BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 22334096)

  • 1. N-succinylaspart-1-yl celecoxib is a potential colon-specific prodrug of celecoxib with improved therapeutic properties.
    Lee Y; Kim J; Kim H; Kang S; Yoon JH; Kim DD; Kim YM; Jung Y
    J Pharm Sci; 2012 May; 101(5):1831-42. PubMed ID: 22334096
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Colon-specific delivery of celecoxib is a potential strategy to improve toxicological and pharmacological properties of the selective Cox-2 inhibitor: implication in treatment of familiar adenomatous polyposis.
    Lee Y; Kim H; Kim W; Yoon JH; Jeong SH; Jung Y
    J Drug Target; 2012 Jul; 20(6):524-34. PubMed ID: 22632102
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Colon-targeted celecoxib ameliorates TNBS-induced rat colitis: a potential pharmacologic mechanism and therapeutic advantages.
    Lee Y; Kim W; Hong S; Park H; Yum S; Yoon JH; Jung Y
    Eur J Pharmacol; 2014 Mar; 726():49-56. PubMed ID: 24462351
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Celecoxib coupled to dextran via a glutamic acid linker yields a polymeric prodrug suitable for colonic delivery.
    Lee Y; Kim J; Kim W; Nam J; Jeong S; Lee S; Yoo JW; Kim MS; Jung Y
    Drug Des Devel Ther; 2015; 9():4105-13. PubMed ID: 26251576
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Colonic delivery of celecoxib is a potential pharmaceutical strategy for repositioning the selective COX-2 inhibitor as an anti-colitic agent.
    Kim W; Lee Y; Jeong S; Nam J; Lee S; Jung Y
    Arch Pharm Res; 2015 Oct; 38(10):1830-8. PubMed ID: 25860026
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of N-nicotinoyl-2-{2-(2-methyl-5-nitroimidazol-1-yl)ethyloxy}-D,L-glycine as a colon-specific prodrug of metronidazole.
    Kim D; Hong S; Jung S; Jung Y; Kim YM
    J Pharm Sci; 2009 Nov; 98(11):4161-9. PubMed ID: 19283770
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor.
    Rao CV; Indranie C; Simi B; Manning PT; Connor JR; Reddy BS
    Cancer Res; 2002 Jan; 62(1):165-70. PubMed ID: 11782374
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of glycine-bearing celecoxib derivatives as a colon-specific mutual prodrug acting on nuclear factor-κB, an anti-inflammatory target.
    Lee S; Lee Y; Kim W; Nam J; Jeong S; Yoo JW; Kim MS; Moon HR; Jung Y
    Drug Des Devel Ther; 2015; 9():4227-37. PubMed ID: 26300626
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis.
    Reddy BS; Hirose Y; Lubet R; Steele V; Kelloff G; Paulson S; Seibert K; Rao CV
    Cancer Res; 2000 Jan; 60(2):293-7. PubMed ID: 10667579
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Up-regulation of p53 and mitochondrial signaling pathway in apoptosis by a combination of COX-2 inhibitor, Celecoxib and Dolastatin 15, a marine mollusk linear peptide in experimental colon carcinogenesis.
    Piplani H; Vaish V; Rana C; Sanyal SN
    Mol Carcinog; 2013 Nov; 52(11):845-58. PubMed ID: 22623379
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of sulfate conjugated metronidazole as a colon-specific prodrug of metronidazole.
    Kim H; Lee Y; Yoo H; Kim J; Kong H; Yoon JH; Jung Y; Kim YM
    J Drug Target; 2012 Apr; 20(3):255-63. PubMed ID: 22118327
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer.
    Wang L; Chen W; Xie X; He Y; Bai X
    Exp Oncol; 2008 Mar; 30(1):42-51. PubMed ID: 18438340
    [TBL] [Abstract][Full Text] [Related]  

  • 13. pH-sensitive nanoparticles of curcumin-celecoxib combination: evaluating drug synergy in ulcerative colitis model.
    Gugulothu D; Kulkarni A; Patravale V; Dandekar P
    J Pharm Sci; 2014 Feb; 103(2):687-96. PubMed ID: 24375287
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of selective cyclooxygenase-2 inhibitor and omega-3 fatty acid on serum interleukin-1beta, osteocalcin, and C-reactive protein levels in rats.
    Vardar-Sengül S; Buduneli N; Buduneli E; Baylas H; Atilla G; Lappin D; Kinane DF
    J Periodontol; 2006 Apr; 77(4):657-63. PubMed ID: 16584347
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A nitrophenyl-based prodrug type for colorectal targeting of prednisolone, budesonide and celecoxib.
    Marquez Ruiz JF; Kedziora K; Pigott M; Keogh B; Windle H; Gavin J; Kelleher DP; Gilmer JF
    Bioorg Med Chem Lett; 2013 Mar; 23(6):1693-8. PubMed ID: 23416011
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Preparation and Evaluation of Amino Acid Conjugates of Celecoxib as Prodrugs to Improve the Pharmacokinetic and Therapeutic Properties of Celecoxib.
    Lee Y; Kim J; Kim W; Yoon IS; Jung Y
    Pharmaceutics; 2020 Oct; 12(11):. PubMed ID: 33143357
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of 5-aminosalicyltaurine as a colon-specific prodrug of 5-aminosalicylic acid for treatment of experimental colitis.
    Jung Y; Kim HH; Kim H; Kong H; Choi B; Yang Y; Kim Y
    Eur J Pharm Sci; 2006 May; 28(1-2):26-33. PubMed ID: 16455235
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apoptosis of murine lupus T cells induced by the selective cyclooxygenase-2 inhibitor celecoxib: molecular mechanisms and therapeutic potential.
    Yang P; Zhang Y; Ping L; Gao XM
    Int Immunopharmacol; 2007 Nov; 7(11):1414-21. PubMed ID: 17761345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclooxygenase-2 inhibitor suppresses tumour progression of prostate cancer bone metastases in nude mice.
    Garcia M; Velez R; Romagosa C; Majem B; Pedrola N; Olivan M; Rigau M; Guiu M; Gomis RR; Morote J; Reventós J; Doll A
    BJU Int; 2014 May; 113(5b):E164-77. PubMed ID: 24127882
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis.
    Kawamori T; Rao CV; Seibert K; Reddy BS
    Cancer Res; 1998 Feb; 58(3):409-12. PubMed ID: 9458081
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.