BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 22331470)

  • 1. The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector.
    Neel NF; Rossman KL; Martin TD; Hayes TK; Yeh JJ; Der CJ
    Mol Cell Biol; 2012 Apr; 32(8):1374-86. PubMed ID: 22331470
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation.
    Kidd AR; Snider JL; Martin TD; Graboski SF; Der CJ; Cox AD
    Int J Radiat Oncol Biol Phys; 2010 Sep; 78(1):205-12. PubMed ID: 20619549
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction.
    Fenwick RB; Campbell LJ; Rajasekar K; Prasannan S; Nietlispach D; Camonis J; Owen D; Mott HR
    Structure; 2010 Aug; 18(8):985-95. PubMed ID: 20696399
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms.
    Vigil D; Martin TD; Williams F; Yeh JJ; Campbell SL; Der CJ
    J Biol Chem; 2010 Nov; 285(45):34729-40. PubMed ID: 20801877
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ral GTPase-activating protein regulates the malignancy of pancreatic ductal adenocarcinoma.
    Yoshimachi S; Shirakawa R; Cao M; Trinh DA; Gao P; Sakata N; Miyazaki K; Goto K; Miura T; Ariake K; Maeda S; Masuda K; Ishida M; Ohtsuka H; Unno M; Horiuchi H
    Cancer Sci; 2021 Aug; 112(8):3064-3073. PubMed ID: 34009715
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ral GTPases in tumorigenesis: emerging from the shadows.
    Kashatus DF
    Exp Cell Res; 2013 Sep; 319(15):2337-42. PubMed ID: 23830877
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation and involvement of Ral GTPases in colorectal cancer.
    Martin TD; Samuel JC; Routh ED; Der CJ; Yeh JJ
    Cancer Res; 2011 Jan; 71(1):206-15. PubMed ID: 21199803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thermodynamic mapping of effector protein interfaces with RalA and RalB.
    Campbell LJ; Peppa M; Crabtree MD; Shafiq A; McGough NF; Mott HR; Owen D
    Biochemistry; 2015 Feb; 54(6):1380-9. PubMed ID: 25621740
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential involvement of RalA and RalB in colorectal cancer.
    Martin TD; Der CJ
    Small GTPases; 2012; 3(2):126-30. PubMed ID: 22790202
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RalBP1 is necessary for metastasis of human cancer cell lines.
    Wu Z; Owens C; Chandra N; Popovic K; Conaway M; Theodorescu D
    Neoplasia; 2010 Dec; 12(12):1003-12. PubMed ID: 21170262
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sec5 and Exo84 foster oncogenic ras-mediated tumorigenesis.
    Issaq SH; Lim KH; Counter CM
    Mol Cancer Res; 2010 Feb; 8(2):223-31. PubMed ID: 20145037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.
    Hurd CA; Brear P; Revell J; Ross S; Mott HR; Owen D
    J Biol Chem; 2021; 296():100101. PubMed ID: 33214225
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of RalA is critical for Ras-induced tumorigenesis of human cells.
    Lim KH; Baines AT; Fiordalisi JJ; Shipitsin M; Feig LA; Cox AD; Der CJ; Counter CM
    Cancer Cell; 2005 Jun; 7(6):533-45. PubMed ID: 15950903
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module.
    Wang S; Chen X; Crisman L; Dou X; Winborn CS; Wan C; Puscher H; Yin Q; Kennedy MJ; Shen J
    Sci Adv; 2023 Feb; 9(8):eade2540. PubMed ID: 36812304
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The RAL Enigma: Distinct Roles of RALA and RALB in Cancer.
    Richardson DS; Spehar JM; Han DT; Chakravarthy PA; Sizemore ST
    Cells; 2022 May; 11(10):. PubMed ID: 35626682
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery and characterization of small molecules that target the GTPase Ral.
    Yan C; Liu D; Li L; Wempe MF; Guin S; Khanna M; Meier J; Hoffman B; Owens C; Wysoczynski CL; Nitz MD; Knabe WE; Ahmed M; Brautigan DL; Paschal BM; Schwartz MA; Jones DN; Ross D; Meroueh SO; Theodorescu D
    Nature; 2014 Nov; 515(7527):443-7. PubMed ID: 25219851
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.
    Lim KH; O'Hayer K; Adam SJ; Kendall SD; Campbell PM; Der CJ; Counter CM
    Curr Biol; 2006 Dec; 16(24):2385-94. PubMed ID: 17174914
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RalB directly triggers invasion downstream Ras by mobilizing the Wave complex.
    Zago G; Veith I; Singh MK; Fuhrmann L; De Beco S; Remorino A; Takaoka S; Palmeri M; Berger F; Brandon N; El Marjou A; Vincent-Salomon A; Camonis J; Coppey M; Parrini MC
    Elife; 2018 Oct; 7():. PubMed ID: 30320548
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76).
    Herlevsen MC; Theodorescu D
    Biochem Biophys Res Commun; 2007 Oct; 362(1):56-62. PubMed ID: 17706599
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and function of RLIP76 (RalBP1): an intersection point between Ras and Rho signalling.
    Mott HR; Owen D
    Biochem Soc Trans; 2014 Feb; 42(1):52-8. PubMed ID: 24450627
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.