174 related articles for article (PubMed ID: 22342989)
1. Separate regions of glucocorticoid receptor, coactivator TIF2, and comodulator STAMP modify different parameters of glucocorticoid-mediated gene induction.
Awasthi S; Simons SS
Mol Cell Endocrinol; 2012 May; 355(1):121-34. PubMed ID: 22342989
[TBL] [Abstract][Full Text] [Related]
2. Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors.
Wang Q; Blackford JA; Song LN; Huang Y; Cho S; Simons SS
Mol Endocrinol; 2004 Jun; 18(6):1376-95. PubMed ID: 15016838
[TBL] [Abstract][Full Text] [Related]
3. Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor-regulated gene expression.
Szapary D; Huang Y; Simons SS
Mol Endocrinol; 1999 Dec; 13(12):2108-21. PubMed ID: 10598585
[TBL] [Abstract][Full Text] [Related]
4. Modulation of transcription parameters in glucocorticoid receptor-mediated repression.
Sun Y; Tao YG; Kagan BL; He Y; Simons SS
Mol Cell Endocrinol; 2008 Nov; 295(1-2):59-69. PubMed ID: 18583028
[TBL] [Abstract][Full Text] [Related]
5. Modulation of induction properties of glucocorticoid receptor-agonist and -antagonist complexes by coactivators involves binding to receptors but is independent of ability of coactivators to augment transactivation.
He Y; Szapary D; Simons SS
J Biol Chem; 2002 Dec; 277(51):49256-66. PubMed ID: 12376547
[TBL] [Abstract][Full Text] [Related]
6. Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors.
Lee GS; Simons SS
Biochemistry; 2011 Jan; 50(3):356-66. PubMed ID: 21142156
[TBL] [Abstract][Full Text] [Related]
7. Binding of the N-terminal region of coactivator TIF2 to the intrinsically disordered AF1 domain of the glucocorticoid receptor is accompanied by conformational reorganizations.
Khan SH; Awasthi S; Guo C; Goswami D; Ling J; Griffin PR; Simons SS; Kumar R
J Biol Chem; 2012 Dec; 287(53):44546-60. PubMed ID: 23132854
[TBL] [Abstract][Full Text] [Related]
8. Modulation of glucocorticoid receptor induction properties by cofactors in peripheral blood mononuclear cells.
Luo M; Simons SS
Hum Immunol; 2009 Oct; 70(10):785-9. PubMed ID: 19665040
[TBL] [Abstract][Full Text] [Related]
9. STAMP, a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression.
He Y; Simons SS
Mol Cell Biol; 2007 Feb; 27(4):1467-85. PubMed ID: 17116691
[TBL] [Abstract][Full Text] [Related]
10. Glucocorticoid receptor ligand binding domain is sufficient for the modulation of glucocorticoid induction properties by homologous receptors, coactivator transcription intermediary factor 2, and Ubc9.
Cho S; Kagan BL; Blackford JA; Szapary D; Simons SS
Mol Endocrinol; 2005 Feb; 19(2):290-311. PubMed ID: 15539428
[TBL] [Abstract][Full Text] [Related]
11. Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression.
Tao YG; Xu Y; Xu HE; Simons SS
Biochemistry; 2008 Jul; 47(29):7648-62. PubMed ID: 18578507
[TBL] [Abstract][Full Text] [Related]
12. Glucocorticoid receptor cofactors as therapeutic targets.
Simons SS
Curr Opin Pharmacol; 2010 Dec; 10(6):613-9. PubMed ID: 20801081
[TBL] [Abstract][Full Text] [Related]
13. Evidence for a common step in three different processes for modulating the kinetic properties of glucocorticoid receptor-induced gene transcription.
Chen S; Sarlis NJ; Simons SS
J Biol Chem; 2000 Sep; 275(39):30106-17. PubMed ID: 10899170
[TBL] [Abstract][Full Text] [Related]
14. PA1 protein, a new competitive decelerator acting at more than one step to impede glucocorticoid receptor-mediated transactivation.
Zhang Z; Sun Y; Cho YW; Chow CC; Simons SS
J Biol Chem; 2013 Jan; 288(1):42-58. PubMed ID: 23161582
[TBL] [Abstract][Full Text] [Related]
15. New antiprogestins with partial agonist activity: potential selective progesterone receptor modulators (SPRMs) and probes for receptor- and coregulator-induced changes in progesterone receptor induction properties.
Giannoukos G; Szapary D; Smith CL; Meeker JE; Simons SS
Mol Endocrinol; 2001 Feb; 15(2):255-70. PubMed ID: 11158332
[TBL] [Abstract][Full Text] [Related]
16. Quantity of partial agonist activity for antiglucocorticoids complexed with mutant glucocorticoid receptors is constant in two different transactivation assays but not predictable from steroid structure.
Sarlis NJ; Bayly SF; Szapary D; Simons SS
J Steroid Biochem Mol Biol; 1999 Feb; 68(3-4):89-102. PubMed ID: 10369406
[TBL] [Abstract][Full Text] [Related]
17. Amino-terminal domain of TIF2 is involved in competing for corepressor binding to glucocorticoid and progesterone receptors.
Wang D; Wang Q; Awasthi S; Simons SS
Biochemistry; 2007 Jul; 46(27):8036-49. PubMed ID: 17571860
[TBL] [Abstract][Full Text] [Related]
18. Role of activation function domain-1, DNA binding, and coactivator GRIP1 in the expression of partial agonist activity of glucocorticoid receptor-antagonist complexes.
Cho S; Blackford JA; Simons SS
Biochemistry; 2005 Mar; 44(9):3547-61. PubMed ID: 15736964
[TBL] [Abstract][Full Text] [Related]
19. Receptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoids.
Subramaniam N; Treuter E; Okret S
J Biol Chem; 1999 Jun; 274(25):18121-7. PubMed ID: 10364267
[TBL] [Abstract][Full Text] [Related]
20. Deducing the temporal order of cofactor function in ligand-regulated gene transcription: theory and experimental verification.
Dougherty EJ; Guo C; Simons SS; Chow CC
PLoS One; 2012; 7(1):e30225. PubMed ID: 22272313
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]