These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 22339065)

  • 1. Methylenedioxy- and ethylenedioxy-fused indolocarbazoles: potent human topoisomerase I inhibitors and antitumor agents.
    Zembower DE; Xie Y; Koohang A; Kuffel MJ; Ames MM; Zhou Y; Mishra R; Mar AA; Flavin MT; Xu ZQ
    Anticancer Agents Med Chem; 2012 Nov; 12(9):1117-31. PubMed ID: 22339065
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of novel indole derivatives as promising DNA-binding agents and evaluation of antitumor and antitopoisomerase I activities.
    Lafayette EA; de Almeida SMV; Cavalcanti Santos RV; de Oliveira JF; Amorim CADC; da Silva RMF; Pitta MGDR; Pitta IDR; de Moura RO; de Carvalho Júnior LB; de Melo Rêgo MJB; de Lima MDCA
    Eur J Med Chem; 2017 Aug; 136():511-522. PubMed ID: 28531811
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles as a new class of anti-cancer agents.
    Pierce LT; Cahill MM; Winfield HJ; McCarthy FO
    Eur J Med Chem; 2012 Oct; 56():292-300. PubMed ID: 22910137
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, topoisomerase-targeting activity and growth inhibition of lycobetaine analogs.
    Baechler SA; Fehr M; Habermeyer M; Hofmann A; Merz KH; Fiebig HH; Marko D; Eisenbrand G
    Bioorg Med Chem; 2013 Feb; 21(3):814-23. PubMed ID: 23266176
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Carbazole Aminoalcohols Induce Antiproliferation and Apoptosis of Human Tumor Cells by Inhibiting Topoisomerase I.
    Wang W; Sun X; Sun D; Li S; Yu Y; Yang T; Yao J; Chen Z; Duan L
    ChemMedChem; 2016 Dec; 11(24):2675-2681. PubMed ID: 27879063
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of lapachol derivatives possessing indole scaffolds as topoisomerase I inhibitors.
    Zhang C; Qu Y; Niu B
    Bioorg Med Chem; 2016 Nov; 24(22):5781-5786. PubMed ID: 27667553
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors.
    Zhang C; Li S; Ji L; Liu S; Li Z; Li S; Meng X
    Bioorg Med Chem Lett; 2015 Oct; 25(20):4693-6. PubMed ID: 26384290
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rebeccamycin analogues from indolo[2,3-c]carbazole.
    Voldoire A; Sancelme M; Prudhomme M; Colson P; Houssier C; Bailly C; Léonce S; Lambel S
    Bioorg Med Chem; 2001 Feb; 9(2):357-65. PubMed ID: 11249128
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, molecular modeling and biological evaluation of new benzo[4,5]thieno[3,2-b]pyran derivatives as topoisomerase I-DNA binary complex poisons.
    Ahmed EM; Khalil NA; Zaher AF; Alhamaky SM; El-Zoghbi MS
    Bioorg Chem; 2021 Jul; 112():104915. PubMed ID: 33905973
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
    Cheng P; Zhu L; Guo W; Liu W; Yao J; Dong G; Zhang Y; Zhuang C; Sheng C; Miao Z; Zhang W
    J Enzyme Inhib Med Chem; 2012 Jun; 27(3):437-42. PubMed ID: 21770860
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and biological evaluation of new β-carboline-bisindole compounds as DNA binding, photocleavage agents and topoisomerase I inhibitors.
    Kovvuri J; Nagaraju B; Nayak VL; Akunuri R; Rao MPN; Ajitha A; Nagesh N; Kamal A
    Eur J Med Chem; 2018 Jan; 143():1563-1577. PubMed ID: 29129513
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of 9-(heteroarylmethylidene)amino derivatives of homocamptothecin with biological activities.
    Guo W; Miao Z; Sheng C; Yao J; Liu W; Zhu L; Zhang Y; Cheng P; Dong G; Zhuang C; Zhang W
    Chem Biodivers; 2011 Jul; 8(7):1266-73. PubMed ID: 21766447
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines.
    Konkoľová E; Hudáčová M; Hamuľaková S; Jendželovský R; Vargová J; Ševc J; Fedoročko P; Kožurková M
    Molecules; 2021 Feb; 26(4):. PubMed ID: 33672694
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluations of novel indenoisoquinolines as topoisomerase I inhibitors.
    Zhang X; Wang R; Zhao L; Lu N; Wang J; You Q; Li Z; Guo Q
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1276-81. PubMed ID: 22079759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles.
    Singh M; Tandon V
    Eur J Med Chem; 2011 Feb; 46(2):659-69. PubMed ID: 21186067
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Syntheses and biological evaluation of indolocarbazoles, analogues of rebeccamycin, modified at the imide heterocycle.
    Moreau P; Anizon F; Sancelme M; Prudhomme M; Bailly C; Carrasco C; Ollier M; Sevère D; Riou JF; Fabbro D; Meyer T; Aubertin AM
    J Med Chem; 1998 May; 41(10):1631-40. PubMed ID: 9572888
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pyrroloquinolinone-based dual topoisomerase I/II inhibitor.
    Dalla Via L; Marzaro G; Ferrarese A; Gia O; Chilin A
    Eur J Med Chem; 2014 Apr; 77():103-9. PubMed ID: 24631729
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study.
    Karki R; Jun KY; Kadayat TM; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Eur J Med Chem; 2016 May; 113():228-45. PubMed ID: 26945111
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel securinine derivatives as topoisomerase I based antitumor agents.
    Hou W; Wang ZY; Peng CK; Lin J; Liu X; Chang YQ; Xu J; Jiang RW; Lin H; Sun PH; Chen WM
    Eur J Med Chem; 2016 Oct; 122():149-163. PubMed ID: 27344492
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of novel ellipticines as potential anti-cancer agents.
    Deane FM; O'Sullivan EC; Maguire AR; Gilbert J; Sakoff JA; McCluskey A; McCarthy FO
    Org Biomol Chem; 2013 Feb; 11(8):1334-44. PubMed ID: 23314103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.