174 related articles for article (PubMed ID: 2231599)
1. DNA-directed alkylating agents. 3. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the length of the linker chain.
Valu KK; Gourdie TA; Boritzki TJ; Gravatt GL; Baguley BC; Wilson WR; Wakelin LP; Woodgate PD; Denny WA
J Med Chem; 1990 Nov; 33(11):3014-9. PubMed ID: 2231599
[TBL] [Abstract][Full Text] [Related]
2. DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard.
Gourdie TA; Valu KK; Gravatt GL; Boritzki TJ; Baguley BC; Wakelin LP; Wilson WR; Woodgate PD; Denny WA
J Med Chem; 1990 Apr; 33(4):1177-86. PubMed ID: 2319563
[TBL] [Abstract][Full Text] [Related]
3. DNA-directed alkylating ligands as potential antitumor agents: sequence specificity of alkylation by intercalating aniline mustards.
Prakash AS; Denny WA; Gourdie TA; Valu KK; Woodgate PD; Wakelin LP
Biochemistry; 1990 Oct; 29(42):9799-807. PubMed ID: 2271617
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of DNA-targeted spatially separated bis(aniline mustards) as potential alkylating agents with enhanced DNA cross-linking capability.
Gourdie TA; Prakash AS; Wakelin LP; Woodgate PD; Denny WA
J Med Chem; 1991 Jan; 34(1):240-8. PubMed ID: 1992124
[TBL] [Abstract][Full Text] [Related]
5. Modulation of mutagenic properties in a series of DNA-directed alkylating agents by variation of chain length and alkylator reactivity.
Ferguson LR; Turner PM; Pogai H; Denny WA
Mutat Res; 1992 Feb; 265(2):181-93. PubMed ID: 1370717
[TBL] [Abstract][Full Text] [Related]
6. DNA-directed alkylating agents. 4. 4-anilinoquinoline-based minor groove directed aniline mustards.
Gravatt GL; Baguley BC; Wilson WR; Denny WA
J Med Chem; 1991 May; 34(5):1552-60. PubMed ID: 2033580
[TBL] [Abstract][Full Text] [Related]
7. DNA-directed aniline mustards based on 9-aminoacridine: interaction with DNA.
O'Connor CJ; Denny WA; Fan JY; Gamage RS
Chem Biol Interact; 1992 Nov; 85(1):1-14. PubMed ID: 1458547
[TBL] [Abstract][Full Text] [Related]
8. Aniline mustard analogues of the DNA-intercalating agent amsacrine: DNA interaction and biological activity.
Fan JY; Valu KK; Woodgate PD; Baguley BC; Denny WA
Anticancer Drug Des; 1997 Apr; 12(3):181-203. PubMed ID: 9154110
[TBL] [Abstract][Full Text] [Related]
9. Identification of the major lesion from the reaction of an acridine-targeted aniline mustard with DNA as an adenine N1 adduct.
Boritzki TJ; Palmer BD; Coddington JM; Denny WA
Chem Res Toxicol; 1994; 7(1):41-6. PubMed ID: 8155823
[TBL] [Abstract][Full Text] [Related]
10. Microbial mutagenic effects of the DNA minor groove binder pibenzimol (Hoechst 33258) and a series of mustard analogues.
Ferguson LR; Denny WA
Mutat Res; 1995 Jun; 329(1):19-27. PubMed ID: 7539521
[TBL] [Abstract][Full Text] [Related]
11. Hypoxia-selective antitumor agents. 3. Relationships between structure and cytotoxicity against cultured tumor cells for substituted N,N-bis(2-chloroethyl)anilines.
Palmer BD; Wilson WR; Pullen SM; Denny WA
J Med Chem; 1990 Jan; 33(1):112-21. PubMed ID: 2296009
[TBL] [Abstract][Full Text] [Related]
12. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
[TBL] [Abstract][Full Text] [Related]
13. DNA-directed alkylating agents. 5. Acridinecarboxamide derivatives of (1,2-diaminoethane)dichloroplatinum(II).
Lee HH; Palmer BD; Baguley BC; Chin M; McFadyen WD; Wickham G; Thorsbourne-Palmer D; Wakelin LP; Denny WA
J Med Chem; 1992 Aug; 35(16):2983-7. PubMed ID: 1501223
[TBL] [Abstract][Full Text] [Related]
14. Differences in sequence selectivity of DNA alkylation by isomeric intercalating aniline mustards.
Prakash AS; Denny WA; Wakelin LP
Chem Biol Interact; 1990; 76(2):241-8. PubMed ID: 2225231
[TBL] [Abstract][Full Text] [Related]
15. Bacterial mutagenicity studies of DNA-intercalating aniline mustards: an insight into the mode of action of a novel class of anti-tumour drugs.
Ferguson LR; Gourdie TA; Valu KK; Denny WA
Anticancer Drug Des; 1989 Oct; 4(3):209-19. PubMed ID: 2679621
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.
Kapuriya N; Kapuriya K; Zhang X; Chou TC; Kakadiya R; Wu YT; Tsai TH; Chen YT; Lee TC; Shah A; Naliapara Y; Su TL
Bioorg Med Chem; 2008 May; 16(10):5413-23. PubMed ID: 18450456
[TBL] [Abstract][Full Text] [Related]
17. Hybrid anticancer compounds. Steroidal lactam esters of carboxylic derivatives of N,N-bis (2-chloroethyl) aniline (review).
Catsoulacos P; Catsoulacos D
Anticancer Res; 1991; 11(5):1773-7. PubMed ID: 1768051
[TBL] [Abstract][Full Text] [Related]
18. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
Smaill JB; Fan JY; Denny WA
Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
[TBL] [Abstract][Full Text] [Related]
19. Relationships between structure, toxicity and genetic effects in Salmonella typhimurium and Saccharomyces cerevisiae for substituted aniline mustards.
Ferguson LR; Palmer BD; Denny WA
Mutat Res; 1989 Sep; 224(1):95-104. PubMed ID: 2671716
[TBL] [Abstract][Full Text] [Related]
20. DNA-directed alkylating agents. 6. Synthesis and antitumor activity of DNA minor groove-targeted aniline mustard analogues of pibenzimol (Hoechst 33258).
Gravatt GL; Baguley BC; Wilson WR; Denny WA
J Med Chem; 1994 Dec; 37(25):4338-45. PubMed ID: 7527862
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]