244 related articles for article (PubMed ID: 22347438)
1. Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1α.
Schilling D; Bayer C; Li W; Molls M; Vaupel P; Multhoff G
PLoS One; 2012; 7(2):e31110. PubMed ID: 22347438
[TBL] [Abstract][Full Text] [Related]
2. Targeting heat shock protein 90 overrides the resistance of lung cancer cells by blocking radiation-induced stabilization of hypoxia-inducible factor-1alpha.
Kim WY; Oh SH; Woo JK; Hong WK; Lee HY
Cancer Res; 2009 Feb; 69(4):1624-32. PubMed ID: 19176399
[TBL] [Abstract][Full Text] [Related]
3. Hsp90 inhibitor NVP-AUY922 enhances radiation sensitivity of tumor cell lines under hypoxia.
Djuzenova CS; Blassl C; Roloff K; Kuger S; Katzer A; Niewidok N; Günther N; Polat B; Sukhorukov VL; Flentje M
Cancer Biol Ther; 2012 Apr; 13(6):425-34. PubMed ID: 22286776
[TBL] [Abstract][Full Text] [Related]
4. Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922.
Kühnel A; Schilling D; Combs SE; Haller B; Schwab M; Multhoff G
Cells; 2019 Sep; 8(10):. PubMed ID: 31569342
[TBL] [Abstract][Full Text] [Related]
5. Basal HIF-1α expression levels are not predictive for radiosensitivity of human cancer cell lines.
Schilling D; Bayer C; Emmerich K; Molls M; Vaupel P; Huber RM; Multhoff G
Strahlenther Onkol; 2012 Apr; 188(4):353-8. PubMed ID: 22318330
[TBL] [Abstract][Full Text] [Related]
6. Hypoxia inducible factor-1α/B-cell lymphoma 2 signaling impacts radiosensitivity of H1299 non-small cell lung cancer cells in a normoxic environment.
Wang G; Xiao L; Wang F; Yang J; Yang L; Zhao Y; Jin W
Radiat Environ Biophys; 2019 Aug; 58(3):439-448. PubMed ID: 31203382
[TBL] [Abstract][Full Text] [Related]
7. Role of membrane Hsp70 in radiation sensitivity of tumor cells.
Murakami N; Kühnel A; Schmid TE; Ilicic K; Stangl S; Braun IS; Gehrmann M; Molls M; Itami J; Multhoff G
Radiat Oncol; 2015 Jul; 10():149. PubMed ID: 26197988
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of HSP90 overcomes resistance to chemotherapy and radiotherapy in pancreatic cancer.
Nagaraju GP; Zakka KM; Landry JC; Shaib WL; Lesinski GB; El-Rayes BF
Int J Cancer; 2019 Sep; 145(6):1529-1537. PubMed ID: 30801702
[TBL] [Abstract][Full Text] [Related]
9. Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotopic tumor growth.
Lang SA; Moser C; Gaumann A; Klein D; Glockzin G; Popp FC; Dahlke MH; Piso P; Schlitt HJ; Geissler EK; Stoeltzing O
Clin Cancer Res; 2007 Nov; 13(21):6459-68. PubMed ID: 17975158
[TBL] [Abstract][Full Text] [Related]
10. Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule.
Djuzenova CS; Fiedler V; Katzer A; Michel K; Deckert S; Zimmermann H; Sukhorukov VL; Flentje M
Oncotarget; 2016 Jun; 7(25):38191-38209. PubMed ID: 27224913
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.
Lang SA; Klein D; Moser C; Gaumann A; Glockzin G; Dahlke MH; Dietmaier W; Bolder U; Schlitt HJ; Geissler EK; Stoeltzing O
Mol Cancer Ther; 2007 Mar; 6(3):1123-32. PubMed ID: 17363505
[TBL] [Abstract][Full Text] [Related]
12. Ηypoxia-inducible factor-1α, von Hippel-Lindau protein, and heat shock protein expression in ophthalmic pterygium and normal conjunctiva.
Pagoulatos D; Pharmakakis N; Lakoumentas J; Assimakopoulou M
Mol Vis; 2014; 20():441-57. PubMed ID: 24715760
[TBL] [Abstract][Full Text] [Related]
13. Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.
Katschinski DM; Le L; Schindler SG; Thomas T; Voss AK; Wenger RH
Cell Physiol Biochem; 2004; 14(4-6):351-60. PubMed ID: 15319539
[TBL] [Abstract][Full Text] [Related]
14. Induction of the hypoxia-inducible factor system by low levels of heat shock protein 90 inhibitors.
Ibrahim NO; Hahn T; Franke C; Stiehl DP; Wirthner R; Wenger RH; Katschinski DM
Cancer Res; 2005 Dec; 65(23):11094-100. PubMed ID: 16322259
[TBL] [Abstract][Full Text] [Related]
15. NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis.
Eccles SA; Massey A; Raynaud FI; Sharp SY; Box G; Valenti M; Patterson L; de Haven Brandon A; Gowan S; Boxall F; Aherne W; Rowlands M; Hayes A; Martins V; Urban F; Boxall K; Prodromou C; Pearl L; James K; Matthews TP; Cheung KM; Kalusa A; Jones K; McDonald E; Barril X; Brough PA; Cansfield JE; Dymock B; Drysdale MJ; Finch H; Howes R; Hubbard RE; Surgenor A; Webb P; Wood M; Wright L; Workman P
Cancer Res; 2008 Apr; 68(8):2850-60. PubMed ID: 18413753
[TBL] [Abstract][Full Text] [Related]
16. Regulation of hypoxia-induced mRNA expressions of HIF-1alpha and osteopontin and in vitro radiosensitization by tirapazamine in human nasopharyngeal carcinoma HNE-1 and CNE-1 cells.
Xu P; Huang JM; Ren Y; Zha X; Deng BF; Wu JH; Lang JY
Chin J Cancer; 2010 Feb; 29(2):126-30. PubMed ID: 20109337
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of hypoxia-inducible factor-1 alpha radiosensitized MG-63 human osteosarcoma cells in vitro.
Jin Z; Aixi Y; Baiwen Q; Zonghuan L; Xiang H
Tumori; 2015; 101(5):578-84. PubMed ID: 26350185
[TBL] [Abstract][Full Text] [Related]
18. Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy.
Barliya T; Mandel M; Livnat T; Weinberger D; Lavie G
PLoS One; 2011; 6(9):e22849. PubMed ID: 21949677
[TBL] [Abstract][Full Text] [Related]
19. The Hsp70 inhibiting peptide aptamer A17 potentiates radiosensitization of tumor cells by Hsp90 inhibition.
Schilling D; Garrido C; Combs SE; Multhoff G
Cancer Lett; 2017 Apr; 390():146-152. PubMed ID: 28108313
[TBL] [Abstract][Full Text] [Related]
20. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
Zhou J; Schmid T; Frank R; Brüne B
J Biol Chem; 2004 Apr; 279(14):13506-13. PubMed ID: 14726529
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
