BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 22322883)

  • 1. Disulfiram, an old drug with new potential therapeutic uses for human hematological malignancies.
    Conticello C; Martinetti D; Adamo L; Buccheri S; Giuffrida R; Parrinello N; Lombardo L; Anastasi G; Amato G; Cavalli M; Chiarenza A; De Maria R; Giustolisi R; Gulisano M; Di Raimondo F
    Int J Cancer; 2012 Nov; 131(9):2197-203. PubMed ID: 22322883
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disulfiram/copper causes ROS levels alteration, cell cycle inhibition, and apoptosis in acute myeloid leukaemia cell lines with modulation in the expression of related genes.
    Hassani S; Ghaffari P; Chahardouli B; Alimoghaddam K; Ghavamzadeh A; Alizadeh S; Ghaffari SH
    Biomed Pharmacother; 2018 Mar; 99():561-569. PubMed ID: 29902866
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disulfiram induces copper-dependent stimulation of reactive oxygen species and activation of the extrinsic apoptotic pathway in melanoma.
    Morrison BW; Doudican NA; Patel KR; Orlow SJ
    Melanoma Res; 2010 Feb; 20(1):11-20. PubMed ID: 19966593
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disulfiram anti-cancer efficacy without copper overload is enhanced by extracellular H2O2 generation: antagonism by tetrathiomolybdate.
    Calderon-Aparicio A; Strasberg-Rieber M; Rieber M
    Oncotarget; 2015 Oct; 6(30):29771-81. PubMed ID: 26356671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disulfiram/copper markedly induced myeloma cell apoptosis through activation of JNK and intrinsic and extrinsic apoptosis pathways.
    Xu Y; Zhou Q; Feng X; Dai Y; Jiang Y; Jiang W; Liu X; Xing X; Wang Y; Ni Y; Zheng C
    Biomed Pharmacother; 2020 Jun; 126():110048. PubMed ID: 32145587
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors.
    Pei XY; Dai Y; Grant S
    Clin Cancer Res; 2004 Jun; 10(11):3839-52. PubMed ID: 15173093
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo.
    Huang H; Liao Y; Liu N; Hua X; Cai J; Yang C; Long H; Zhao C; Chen X; Lan X; Zang D; Wu J; Li X; Shi X; Wang X; Liu J
    Oncotarget; 2016 Jan; 7(3):2796-808. PubMed ID: 26625200
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The disulfiram/copper complex induces apoptosis and inhibits tumour growth in human osteosarcoma by activating the ROS/JNK signalling pathway.
    Guo W; Zhang X; Lin L; Wang H; He E; Wang G; Zhao Q
    J Biochem; 2021 Oct; 170(2):275-287. PubMed ID: 33792698
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2.
    Xu B; Wang S; Li R; Chen K; He L; Deng M; Kannappan V; Zha J; Dong H; Wang W
    Cell Death Dis; 2017 May; 8(5):e2797. PubMed ID: 28518151
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer.
    Allensworth JL; Evans MK; Bertucci F; Aldrich AJ; Festa RA; Finetti P; Ueno NT; Safi R; McDonnell DP; Thiele DJ; Van Laere S; Devi GR
    Mol Oncol; 2015 Jun; 9(6):1155-68. PubMed ID: 25769405
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disulfiram chelated with copper promotes apoptosis in human breast cancer cells by impairing the mitochondria functions.
    Yang Y; Zhang K; Wang Y; Li M; Sun X; Liang Z; Wang L; Chen L; Yang H; Zhu L
    Scanning; 2016 Nov; 38(6):825-836. PubMed ID: 27353661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Disulfiram overcomes bortezomib and cytarabine resistance in Down-syndrome-associated acute myeloid leukemia cells.
    Bista R; Lee DW; Pepper OB; Azorsa DO; Arceci RJ; Aleem E
    J Exp Clin Cancer Res; 2017 Feb; 36(1):22. PubMed ID: 28143565
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disulfiram induces apoptosis in human melanoma cells: a redox-related process.
    Cen D; Gonzalez RI; Buckmeier JA; Kahlon RS; Tohidian NB; Meyskens FL
    Mol Cancer Ther; 2002 Jan; 1(3):197-204. PubMed ID: 12467214
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disulfiram/copper shows potent cytotoxic effects on myelodysplastic syndromes via inducing Bip-mediated apoptosis and suppressing autophagy.
    Zha J; Bi S; Deng M; Chen K; Shi P; Feng L; He J; Pu X; Guo C; Zhao H; Li Z; Jiang Y; Song H; Xu B
    Eur J Pharmacol; 2021 Jul; 902():174107. PubMed ID: 33865831
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibitory effect on ovarian cancer ALDH+ stem-like cells by Disulfiram and Copper treatment through ALDH and ROS modulation.
    Guo F; Yang Z; Kulbe H; Albers AE; Sehouli J; Kaufmann AM
    Biomed Pharmacother; 2019 Oct; 118():109371. PubMed ID: 31545281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oxidative stress and c-Jun-amino-terminal kinase activation involved in apoptosis of primary astrocytes induced by disulfiram-Cu(2+) complex.
    Chen SH; Liu SH; Liang YC; Lin JK; Lin-Shiau SY
    Eur J Pharmacol; 2001 Mar; 414(2-3):177-88. PubMed ID: 11239917
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.
    Kang MH; Wan Z; Kang YH; Sposto R; Reynolds CP
    J Natl Cancer Inst; 2008 Apr; 100(8):580-95. PubMed ID: 18398104
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells.
    Cheng YY; Yang JS; Tsai SC; Liaw CC; Chung JG; Huang LJ; Lee KH; Lu CC; Chien HC; Tsuzuki M; Kuo SC
    Oncol Rep; 2012 Oct; 28(4):1482-90. PubMed ID: 22825350
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Copper ions regulate cytotoxicity of disulfiram to myeloid leukemia cells.
    Navrátilová J; Jungová P; Vanhara P; Preisler J; Kanicky V; Smarda J
    Int J Mol Med; 2009 Nov; 24(5):661-70. PubMed ID: 19787200
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of lung adenocarcinoma by combinations of sulfasalazine (SAS) and disulfiram-copper (DSF-Cu) in cell line models and mice.
    Bagherpoor AJ; Shameem M; Luo X; Seelig D; Kassie F
    Carcinogenesis; 2023 Jun; 44(4):291-303. PubMed ID: 37053033
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.