BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

289 related articles for article (PubMed ID: 22320402)

  • 1. Amine linked flavonoid dimers as modulators for P-glycoprotein-based multidrug resistance: structure-activity relationship and mechanism of modulation.
    Chan KF; Wong IL; Kan JW; Yan CS; Chow LM; Chan TH
    J Med Chem; 2012 Mar; 55(5):1999-2014. PubMed ID: 22320402
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Flavonoids inhibit breast cancer resistance protein-mediated drug resistance: transporter specificity and structure-activity relationship.
    Katayama K; Masuyama K; Yoshioka S; Hasegawa H; Mitsuhashi J; Sugimoto Y
    Cancer Chemother Pharmacol; 2007 Nov; 60(6):789-97. PubMed ID: 17345086
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Parguerenes: Marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells.
    Huang XC; Sun YL; Salim AA; Chen ZS; Capon RJ
    Biochem Pharmacol; 2013 May; 85(9):1257-68. PubMed ID: 23415901
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug resistance (MDR) modulators.
    Dei S; Braconi L; Trezza A; Menicatti M; Contino M; Coronnello M; Chiaramonte N; Manetti D; Perrone MG; Romanelli MN; Udomtanakunchai C; Colabufo NA; Bartolucci G; Spiga O; Salerno M; Teodori E
    Eur J Med Chem; 2019 Jun; 172():71-94. PubMed ID: 30947123
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Flavonoid dimers as bivalent modulators for P-glycoprotein-based multidrug resistance: synthetic apigenin homodimers linked with defined-length poly(ethylene glycol) spacers increase drug retention and enhance chemosensitivity in resistant cancer cells.
    Chan KF; Zhao Y; Burkett BA; Wong IL; Chow LM; Chan TH
    J Med Chem; 2006 Nov; 49(23):6742-59. PubMed ID: 17154505
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reversal of P-gp and BCRP-mediated MDR by tariquidar derivatives.
    Li XQ; Wang L; Lei Y; Hu T; Zhang FL; Cho CH; To KK
    Eur J Med Chem; 2015 Aug; 101():560-72. PubMed ID: 26197160
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Jatrophane diterpenoids from Euphorbia sororia as potent modulators against P-glycoprotein-based multidrug resistance.
    Hu R; Gao J; Rozimamat R; Aisa HA
    Eur J Med Chem; 2018 Feb; 146():157-170. PubMed ID: 29407947
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel structure-activity relationships and selectivity profiling of cage dimeric 1,4-dihydropyridines as multidrug resistance (MDR) modulators.
    Coburger C; Wollmann J; Krug M; Baumert C; Seifert M; Molnár J; Lage H; Hilgeroth A
    Bioorg Med Chem; 2010 Jul; 18(14):4983-90. PubMed ID: 20598550
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-activity relationship study of permethyl ningalin B analogues as P-glycoprotein chemosensitizers.
    Bin JW; Wong IL; Hu X; Yu ZX; Xing LF; Jiang T; Chow LM; Biao WS
    J Med Chem; 2013 Nov; 56(22):9057-70. PubMed ID: 24171478
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer FD18 Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft in Vivo.
    Yan CS; Wong IL; Chan KF; Kan JW; Chong TC; Law MC; Zhao Y; Chan SW; Chan TH; Chow LM
    Mol Pharm; 2015 Oct; 12(10):3507-17. PubMed ID: 26291333
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.
    Limtrakul P; Chearwae W; Shukla S; Phisalphong C; Ambudkar SV
    Mol Cell Biochem; 2007 Feb; 296(1-2):85-95. PubMed ID: 16960658
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2.
    Dai CL; Liang YJ; Wang YS; Tiwari AK; Yan YY; Wang F; Chen ZS; Tong XZ; Fu LW
    Cancer Lett; 2009 Jun; 279(1):74-83. PubMed ID: 19232821
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR).
    Dei S; Romanelli MN; Manetti D; Chiaramonte N; Coronnello M; Salerno M; Teodori E
    Bioorg Med Chem; 2018 Jan; 26(1):50-64. PubMed ID: 29162309
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance.
    Muñoz-Martínez F; Lu P; Cortés-Selva F; Pérez-Victoria JM; Jiménez IA; Ravelo AG; Sharom FJ; Gamarro F; Castanys S
    Cancer Res; 2004 Oct; 64(19):7130-8. PubMed ID: 15466210
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Arylamino Esters As P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity.
    Teodori E; Dei S; Floriddia E; Perrone MG; Manetti D; Romanelli MN; Contino M; Colabufo NA
    ChemMedChem; 2015 Aug; 10(8):1339-43. PubMed ID: 26012726
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thieno[2,3-b]pyridines--a new class of multidrug resistance (MDR) modulators.
    Krauze A; Grinberga S; Krasnova L; Adlere I; Sokolova E; Domracheva I; Shestakova I; Andzans Z; Duburs G
    Bioorg Med Chem; 2014 Nov; 22(21):5860-70. PubMed ID: 25311564
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Flavonoid dimers as bivalent modulators for p-glycoprotein-based multidrug resistance: structure-activity relationships.
    Chan KF; Zhao Y; Chow TW; Yan CS; Ma DL; Burkett BA; Wong IL; Chow LM; Chan TH
    ChemMedChem; 2009 Apr; 4(4):594-614. PubMed ID: 19288491
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rhinacanthin-C enhances doxorubicin cytotoxicity via inhibiting the functions of P-glycoprotein and MRP2 in breast cancer cells.
    Chaisit T; Siripong P; Jianmongkol S
    Eur J Pharmacol; 2017 Jan; 795():50-57. PubMed ID: 27916559
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HM30181 Derivatives as Novel Potent and Selective Inhibitors of the Breast Cancer Resistance Protein (BCRP/ABCG2).
    Köhler SC; Wiese M
    J Med Chem; 2015 May; 58(9):3910-21. PubMed ID: 25855895
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Icariin enhances cytotoxicity of doxorubicin in human multidrug-resistant osteosarcoma cells by inhibition of ABCB1 and down-regulation of the PI3K/Akt pathway.
    Wang Z; Yang L; Xia Y; Guo C; Kong L
    Biol Pharm Bull; 2015; 38(2):277-84. PubMed ID: 25747987
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.