol Phys; 2015 Mar; 41(2):117-33. PubMed ID: 25542396
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationship of taxol inferring from docking taxol analogues to microtubule binding site.
    Xiang F; Yu J; Yin R; Ma Y; Yu L
    Z Naturforsch C J Biosci; 2009; 64(7-8):551-6. PubMed ID: 19791508
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationships of ring C-secotaxoids. 1. Acylative modifications.
    Appendino G; Bettoni P; Noncovich A; Sterner O; Fontana G; Bombardelli E; Pera P; Bernacki RJ
    J Nat Prod; 2004 Feb; 67(2):184-8. PubMed ID: 14987056
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.