These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia. Feng Z; Yao Y; Zhou C; Chen F; Wu F; Wei L; Liu W; Dong S; Redell M; Mo Q; Song Y J Hematol Oncol; 2016 Mar; 9():24. PubMed ID: 26970896 [TBL] [Abstract][Full Text] [Related]
23. Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner. Jin L; Hanigan CL; Wu Y; Wang W; Park BH; Woster PM; Casero RA Biochem J; 2013 Jan; 449(2):459-68. PubMed ID: 23072722 [TBL] [Abstract][Full Text] [Related]
25. Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer. Tan AHY; Tu W; McCuaig R; Hardy K; Donovan T; Tsimbalyuk S; Forwood JK; Rao S Front Immunol; 2019; 10():1351. PubMed ID: 31249575 [TBL] [Abstract][Full Text] [Related]
26. Inhibition of LSD1 by Pargyline inhibited process of EMT and delayed progression of prostate cancer in vivo. Wang M; Liu X; Guo J; Weng X; Jiang G; Wang Z; He L Biochem Biophys Res Commun; 2015 Nov; 467(2):310-5. PubMed ID: 26435505 [TBL] [Abstract][Full Text] [Related]
27. Nucleosome Binding by the Lysine Specific Demethylase 1 (LSD1) Enzyme Enables Histone H3 Demethylation. Dhall A; Shelton PMM; Delachat AM; Leonen CJA; Fierz B; Chatterjee C Biochemistry; 2020 Jul; 59(27):2479-2483. PubMed ID: 32567837 [TBL] [Abstract][Full Text] [Related]
28. Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing Structures. Ota Y; Kakizawa T; Itoh Y; Suzuki T Molecules; 2018 May; 23(5):. PubMed ID: 29734782 [TBL] [Abstract][Full Text] [Related]
29. Structural basis of histone demethylation by LSD1 revealed by suicide inactivation. Yang M; Culhane JC; Szewczuk LM; Gocke CB; Brautigam CA; Tomchick DR; Machius M; Cole PA; Yu H Nat Struct Mol Biol; 2007 Jun; 14(6):535-9. PubMed ID: 17529991 [TBL] [Abstract][Full Text] [Related]
30. Epigenetic regulation of epithelial to mesenchymal transition by the Lysine-specific demethylase LSD1/KDM1A. Ambrosio S; Saccà CD; Majello B Biochim Biophys Acta Gene Regul Mech; 2017 Sep; 1860(9):905-910. PubMed ID: 28720390 [TBL] [Abstract][Full Text] [Related]
31. LSD1 knockdown reveals novel histone lysine methylation in human breast cancer MCF-7 cells. Jin Y; Huo B; Fu X; Cheng Z; Zhu J; Zhang Y; Hao T; Hu X Biomed Pharmacother; 2017 Aug; 92():896-904. PubMed ID: 28601046 [TBL] [Abstract][Full Text] [Related]
32. T-448, a specific inhibitor of LSD1 enzyme activity, improves learning function without causing thrombocytopenia in mice. Matsuda S; Baba R; Oki H; Morimoto S; Toyofuku M; Igaki S; Kamada Y; Iwasaki S; Matsumiya K; Hibino R; Kamada H; Hirakawa T; Iwatani M; Tsuchida K; Hara R; Ito M; Kimura H Neuropsychopharmacology; 2019 Jul; 44(8):1505-1512. PubMed ID: 30580376 [TBL] [Abstract][Full Text] [Related]
33. Irreversible LSD1 Inhibitors: Application of Tranylcypromine and Its Derivatives in Cancer Treatment. Zheng YC; Yu B; Jiang GZ; Feng XJ; He PX; Chu XY; Zhao W; Liu HM Curr Top Med Chem; 2016; 16(19):2179-88. PubMed ID: 26881714 [TBL] [Abstract][Full Text] [Related]
34. Identification of cell-active lysine specific demethylase 1-selective inhibitors. Ueda R; Suzuki T; Mino K; Tsumoto H; Nakagawa H; Hasegawa M; Sasaki R; Mizukami T; Miyata N J Am Chem Soc; 2009 Dec; 131(48):17536-7. PubMed ID: 19950987 [TBL] [Abstract][Full Text] [Related]
35. Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex. Kim SA; Chatterjee N; Jennings MJ; Bartholomew B; Tan S Nucleic Acids Res; 2015 May; 43(10):4868-80. PubMed ID: 25916846 [TBL] [Abstract][Full Text] [Related]
36. Raloxifene, identified as a novel LSD1 inhibitor, suppresses the migration of renal cell carcinoma. Ma Y; Zheng Y; Ji Y; Wang X; Ye B Future Med Chem; 2021 Mar; 13(6):533-542. PubMed ID: 33527838 [No Abstract] [Full Text] [Related]
37. Mining the Dynamical Properties of Substrate and FAD Binding Pockets of LSD1: Hints for New Inhibitor Design Direction. Yang K; Liu H J Chem Inf Model; 2024 Jun; 64(12):4773-4780. PubMed ID: 38837697 [TBL] [Abstract][Full Text] [Related]
38. Post-translational modifications of lysine-specific demethylase 1. Kim D; Nam HJ; Baek SH Biochim Biophys Acta Gene Regul Mech; 2023 Dec; 1866(4):194968. PubMed ID: 37572976 [TBL] [Abstract][Full Text] [Related]
39. Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1. Zhou C; Wu F; Lu L; Wei L; Pai E; Yao Y; Song Y PLoS One; 2017; 12(2):e0170301. PubMed ID: 28158205 [TBL] [Abstract][Full Text] [Related]
40. LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein SOX2. Zhang C; Hoang N; Leng F; Saxena L; Lee L; Alejo S; Qi D; Khal A; Sun H; Lu F; Zhang H J Biol Chem; 2018 Mar; 293(10):3663-3674. PubMed ID: 29358331 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]