167 related articles for article (PubMed ID: 22343093)
1. Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease.
Ezgimen M; Lai H; Mueller NH; Lee K; Cuny G; Ostrov DA; Padmanabhan R
Antiviral Res; 2012 Apr; 94(1):18-24. PubMed ID: 22343093
[TBL] [Abstract][Full Text] [Related]
2. Characterization of 8-hydroxyquinoline derivatives containing aminobenzothiazole as inhibitors of dengue virus type 2 protease in vitro.
Lai H; Sridhar Prasad G; Padmanabhan R
Antiviral Res; 2013 Jan; 97(1):74-80. PubMed ID: 23127365
[TBL] [Abstract][Full Text] [Related]
3. Identification and biochemical characterization of small-molecule inhibitors of west nile virus serine protease by a high-throughput screen.
Mueller NH; Pattabiraman N; Ansarah-Sobrinho C; Viswanathan P; Pierson TC; Padmanabhan R
Antimicrob Agents Chemother; 2008 Sep; 52(9):3385-93. PubMed ID: 18606844
[TBL] [Abstract][Full Text] [Related]
4. HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus.
Johnston PA; Phillips J; Shun TY; Shinde S; Lazo JS; Huryn DM; Myers MC; Ratnikov BI; Smith JW; Su Y; Dahl R; Cosford ND; Shiryaev SA; Strongin AY
Assay Drug Dev Technol; 2007 Dec; 5(6):737-50. PubMed ID: 18181690
[TBL] [Abstract][Full Text] [Related]
5. Characterization of the West Nile virus protease substrate specificity and inhibitors.
Mueller NH; Yon C; Ganesh VK; Padmanabhan R
Int J Biochem Cell Biol; 2007; 39(3):606-14. PubMed ID: 17188926
[TBL] [Abstract][Full Text] [Related]
6. Tripeptide inhibitors of dengue and West Nile virus NS2B-NS3 protease.
Schüller A; Yin Z; Brian Chia CS; Doan DN; Kim HK; Shang L; Loh TP; Hill J; Vasudevan SG
Antiviral Res; 2011 Oct; 92(1):96-101. PubMed ID: 21763725
[TBL] [Abstract][Full Text] [Related]
7. Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking.
Ekonomiuk D; Su XC; Ozawa K; Bodenreider C; Lim SP; Yin Z; Keller TH; Beer D; Patel V; Otting G; Caflisch A; Huang D
PLoS Negl Trop Dis; 2009; 3(1):e356. PubMed ID: 19159012
[TBL] [Abstract][Full Text] [Related]
8. A FRET-based assay for the discovery of West Nile Virus NS2B-NS3 protease inhibitors.
Adamek RN; Maniquis RV; Khakoo S; Bridges MD; Salzameda NT
Bioorg Med Chem Lett; 2013 Sep; 23(17):4848-50. PubMed ID: 23886689
[TBL] [Abstract][Full Text] [Related]
9. Isolation and characterization of selective and potent human Fab inhibitors directed to the active-site region of the two-component NS2B-NS3 proteinase of West Nile virus.
Shiryaev SA; Radichev IA; Ratnikov BI; Aleshin AE; Gawlik K; Stec B; Frisch C; Knappik A; Strongin AY
Biochem J; 2010 Apr; 427(3):369-76. PubMed ID: 20156198
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and in vitro evaluation of West Nile virus protease inhibitors based on the 1,3,4,5-tetrasubstituted 1H-pyrrol-2(5H)-one scaffold.
Gao Y; Samanta S; Cui T; Lam Y
ChemMedChem; 2013 Sep; 8(9):1554-60. PubMed ID: 23868614
[TBL] [Abstract][Full Text] [Related]
11. Structure-activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase.
Sidique S; Shiryaev SA; Ratnikov BI; Herath A; Su Y; Strongin AY; Cosford ND
Bioorg Med Chem Lett; 2009 Oct; 19(19):5773-7. PubMed ID: 19703770
[TBL] [Abstract][Full Text] [Related]
12. Inhibitors of Dengue virus and West Nile virus proteases based on the aminobenzamide scaffold.
Aravapalli S; Lai H; Teramoto T; Alliston KR; Lushington GH; Ferguson EL; Padmanabhan R; Groutas WC
Bioorg Med Chem; 2012 Jul; 20(13):4140-8. PubMed ID: 22632792
[TBL] [Abstract][Full Text] [Related]
13. Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication.
Kouretova J; Hammamy MZ; Epp A; Hardes K; Kallis S; Zhang L; Hilgenfeld R; Bartenschlager R; Steinmetzer T
J Enzyme Inhib Med Chem; 2017 Dec; 32(1):712-721. PubMed ID: 28385094
[TBL] [Abstract][Full Text] [Related]
14. Identification of a novel inhibitor of dengue virus protease through use of a virtual screening drug discovery Web portal.
Viswanathan U; Tomlinson SM; Fonner JM; Mock SA; Watowich SJ
J Chem Inf Model; 2014 Oct; 54(10):2816-25. PubMed ID: 25263519
[TBL] [Abstract][Full Text] [Related]
15. Dengue protease activity: the structural integrity and interaction of NS2B with NS3 protease and its potential as a drug target.
Phong WY; Moreland NJ; Lim SP; Wen D; Paradkar PN; Vasudevan SG
Biosci Rep; 2011 Oct; 31(5):399-409. PubMed ID: 21329491
[TBL] [Abstract][Full Text] [Related]
16. Arylcyanoacrylamides as inhibitors of the Dengue and West Nile virus proteases.
Nitsche C; Steuer C; Klein CD
Bioorg Med Chem; 2011 Dec; 19(24):7318-37. PubMed ID: 22094280
[TBL] [Abstract][Full Text] [Related]
17. Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase.
Radichev I; Shiryaev SA; Aleshin AE; Ratnikov BI; Smith JW; Liddington RC; Strongin AY
J Gen Virol; 2008 Mar; 89(Pt 3):636-641. PubMed ID: 18272753
[TBL] [Abstract][Full Text] [Related]
18. Profiling of flaviviral NS2B-NS3 protease specificity provides a structural basis for the development of selective chemical tools that differentiate Dengue from Zika and West Nile viruses.
Rut W; Groborz K; Zhang L; Modrzycka S; Poreba M; Hilgenfeld R; Drag M
Antiviral Res; 2020 Mar; 175():104731. PubMed ID: 32014497
[TBL] [Abstract][Full Text] [Related]
19. West Nile Virus NS2B/NS3 protease as an antiviral target.
Chappell KJ; Stoermer MJ; Fairlie DP; Young PR
Curr Med Chem; 2008; 15(27):2771-84. PubMed ID: 18991636
[TBL] [Abstract][Full Text] [Related]
20. STD-NMR experiments identify a structural motif with novel second-site activity against West Nile virus NS2B-NS3 protease.
Schöne T; Grimm LL; Sakai N; Zhang L; Hilgenfeld R; Peters T
Antiviral Res; 2017 Oct; 146():174-183. PubMed ID: 28927677
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
