109 related articles for article (PubMed ID: 2231604)
1. Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid.
McCague R; Rowlands MG; Barrie SE; Houghton J
J Med Chem; 1990 Nov; 33(11):3050-5. PubMed ID: 2231604
[TBL] [Abstract][Full Text] [Related]
2. Inhibitors of the P450 enzymes aromatase and lyase. Crystallographic and molecular modeling studies suggest structural features of pyridylacetic acid derivatives responsible for differences in enzyme inhibitory activity.
Laughton CA; Neidle S
J Med Chem; 1990 Nov; 33(11):3055-60. PubMed ID: 2231605
[TBL] [Abstract][Full Text] [Related]
3. Esters of 3-pyridylacetic acid that combine potent inhibition of 17 alpha-hydroxylase/C17,20-lyase (cytochrome P45017 alpha) with resistance to esterase hydrolysis.
Rowlands MG; Barrie SE; Chan F; Houghton J; Jarman M; McCague R; Potter GA
J Med Chem; 1995 Oct; 38(21):4191-7. PubMed ID: 7473546
[TBL] [Abstract][Full Text] [Related]
4. 4-pregnene-3-one-20 beta-carboxaldehyde: a potent inhibitor of 17 alpha-hydroxylase/C17,20-lyase and of 5 alpha-reductase.
Li J; Li Y; Son C; Banks P; Brodie A
J Steroid Biochem Mol Biol; 1992 May; 42(3-4):313-20. PubMed ID: 1606043
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of steroid 17 alpha-hydroxylase and C17,20-lyase in the human testis by epitestosterone.
Bicíková M; Hampl R; Hill M; Stárka L
J Steroid Biochem Mol Biol; 1993 Oct; 46(4):515-8. PubMed ID: 8217882
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of novel pyrrolidine-2,5-dione inhibitors as potential anti-tumour agents.
Ahmed S; Smith JH; Nicholls PJ; Whomsley R; Cariuk P
Drug Des Discov; 1995 Apr; 12(4):275-87. PubMed ID: 9040988
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of steroidogenic cytochrome P-450 enzymes in rat testis by ketoconazole and related imidazole anti-fungal drugs.
Kan PB; Hirst MA; Feldman D
J Steroid Biochem; 1985 Dec; 23(6A):1023-9. PubMed ID: 3841572
[TBL] [Abstract][Full Text] [Related]
8. Location of enzymes of androgen and estrogen biosynthesis in the testis of the ground squirrel (Citellus lateralis).
Pudney J; Canick JA; Clifford NM; Knapp JB; Callard GV
Biol Reprod; 1985 Nov; 33(4):971-80. PubMed ID: 3936555
[TBL] [Abstract][Full Text] [Related]
9. Tetrahydronaphthalenes: influence of heterocyclic substituents on inhibition of steroid enzymes P450 arom and P450 17.
Wächter GA; Hartmann RW; Sergejew T; Grün GL; Ledergerber D
J Med Chem; 1996 Feb; 39(4):834-41. PubMed ID: 8632407
[TBL] [Abstract][Full Text] [Related]
10. Selective inhibition of cholesterol side-chain cleavage by potential pro-drug forms of aminoglutethimide.
Jarman M; Barrie SE; Leung CS; Rowlands MG
Anticancer Drug Des; 1988 Dec; 3(3):185-90. PubMed ID: 3264700
[TBL] [Abstract][Full Text] [Related]
11. Pyridyl substituted benzocycloalkenes: new inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450 17 alpha).
Sergejew T; Hartmann RW
J Enzyme Inhib; 1994; 8(2):113-22. PubMed ID: 7539071
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and evaluation of pregnane derivatives as inhibitors of human testicular 17 alpha-hydroxylase/C17,20-lyase.
Li JS; Li Y; Son C; Brodie AM
J Med Chem; 1996 Oct; 39(21):4335-9. PubMed ID: 8863811
[TBL] [Abstract][Full Text] [Related]
13. Effects of novel 17alpha-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo.
Haidar S; Ehmer PB; Barassin S; Batzl-Hartmann C; Hartmann RW
J Steroid Biochem Mol Biol; 2003 Apr; 84(5):555-62. PubMed ID: 12767280
[TBL] [Abstract][Full Text] [Related]
14. Ketoconazole inhibition of the bifunctional cytochrome P450c17 does not affect androgen formation from the endogenous lyase substrate. The catalytic site remains refractory in the course of intermediary hydroxyprogesterone processing.
Kühn-Velten WN; Lessmann M
Biochem Pharmacol; 1992 Dec; 44(12):2371-8. PubMed ID: 1472102
[TBL] [Abstract][Full Text] [Related]
15. Pharmacology of aminoglutethimide: structure/activity relationships and receptor interactions.
Nicholls PJ; Daly MJ; Smith HJ
Breast Cancer Res Treat; 1986; 7 Suppl():S55-67. PubMed ID: 3755630
[TBL] [Abstract][Full Text] [Related]
16. R 76713 and enantiomers: selective, nonsteroidal inhibitors of the cytochrome P450-dependent oestrogen synthesis.
Vanden Bossche H; Willemsens G; Roels I; Bellens D; Moereels H; Coene MC; Le Jeune L; Lauwers W; Janssen PA
Biochem Pharmacol; 1990 Oct; 40(8):1707-18. PubMed ID: 2242008
[TBL] [Abstract][Full Text] [Related]
17. 17-Imidazolyl, pyrazolyl, and isoxazolyl androstene derivatives. Novel steroidal inhibitors of human cytochrome C17,20-lyase (P450(17 alpha).
Ling YZ; Li JS; Liu Y; Kato K; Klus GT; Brodie A
J Med Chem; 1997 Sep; 40(20):3297-304. PubMed ID: 9379450
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of testicular microsomal cytochrome P-450 (17 alpha-hydroxylase/C-17,20-lyase) by estrogens.
Onoda M; Hall PF
Endocrinology; 1981 Sep; 109(3):763-7. PubMed ID: 6973463
[TBL] [Abstract][Full Text] [Related]
19. Different inhibitory effect of etomidate and ketoconazole on the human adrenal steroid biosynthesis.
Weber MM; Lang J; Abedinpour F; Zeilberger K; Adelmann B; Engelhardt D
Clin Investig; 1993 Nov; 71(11):933-8. PubMed ID: 8312688
[TBL] [Abstract][Full Text] [Related]
20. Kinetic analysis of inhibition of human adrenal steroidogenesis by ketoconazole.
Couch RM; Muller J; Perry YS; Winter JS
J Clin Endocrinol Metab; 1987 Sep; 65(3):551-4. PubMed ID: 3497939
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
