These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 22342631)

  • 1. Novel hepatitis C virus replicon inhibitors: synthesis and structure-activity relationships of fused pyrimidine derivatives.
    Krueger AC; Madigan DL; Beno DW; Betebenner DA; Carrick R; Green BE; He W; Liu D; Maring CJ; McDaniel KF; Mo H; Molla A; Motter CE; Pilot-Matias TJ; Tufano MD; Kempf DJ
    Bioorg Med Chem Lett; 2012 Mar; 22(6):2212-5. PubMed ID: 22342631
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication.
    Clark JL; Mason JC; Hollecker L; Stuyver LJ; Tharnish PM; McBrayer TR; Otto MJ; Furman PA; Schinazi RF; Watanabe KA
    Bioorg Med Chem Lett; 2006 Mar; 16(6):1712-5. PubMed ID: 16368235
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of 9-(2-beta-C-methyl-beta-d-ribofuranosyl)-6-substituted purine derivatives as inhibitors of HCV RNA replication.
    Ding Y; Girardet JL; Hong Z; Lai VC; An H; Koh YH; Shaw SZ; Zhong W
    Bioorg Med Chem Lett; 2005 Feb; 15(3):709-13. PubMed ID: 15664842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well.
    Mondal R; Koev G; Pilot-Matias T; He Y; Ng T; Kati W; Molla A
    Antiviral Res; 2009 Apr; 82(1):82-8. PubMed ID: 19174175
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of new acridone derivatives, inhibitors of NS3 helicase, which efficiently and specifically inhibit subgenomic HCV replication.
    Stankiewicz-Drogoń A; Dörner B; Erker T; Boguszewska-Chachulska AM
    J Med Chem; 2010 Apr; 53(8):3117-26. PubMed ID: 20337460
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3-Amino-2(5H)furanones as inhibitors of subgenomic hepatitis C virus RNA replication.
    Iannazzo D; Piperno A; Romeo G; Romeo R; Chiacchio U; Rescifina A; Balestrieri E; Macchi B; Mastino A; Cortese R
    Bioorg Med Chem; 2008 Nov; 16(21):9610-5. PubMed ID: 18835180
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine.
    Smith DB; Kalayanov G; Sund C; Winqvist A; Pinho P; Maltseva T; Morisson V; Leveque V; Rajyaguru S; Le Pogam S; Najera I; Benkestock K; Zhou XX; Maag H; Cammack N; Martin JA; Swallow S; Johansson NG; Klumpp K; Smith M
    J Med Chem; 2009 Jan; 52(1):219-23. PubMed ID: 19055482
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preclinical Characterization and In Vivo Efficacy of GSK8853, a Small-Molecule Inhibitor of the Hepatitis C Virus NS4B Protein.
    Pouliot JJ; Thomson M; Xie M; Horton J; Johnson J; Krull D; Mathis A; Morikawa Y; Parks D; Peterson R; Shimada T; Thomas E; Vamathevan J; Van Horn S; Xiong Z; Hamatake R; Peat AJ
    Antimicrob Agents Chemother; 2015 Oct; 59(10):6539-50. PubMed ID: 26259798
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Establishment of a robust hepatitis C virus replicon cell line over-expressing P-glycoprotein that facilitates analysis of P-gp drug transporter effects on inhibitor antiviral activity.
    Hernandez D; Falk P; Yu F; Zhai G; Quan Y; Faria T; Cao K; Scola P; McPhee F
    Biochem Pharmacol; 2013 Jan; 85(1):21-8. PubMed ID: 23063413
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model.
    Umehara T; Sudoh M; Yasui F; Matsuda C; Hayashi Y; Chayama K; Kohara M
    Biochem Biophys Res Commun; 2006 Jul; 346(1):67-73. PubMed ID: 16750511
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.
    Clark JL; Hollecker L; Mason JC; Stuyver LJ; Tharnish PM; Lostia S; McBrayer TR; Schinazi RF; Watanabe KA; Otto MJ; Furman PA; Stec WJ; Patterson SE; Pankiewicz KW
    J Med Chem; 2005 Aug; 48(17):5504-8. PubMed ID: 16107149
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors.
    Kang IJ; Wang LW; Yeh TK; Lee CC; Lee YC; Hsu SJ; Wu YS; Wang JC; Chao YS; Yueh A; Chern JH
    Bioorg Med Chem; 2010 Sep; 18(17):6414-21. PubMed ID: 20675142
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exploration of the in vitro antiviral activity of a series of new pyrimidine analogues on the replication of HIV and HCV.
    Jafar NN; Al-Masoudi NA; Baqir SJ; Leyssen P; Pannecouque C
    Antivir Chem Chemother; 2012 Sep; 23(3):103-12. PubMed ID: 23010622
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Screening for hepatitis C virus antiviral activity with a cell-based secreted alkaline phosphatase reporter replicon system.
    Bourne N; Pyles RB; Yi M; Veselenak RL; Davis MM; Lemon SM
    Antiviral Res; 2005 Aug; 67(2):76-82. PubMed ID: 15927278
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and SAR of pyridothiazole substituted pyrimidine derived HCV replication inhibitors.
    Girijavallabhan VM; Alvarez C; Bennett F; Chen L; Gavalas S; Huang Y; Kim SH; Kosinski A; Pinto P; Rizvi R; Rossman R; Shankar B; Tong L; Velazquez F; Venkatraman S; Verma VA; Kozlowski J; Shih NY; Piwinski JJ; MacCoss M; Kwong CD; Bansal N; Clark JL; Fowler AT; Kezar HS; Valiyaveettil J; Reynolds RC; Maddry JA; Ananthan S; Secrist JA; Li C; Chase R; Curry S; Huang HC; Tong X; Njoroge FG; Arasappan A
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5652-7. PubMed ID: 22858143
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel substituted pyrimidines as HCV replication (replicase) inhibitors.
    Kwong CD; Clark JL; Fowler AT; Geng F; Kezar HS; Roychowdhury A; Reynolds RC; Maddry JA; Ananthan S; Secrist JA; Shih NY; Piwinski JJ; Li C; Feld B; Huang HC; Tong X; George Njoroge F; Arasappan A
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1160-4. PubMed ID: 22178556
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 4'-Substituted pyrimidine nucleosides lacking 5'-hydroxyl function as potential anti-HCV agents.
    Shakya N; Vedi S; Liang C; Yang F; Agrawal B; Kumar R
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1407-9. PubMed ID: 24485784
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and antiviral evaluation of 2'-C-methyl analogues of 5-alkynyl- and 6-alkylfurano- and pyrrolo[2,3-d]pyrimidine ribonucleosides.
    Januszczyk P; Fogt J; Boryski J; Izawa K; Onishi T; Neyts J; De Clercq E
    Nucleosides Nucleotides Nucleic Acids; 2009 May; 28(5):713-23. PubMed ID: 20183611
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of α-aryl-α-tetralone derivatives as hepatitis C virus inhibitors.
    Manvar D; Fernandes Tde A; Domingos JL; Baljinnyam E; Basu A; Junior EF; Costa PR; Kaushik-Basu N
    Eur J Med Chem; 2015 Mar; 93():51-4. PubMed ID: 25644675
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors.
    Kang IJ; Wang LW; Hsu SJ; Lee CC; Lee YC; Wu YS; Yueh A; Wang JC; Hsu TA; Chao YS; Chern JH
    Bioorg Med Chem Lett; 2009 Nov; 19(21):6063-8. PubMed ID: 19796940
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.