These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

96 related articles for article (PubMed ID: 22339212)

  • 1. New β-strand templates constrained by Huisgen cycloaddition.
    Pehere AD; Abell AD
    Org Lett; 2012 Mar; 14(5):1330-3. PubMed ID: 22339212
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and extended activity of triazole-containing macrocyclic protease inhibitors.
    Pehere AD; Pietsch M; Gütschow M; Neilsen PM; Pedersen DS; Nguyen S; Zvarec O; Sykes MJ; Callen DF; Abell AD
    Chemistry; 2013 Jun; 19(24):7975-81. PubMed ID: 23606616
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New tripeptide-based macrocyclic calpain inhibitors formed by N-alkylation of histidine.
    Chen H; Jiao W; Jones MA; Coxon JM; Morton JD; Bickerstaffe R; Pehere AD; Zvarec O; Abell AD
    Chem Biodivers; 2012 Nov; 9(11):2473-84. PubMed ID: 23161629
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Countering cooperative effects in protease inhibitors using constrained beta-strand-mimicking templates in focused combinatorial libraries.
    Reid RC; Pattenden LK; Tyndall JD; Martin JL; Walsh T; Fairlie DP
    J Med Chem; 2004 Mar; 47(7):1641-51. PubMed ID: 15027855
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A template-based approach to inhibitors of calpain 2, 20S proteasome, and HIV-1 protease.
    Jones SA; Neilsen PM; Siew L; Callen DF; Goldfarb NE; Dunn BM; Abell AD
    ChemMedChem; 2013 Dec; 8(12):1918-21. PubMed ID: 24130198
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular modeling, synthesis, and biological evaluation of macrocyclic calpain inhibitors.
    Abell AD; Jones MA; Coxon JM; Morton JD; Aitken SG; McNabb SB; Lee HY; Mehrtens JM; Alexander NA; Stuart BG; Neffe AT; Bickerstaffe R
    Angew Chem Int Ed Engl; 2009; 48(8):1455-8. PubMed ID: 19145612
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, antiviral activity, and conformational studies of a P3 aza-peptide analog of a potent macrocyclic tripeptide HCV protease inhibitor.
    Randolph JT; Zhang X; Huang PP; Klein LL; Kurtz KA; Konstantinidis AK; He W; Kati WM; Kempf DJ
    Bioorg Med Chem Lett; 2008 Apr; 18(8):2745-50. PubMed ID: 18375121
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads.
    Huang Y; Strobel ED; Ho CY; Reynolds CH; Conway KA; Piesvaux JA; Brenneman DE; Yohrling GJ; Moore Arnold H; Rosenthal D; Alexander RS; Tounge BA; Mercken M; Vandermeeren M; Parker MH; Reitz AB; Baxter EW
    Bioorg Med Chem Lett; 2010 May; 20(10):3158-60. PubMed ID: 20399652
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Macrocyclic protease inhibitors with reduced peptide character.
    Chua KC; Pietsch M; Zhang X; Hautmann S; Chan HY; Bruning JB; Gütschow M; Abell AD
    Angew Chem Int Ed Engl; 2014 Jul; 53(30):7828-31. PubMed ID: 24903745
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of depeptidized macrocyclic inhibitors of hepatitis C NS3-4A protease using structure-based drug design.
    Venkatraman S; Njoroge FG; Girijavallabhan VM; Madison VS; Yao NH; Prongay AJ; Butkiewicz N; Pichardo J
    J Med Chem; 2005 Aug; 48(16):5088-91. PubMed ID: 16078825
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Macrocyclic inhibitors of the malarial aspartic proteases plasmepsin I, II, and IV.
    Ersmark K; Nervall M; Gutiérrez-de-Terán H; Hamelink E; Janka LK; Clemente JC; Dunn BM; Gogoll A; Samuelsson B; Qvist J; Hallberg A
    Bioorg Med Chem; 2006 Apr; 14(7):2197-208. PubMed ID: 16307884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and biological activity of m-tyrosine-based 16- and 17-membered macrocyclic inhibitors of hepatitis C virus NS3 serine protease.
    Chen KX; Njoroge FG; Pichardo J; Prongay A; Butkiewicz N; Yao N; Madison V; Girijavallabhan V
    J Med Chem; 2005 Oct; 48(20):6229-35. PubMed ID: 16190750
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1,2-Benzothiazine 1,1-dioxide P(2)-P(3) peptide mimetic aldehyde calpain I inhibitors.
    Wells GJ; Tao M; Josef KA; Bihovsky R
    J Med Chem; 2001 Oct; 44(21):3488-503. PubMed ID: 11585453
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Efficient access to new chemical space through flow--construction of druglike macrocycles through copper-surface-catalyzed azide-alkyne cycloaddition reactions.
    Bogdan AR; James K
    Chemistry; 2010 Dec; 16(48):14506-12. PubMed ID: 21038332
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Studies on aromatic compounds: inhibition of calpain I by biphenyl derivatives and peptide-biphenyl hybrids.
    Montero A; Alonso M; Benito E; Chana A; Mann E; Navas JM; Herradón B
    Bioorg Med Chem Lett; 2004 Jun; 14(11):2753-7. PubMed ID: 15125927
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of 4-quinolinone 2-carboxamides as calpain inhibitors.
    Nam DH; Lee KS; Kim SH; Kim SM; Jung SY; Chung SH; Kim HJ; Kim ND; Jin C; Lee YS
    Bioorg Med Chem Lett; 2008 Jan; 18(1):205-9. PubMed ID: 18024028
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Solid-phase combinatorial synthesis of peptide-biphenyl hybrids as calpain inhibitors.
    Montero A; Albericio F; Royo M; Herradón B
    Org Lett; 2004 Oct; 6(22):4089-92. PubMed ID: 15496106
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A straightforward synthesis of tetrameric estrone-based macrocycles.
    Ramírez-López P; de la Torre MC; Montenegro HE; Asenjo M; Sierra MA
    Org Lett; 2008 Aug; 10(16):3555-8. PubMed ID: 18646766
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Macrocyclic inhibitors of beta-secretase: functional activity in an animal model.
    Stachel SJ; Coburn CA; Sankaranarayanan S; Price EA; Wu G; Crouthamel M; Pietrak BL; Huang Q; Lineberger J; Espeseth AS; Jin L; Ellis J; Holloway MK; Munshi S; Allison T; Hazuda D; Simon AJ; Graham SL; Vacca JP
    J Med Chem; 2006 Oct; 49(21):6147-50. PubMed ID: 17034118
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oxidative α,ω-diyne coupling as an approach towards novel peptidic macrocycles.
    Verlinden S; Geudens N; Martins JC; Tourwé D; Ballet S; Verniest G
    Org Biomol Chem; 2015 Sep; 13(36):9398-404. PubMed ID: 26246017
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.