207 related articles for article (PubMed ID: 22313785)
1. Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
Hidaka M; Koga T; Kiyota H; Horiguchi T; Shi QW; Hirose K; Uchida T
Biosci Biotechnol Biochem; 2012; 76(2):349-52. PubMed ID: 22313785
[TBL] [Abstract][Full Text] [Related]
2. Novel taxane derivatives from Taxus wallichiana with high anticancer potency on tumor cells.
Wang Y; Wang J; Wang H; Ye W
Chem Biol Drug Des; 2016 Oct; 88(4):556-61. PubMed ID: 27153813
[TBL] [Abstract][Full Text] [Related]
3. Molecular mechanism of action of microtubule-stabilizing anticancer agents.
Prota AE; Bargsten K; Zurwerra D; Field JJ; Díaz JF; Altmann KH; Steinmetz MO
Science; 2013 Feb; 339(6119):587-90. PubMed ID: 23287720
[TBL] [Abstract][Full Text] [Related]
4. A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro.
Cai P; Lu P; Sharom FJ; Fang WS
Cancer Lett; 2013 Dec; 341(2):214-23. PubMed ID: 23941826
[TBL] [Abstract][Full Text] [Related]
5. Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
Matesanz R; Trigili C; Rodríguez-Salarichs J; Zanardi I; Pera B; Nogales A; Fang WS; Jímenez-Barbero J; Canales A; Barasoain I; Ojima I; Díaz JF
Bioorg Med Chem; 2014 Sep; 22(18):5078-90. PubMed ID: 25047938
[TBL] [Abstract][Full Text] [Related]
6. Molecular mobility of nitroxyl-labelled taxol during tubulin assembly.
Nicholov R; Kingston DG; Chordia MC; DiCosmo F
FEBS Lett; 1997 Mar; 405(1):73-6. PubMed ID: 9094427
[TBL] [Abstract][Full Text] [Related]
7. 3D QSAR models of interactions between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA): a survey on taxanes and epothilones.
Manetti F; Maccari L; Corelli F; Botta M
Curr Top Med Chem; 2004; 4(2):203-17. PubMed ID: 14754454
[TBL] [Abstract][Full Text] [Related]
8. Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads.
Chen QH; Kingston DG
Nat Prod Rep; 2014 Sep; 31(9):1202-26. PubMed ID: 24945566
[TBL] [Abstract][Full Text] [Related]
9. Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
Field JJ; Pera B; Calvo E; Canales A; Zurwerra D; Trigili C; Rodríguez-Salarichs J; Matesanz R; Kanakkanthara A; Wakefield SJ; Singh AJ; Jiménez-Barbero J; Northcote P; Miller JH; López JA; Hamel E; Barasoain I; Altmann KH; Díaz JF
Chem Biol; 2012 Jun; 19(6):686-98. PubMed ID: 22726683
[TBL] [Abstract][Full Text] [Related]
10. Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site.
Lo YC; Cormier O; Liu T; Nettles KW; Katzenellenbogen JA; Stearns T; Altman RB
Nat Commun; 2019 Mar; 10(1):1033. PubMed ID: 30833575
[TBL] [Abstract][Full Text] [Related]
11. Understanding tubulin/microtubule-taxane interactions: a quantitative structure-activity relationship study.
Hansch C; Verma RP
Mol Pharm; 2008; 5(1):151-61. PubMed ID: 18171015
[TBL] [Abstract][Full Text] [Related]
12. Lx2-32c, a novel taxane and its antitumor activities in vitro and in vivo.
Wang H; Li H; Zuo M; Zhang Y; Liu H; Fang W; Chen X
Cancer Lett; 2008 Sep; 268(1):89-97. PubMed ID: 18482796
[TBL] [Abstract][Full Text] [Related]
13. [Search for new MDR modifier possessing taxane skeleton].
Kobayashi J
Nihon Rinsho; 1997 May; 55(5):1135-42. PubMed ID: 9155165
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological activities of high affinity taxane-based fluorescent probes.
Li X; Barasoain I; Matesanz R; Díaz JF; Fang WS
Bioorg Med Chem Lett; 2009 Feb; 19(3):751-4. PubMed ID: 19128972
[TBL] [Abstract][Full Text] [Related]
15. FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression.
Heuer TS; Ventura R; Mordec K; Lai J; Fridlib M; Buckley D; Kemble G
EBioMedicine; 2017 Feb; 16():51-62. PubMed ID: 28159572
[TBL] [Abstract][Full Text] [Related]
16. Effects of C7 substitutions in a high affinity microtubule-binding taxane on antitumor activity and drug transport.
Xiao X; Wu J; Trigili C; Chen H; Chu JW; Zhao Y; Lu P; Sheng L; Li Y; Sharom FJ; Barasoain I; Diaz JF; Fang WS
Bioorg Med Chem Lett; 2011 Aug; 21(16):4852-6. PubMed ID: 21764308
[TBL] [Abstract][Full Text] [Related]
17. Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.
Kellogg EH; Hejab NMA; Howes S; Northcote P; Miller JH; Díaz JF; Downing KH; Nogales E
J Mol Biol; 2017 Mar; 429(5):633-646. PubMed ID: 28104363
[TBL] [Abstract][Full Text] [Related]
18. Stabilization of microtubules by taxane diterpenoids: insight from docking and MD simulations.
Yadava U; Gupta H; Roychoudhury M
J Biol Phys; 2015 Mar; 41(2):117-33. PubMed ID: 25542396
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity relationship of taxol inferring from docking taxol analogues to microtubule binding site.
Xiang F; Yu J; Yin R; Ma Y; Yu L
Z Naturforsch C J Biosci; 2009; 64(7-8):551-6. PubMed ID: 19791508
[TBL] [Abstract][Full Text] [Related]
20. Structure-activity relationships of ring C-secotaxoids. 1. Acylative modifications.
Appendino G; Bettoni P; Noncovich A; Sterner O; Fontana G; Bombardelli E; Pera P; Bernacki RJ
J Nat Prod; 2004 Feb; 67(2):184-8. PubMed ID: 14987056
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]