BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 22321511)

  • 1. Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes.
    Qiao S; Lamore SD; Cabello CM; Lesson JL; Muñoz-Rodriguez JL; Wondrak GT
    Biochem Pharmacol; 2012 May; 83(9):1229-40. PubMed ID: 22321511
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells.
    Davis AL; Qiao S; Lesson JL; Rojo de la Vega M; Park SL; Seanez CM; Gokhale V; Cabello CM; Wondrak GT
    J Biol Chem; 2015 Jan; 290(3):1623-38. PubMed ID: 25477506
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis.
    Cabello CM; Lamore SD; Bair WB; Qiao S; Azimian S; Lesson JL; Wondrak GT
    Invest New Drugs; 2012 Aug; 30(4):1289-301. PubMed ID: 21547369
    [TBL] [Abstract][Full Text] [Related]  

  • 4. D-Penicillamine targets metastatic melanoma cells with induction of the unfolded protein response (UPR) and Noxa (PMAIP1)-dependent mitochondrial apoptosis.
    Qiao S; Cabello CM; Lamore SD; Lesson JL; Wondrak GT
    Apoptosis; 2012 Oct; 17(10):1079-94. PubMed ID: 22843330
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1.
    Cabello CM; Bair WB; Bause AS; Wondrak GT
    Biochem Pharmacol; 2009 Aug; 78(4):344-54. PubMed ID: 19394313
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells.
    Qin JZ; Ziffra J; Stennett L; Bodner B; Bonish BK; Chaturvedi V; Bennett F; Pollock PM; Trent JM; Hendrix MJ; Rizzo P; Miele L; Nickoloff BJ
    Cancer Res; 2005 Jul; 65(14):6282-93. PubMed ID: 16024630
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thiostrepton, a natural compound that triggers heat shock response and apoptosis in human cancer cells: a proteomics investigation.
    Sandu C; Ngounou Wetie AG; Darie CC; Steller H
    Adv Exp Med Biol; 2014; 806():443-51. PubMed ID: 24952196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.
    Fernández Y; Verhaegen M; Miller TP; Rush JL; Steiner P; Opipari AW; Lowe SW; Soengas MS
    Cancer Res; 2005 Jul; 65(14):6294-304. PubMed ID: 16024631
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Zinc pyrithione impairs zinc homeostasis and upregulates stress response gene expression in reconstructed human epidermis.
    Lamore SD; Wondrak GT
    Biometals; 2011 Oct; 24(5):875-90. PubMed ID: 21424779
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells.
    Lamore SD; Cabello CM; Wondrak GT
    Cell Stress Chaperones; 2010 May; 15(3):309-22. PubMed ID: 19809895
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinoma.
    Cabello CM; Lamore SD; Bair WB; Davis AL; Azimian SM; Wondrak GT
    Free Radic Res; 2011 Mar; 45(3):276-92. PubMed ID: 21034357
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Repurposing the Electron Transfer Reactant Phenazine Methosulfate (PMS) for the Apoptotic Elimination of Malignant Melanoma Cells through Induction of Lethal Oxidative and Mitochondriotoxic Stress.
    Hua AB; Justiniano R; Perer J; Park SL; Li H; Cabello CM; Wondrak GT
    Cancers (Basel); 2019 Apr; 11(5):. PubMed ID: 31035569
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib.
    Neznanov N; Komarov AP; Neznanova L; Stanhope-Baker P; Gudkov AV
    Oncotarget; 2011 Mar; 2(3):209-21. PubMed ID: 21444945
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hsp70B' regulation and function.
    Noonan EJ; Place RF; Giardina C; Hightower LE
    Cell Stress Chaperones; 2007; 12(3):219-29. PubMed ID: 17915554
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition.
    Nikiforov MA; Riblett M; Tang WH; Gratchouck V; Zhuang D; Fernandez Y; Verhaegen M; Varambally S; Chinnaiyan AM; Jakubowiak AJ; Soengas MS
    Proc Natl Acad Sci U S A; 2007 Dec; 104(49):19488-93. PubMed ID: 18042711
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hsp70B' regulation and function.
    Noonan EJ; Place RF; Giardina C; Hightower LE
    Cell Stress Chaperones; 2007; 12(4):393-402. PubMed ID: 18229458
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
    Gomez-Bougie P; Wuillème-Toumi S; Ménoret E; Trichet V; Robillard N; Philippe M; Bataille R; Amiot M
    Cancer Res; 2007 Jun; 67(11):5418-24. PubMed ID: 17545623
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA.
    Qin JZ; Xin H; Sitailo LA; Denning MF; Nickoloff BJ
    Cancer Res; 2006 Oct; 66(19):9636-45. PubMed ID: 17018621
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Localization of heat shock protein HSPA6 (HSP70B') to sites of transcription in cultured differentiated human neuronal cells following thermal stress.
    Khalouei S; Chow AM; Brown IR
    J Neurochem; 2014 Dec; 131(6):743-54. PubMed ID: 25319762
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells.
    Selimovic D; Porzig BB; El-Khattouti A; Badura HE; Ahmad M; Ghanjati F; Santourlidis S; Haikel Y; Hassan M
    Cell Signal; 2013 Jan; 25(1):308-18. PubMed ID: 23079083
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.